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Defibrillators plentiful in schools but not senior centers

A greater percentage of high schools had automated external defibrillators (AEDs) - devices that can be used to treat cardiac arrest victims - than senior centers, despite the fact that cardiac arrests appear more common in senior centers, according to a study by University of Iowa researchers.

20 Oct 2005

Researchers discover the presence of functional ion channels in human embryonic stem cells

These ion channels act like electrical wires and permit ESCs, versatile cells that possess the unique ability to become all cell types of the body, to conduct and pass along electric currents.

20 Oct 2005

Menin is a key player in the development of some forms of acute leukemia

Tumor-suppressor proteins work to inhibit tumor growth in our bodies and when they win, they spare us a battle with cancer. But one such protein, menin, appears to have a split personality.

20 Oct 2005

Researchers learn to rapidly rebuild immunity in immune-suppressed cancer patients

Patients with multiple myeloma suffer from a malignant proliferation of plasma cells in their bone marrow. The standard treatment for this form of cancer is high-dose chemotherapy and transplantation of one's own blood-producing adult stem cells; however, this aggressive treatment wipes out the mature immune-system cells of patients – leaving them vulnerable to infection.

20 Oct 2005

Hepatitis C linked to illegal blood donation in China

Research in a rural province of central China has documented that illegal blood donation practices led to high hepatitis C virus (HCV) infection rates in blood and plasma donors during the 1980s and early 1990s, and that failure to screen for HCV in transfusion recipients increased their risk of infection as well

20 Oct 2005

Discovery of a new kind of messenger RNA molecule

Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection.

20 Oct 2005

Spliceosome crucial for processing non-coding RNA

The discovery in 1977 that the coding regions of a gene could appear in separate segments along the DNA won the 1993 Nobel Prize in Physiology or Medicine for Richard J. Roberts and Phillip A. Sharp. The active segments of a gene were termed exons, separated from each other within the gene by inactive introns.

20 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

Alzheimer disease and the blood brain barrier

Increased production of the amyloid-beta (Abeta) peptide can lead to Abeta aggregation and buildup in the brain and rare familial forms of early onset Alzheimer disease (AD).

20 Oct 2005

Link between emotional impairment and poor cognition in children with bipolar disorder

Using functional magnetic resonance imaging, Pavuluri and her colleagues examined the brain activity of teens while they were performing certain mental tasks. The researchers scanned the brains of 10 unmedicated bipolar patients with normal mood and compared them with 10 healthy subjects of the same age and gender.

20 Oct 2005

Diet rich in fruits and vegetables could be a good defense against prostate cancer

Previous studies have suggested that increased intake of flavonoids which are common in fruits and vegetables may be associated with a reduced risk of prostate cancer, according to Sanjay Gupta, Ph.D., an assistant professor in the Case School of Medicine Department of Urology.

20 Oct 2005

Identification of a factor in human milk that can block HIV-1 transmission

Mother to child transmission of HIV accounts for a large proportion of HIV infections in children, with many infected as a result of breastfeeding, which requires transfer of the virus across mucosal barriers. DC-SIGN, a DC lectin receptor, interacts with HIV and is found at high expression levels in tonsillar tissue.

20 Oct 2005

Retiring early is not linked to longer life

There is a widespread perception that early retirement is associated with longer life expectancy and later retirement is associated with early death. But no consensus has been reached on the effect of early retirement on survival.

20 Oct 2005

NHS needs an independent regulator

The NHS should have an independent regulator like other public utilities in the UK, argues a senior doctor in this week’s British Medical Journal.

20 Oct 2005

U.S. health inequalities cause 84,000 extra deaths every year

Research estimates that health inequalities between white and black Americans cause 84,000 extra deaths every year – equating to a virtual hurricane Katrina every week, says an editorial in this week’s British Medical Journal.

20 Oct 2005

Separate guidelines needed for the treatment of organophosphorus insecticide self-poisoning

Organophosphorus insecticide poisoning is a major global health problem, with hundreds of thousands of deaths each year. Most of these are in developing countries but this type of poisoning is also an important type of self-poisoning in the developed countries.

20 Oct 2005

Interventions to improve child survival are not reaching the poorest children

In most low-income countries, coverage rates for child-survival interventions are low, and millions of children die every year from diseases for which there are effective interventions.

20 Oct 2005

26% of HIV-infected individuals reported that they felt discriminated against by physicians

Research published in the Journal of General Internal Medicine reveals that 26% of HIV-infected individuals reported that they felt discriminated against by physicians and other health care providers. Despite demographic variations, all subgroups reported discrimination of some type.

20 Oct 2005

US Congress has wasted an opportunity to tackle the rising numbers of chronically hungry people in the world

On World Food Day, Oct 16, the World Food Programme (WFP) delivered some disquieting news: the number of chronically hungry people is rising again after decades of decline. Almost 6·5 million people have died so far this year from hunger and related diseases, which claim more lives than AIDS, malaria, and tuberculosis combined.

20 Oct 2005

Avian flu and planning for pandemic

Influenza season is almost upon us. While it is impossible to tell whether we are going to experience a usual flu season -- with one in every five people falling ill -- or whether we are facing a more serious problem such as a dangerous new strain capable of causing a global pandemic, information is important.

20 Oct 2005