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Cancer drug paclitaxel may reduce the adverse effects of Alzheimer's disease

In a preclinical efficacy trial, the cancer drug paclitaxel (Paxceed)–which exerts its effects by binding to and stabilizing microtubules inside cells–reduced the adverse effects of Alzheimer's disease (AD)-like pathology in a mouse model.

20 Dec 2004

FDA issues advice on Naproxen

The FDA has released the following statement on NIH halting a clinical trial involving non-steroidal anti-inflammatory drugs in patients at risk of developing Alzheimer's Disease:

20 Dec 2004

5000 year old system of medicine provides pain relief for people with osteoarthritis of the knee

A 5000 year old system of medicine, acupuncture provides pain relief and improves function for people with osteoarthritis of the knee and serves as an effective complement to standard care.

20 Dec 2004

PAHO - Cervical cancer kills almost a quarter-million women worldwide each year

The Pan American Health Organization (A regional office of the World Health Organization), as a member of the Alliance for Cervical Cancer Prevention (ACCP), has issued a new publication and reported that cervical cancer—while largely preventable—kills almost a quarter-million women worldwide each year.

20 Dec 2004

Confusion over Lasik eye surgery terminology

The Eye Surgery Education Council of the American Society of Cataract and Refractive Surgery Foundation today issued a clarification on the use of the terms "wavefront-guided," and "wavefront-optimized" in connection with laser-based procedures (LASIK, PRK, etc.) and implantable lenses used for vision correction purposes.

20 Dec 2004

Genzyme files for European approval of Myozyme for treatment of Pompe disease

Genzyme Corp. announced today that the European Medicines Agency (EMEA) has accepted its marketing authorization application for Myozyme(R) (alglucosidase alfa), an investigational enzyme replacement therapy for Pompe disease.

20 Dec 2004

Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Tercica files for patent infringement

Tercica announced today the filing of a suit for patent infringement in the High Court of Justice (Chancery Division Patents Court) in the United Kingdom against Insmed Incorporated of Glen Allen, Virginia and Avecia Limited of the United Kingdom.

20 Dec 2004

Aspirin overlooked as an effective and inexpensive means to reduce cardiovascular disease risk in diabetic women and young adults

Cardiovascular disease risk is extremely high in adults with diabetes. Yet women as well as people under 50 who have diabetes do not use aspirin, despite the fact that aspirin has been found an effective and inexpensive means to reduce risk of first and subsequent heart attack.

20 Dec 2004

Blocking gene's activity may control deadly skin cancer without harming normal cells

Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without.

20 Dec 2004

Blocking a key molecule protects breast implants, permanent catheters, pacemakers and artificial joints from rejection and damage by the body

Blocking a key molecule protects breast implants, permanent catheters, pacemakers, artificial joints, glucose sensors for diabetics, and other biomaterials from rejection and damage by the body, according to a study published this month in The American Journal of Pathology.

20 Dec 2004

Cherries could help lower blood sugar levels in people with diabetes

Perhaps George Washington wouldn't have chopped down his father's cherry tree if he knew what chemists now know. They have identified a group of naturally occurring chemicals abundant in cherries that could help lower blood sugar levels in people with diabetes.

20 Dec 2004

DLX5 gene may play a role in the pathology of Rett Syndrome

A research team led by Terumi Kohwi-Shigematsu of the Life Sciences Division of Lawrence Berkeley National Laboratory has identified a gene, DLX5, that may play a role in the pathology of Rett Syndrome, a devastating neurological disorder diagnosed almost exclusively in girls.

20 Dec 2004

Timing of radiation and antiangiogenic therapy impacts treatment effectiveness

Agents designed to attack blood vessels that feed a growing tumor are effective against tumor growth in laboratory experiments. However, results of early clinical trials with these inhibitors have not yet exhibited the same success observed in animal models.

20 Dec 2004

Messenger RNA not only are measurable in saliva but can indicate a developing tumor

Scientists funded by the National Institute of Dental and Craniofacial Research reported today taking a major step forward in using saliva to detect oral cancer.

20 Dec 2004

Emergency room patients with substance abuse treatment need incur higher health care costs

Emergency department patients with unmet substance abuse treatment need generate much higher hospital and emergency department charges than patients without such need, according to a new study to be published today as an advance online publication of Annals of Emergency Medicine.

20 Dec 2004

Health impact of resolving racial disparities

Lives saved by reducing the mortality rate of African-Americans to the rate of whites are five times those that could be saved by improvements in medical technology. So said the authors of "The Health Impact of Resolving Racial Disparities: An Analysis of US Mortality Data," published in the December edition of the American Journal of Public Health.

20 Dec 2004

European market for bone morphogenic proteins in spine fusion

High growth is forecast for novel technologies used either as adjuncts or as alternatives to current surgical procedures for the fusion of spinal vertebrae. Bone morphogenic proteins (BMP) - a new and innovative class of natural growth factors - represent amongst the most exciting of these niches.

20 Dec 2004

Size of myocardial infarct measured using MRI

In animal studies, researchers at Johns Hopkins have effectively used magnetic resonance imaging (MRI) to measure with 94 percent accuracy the size and amount of heart muscle damaged by a heart attack, known in medical terms as a myocardial infarct, or m.i., for short.

20 Dec 2004

Patients with abdominal trauma at risk for intra-abdominal infections following surgery

Patients who undergo surgery for abdominal trauma caused by firearm wounds or by blunt trauma are at risk for developing intra-abdominal infections, and several factors increase that risk, according to a study in the December issue of The Archives of Surgery.

20 Dec 2004