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Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Tercica files for patent infringement

Tercica announced today the filing of a suit for patent infringement in the High Court of Justice (Chancery Division Patents Court) in the United Kingdom against Insmed Incorporated of Glen Allen, Virginia and Avecia Limited of the United Kingdom.

20 Dec 2004

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Cardiovascular disease risk is extremely high in adults with diabetes. Yet women as well as people under 50 who have diabetes do not use aspirin, despite the fact that aspirin has been found an effective and inexpensive means to reduce risk of first and subsequent heart attack.

20 Dec 2004

Blocking gene's activity may control deadly skin cancer without harming normal cells

Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without.

20 Dec 2004

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

Blocking a key molecule protects breast implants, permanent catheters, pacemakers, artificial joints, glucose sensors for diabetics, and other biomaterials from rejection and damage by the body, according to a study published this month in The American Journal of Pathology.

20 Dec 2004

Cherries could help lower blood sugar levels in people with diabetes

Perhaps George Washington wouldn't have chopped down his father's cherry tree if he knew what chemists now know. They have identified a group of naturally occurring chemicals abundant in cherries that could help lower blood sugar levels in people with diabetes.

20 Dec 2004

DLX5 gene may play a role in the pathology of Rett Syndrome

A research team led by Terumi Kohwi-Shigematsu of the Life Sciences Division of Lawrence Berkeley National Laboratory has identified a gene, DLX5, that may play a role in the pathology of Rett Syndrome, a devastating neurological disorder diagnosed almost exclusively in girls.

20 Dec 2004

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Agents designed to attack blood vessels that feed a growing tumor are effective against tumor growth in laboratory experiments. However, results of early clinical trials with these inhibitors have not yet exhibited the same success observed in animal models.

20 Dec 2004

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Scientists funded by the National Institute of Dental and Craniofacial Research reported today taking a major step forward in using saliva to detect oral cancer.

20 Dec 2004

Emergency room patients with substance abuse treatment need incur higher health care costs

Emergency department patients with unmet substance abuse treatment need generate much higher hospital and emergency department charges than patients without such need, according to a new study to be published today as an advance online publication of Annals of Emergency Medicine.

20 Dec 2004

Health impact of resolving racial disparities

Lives saved by reducing the mortality rate of African-Americans to the rate of whites are five times those that could be saved by improvements in medical technology. So said the authors of "The Health Impact of Resolving Racial Disparities: An Analysis of US Mortality Data," published in the December edition of the American Journal of Public Health.

20 Dec 2004

European market for bone morphogenic proteins in spine fusion

High growth is forecast for novel technologies used either as adjuncts or as alternatives to current surgical procedures for the fusion of spinal vertebrae. Bone morphogenic proteins (BMP) - a new and innovative class of natural growth factors - represent amongst the most exciting of these niches.

20 Dec 2004

Size of myocardial infarct measured using MRI

In animal studies, researchers at Johns Hopkins have effectively used magnetic resonance imaging (MRI) to measure with 94 percent accuracy the size and amount of heart muscle damaged by a heart attack, known in medical terms as a myocardial infarct, or m.i., for short.

20 Dec 2004

Patients with abdominal trauma at risk for intra-abdominal infections following surgery

Patients who undergo surgery for abdominal trauma caused by firearm wounds or by blunt trauma are at risk for developing intra-abdominal infections, and several factors increase that risk, according to a study in the December issue of The Archives of Surgery.

20 Dec 2004

At-home hand dermatitis treatment with oral medication and use of a portable tanning effective treatment for hand eczema

An at-home hand dermatitis treatment with oral medication and use of a portable tanning unit appears to be as effective as a hospital-based treatment in reducing the symptoms of hand dermatitis, according to an article in the December issue of The Archives of Dermatology.

20 Dec 2004

Oral medication alitretinoin effective in treating moderate or severe hand dermatitis

Use of the oral medication alitretinoin was effective in treating moderate or severe hand dermatitis in nearly half of patients previously unresponsive to standard treatment, according to an article in the December issue of The Archives of Dermatology.

20 Dec 2004

Genetic markers implicated in fatal side effects of schizophrenia drug

Genaissance Pharmaceuticals today announced results from its CARING (Clozapine and Agranulocytosis Relationships Investigated by Genetics) study, reporting the discovery of genetic markers that the Company believes predict who is at risk of developing clozapine-induced agranulocytosis

20 Dec 2004

Computer gamers’ state of mind subject of research

Central Queensland University researcher Dr Steve Pace has been awarded a $10 000 grant to study the experiences of computer game players. The study will focus on two specific phenomena called 'flow' and 'telepresence'.

20 Dec 2004

Nearly 6 million Americans turned to complementary and alternative medicine because of costs

Nearly 6 million American adults turned to complementary and alternative medicine (CAM) in the past year to treat such conditions as depression and chronic pain because conventional medical treatment was too expensive, according to a national study released today by the Center for Studying Health System Change (HSC).

20 Dec 2004

Stem cells use inflammatory signals to find injured tissue

A joint effort led by stem cell biologist Evan Y. Snyder, M.D., Ph.D., of The Burnham Institute, and Samia J. Khoury, M.D., of Harvard Medical School and Brigham and Women’s Hospital, report data suggesting that stem cells use inflammatory signals to “know” where they must home.

20 Dec 2004

Medical News

Study on first new potential drug for tuberculosis in 40 years

Tercica files for patent infringement

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Blocking gene's activity may control deadly skin cancer without harming normal cells

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

Cherries could help lower blood sugar levels in people with diabetes

DLX5 gene may play a role in the pathology of Rett Syndrome

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Emergency room patients with substance abuse treatment need incur higher health care costs

Health impact of resolving racial disparities

European market for bone morphogenic proteins in spine fusion

Size of myocardial infarct measured using MRI

Patients with abdominal trauma at risk for intra-abdominal infections following surgery

At-home hand dermatitis treatment with oral medication and use of a portable tanning effective treatment for hand eczema

Oral medication alitretinoin effective in treating moderate or severe hand dermatitis

Genetic markers implicated in fatal side effects of schizophrenia drug

Computer gamers’ state of mind subject of research

Nearly 6 million Americans turned to complementary and alternative medicine because of costs

Stem cells use inflammatory signals to find injured tissue

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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