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alpha4 may prove to be useful target for smoking addiction therapies

Nicotine is responsible for more than four million smoking-related deaths each year. Yet people still smoke. Why? One reason is the stranglehold of addiction, started when nicotine enhances the release of a neurotransmitter called dopamine

4 Nov 2004

Hong Kong reports case of H5N1 in dead bird

The Hong Kong Agriculture, Fisheries and Conservation Department (AFCD) has confirmed that a dead Grey Heron found in Lok Ma Chau area was tested positive for H5N1 virus.

4 Nov 2004

The first test in humans of a bioartificial kidney

The first test in humans of a bioartificial kidney offers hope of the device's potential to save the lives of people with acute renal failure, researchers at the University of Michigan Health System report.

4 Nov 2004

Older people are healthier and are living longer

Older people are healthier and more active than ever; They are more likely to stop smoking and to take advantage of health screening and immunisation; Services for older people are improving.

4 Nov 2004

Cellular vehicle delivers drugs directly into cancer cells

Researchers at The University of Texas M. D. Anderson Cancer Center have perfected a delivery system for anticancer treatment that zeroes in on a tumor and becomes part of its supporting tissue.

4 Nov 2004

Trial of new type of drug that attacks amyloid

Neuroscientists at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia will begin a clinical trial testing a new type of drug that attacks amyloid, the protein substance that accumulates in the brains of Alzheimer’s disease patients.

4 Nov 2004

New understanding of the role viruses play in the development of autoimmune diseases

Researchers at the La Jolla Institute for Allergy & Immunology have added a significant milestone to scientific understanding of the role viruses play in the development of autoimmune diseases, such as diabetes.

4 Nov 2004

Ecstasy use down among America's youth

The Substance Abuse and Mental Health Services Administration's (SAMHSA's) just-released 2003 National Survey on Drug Use and Health (NSDUH) reports the number of current ecstasy users decreased between 2002 and 2003, from 676,000 (0.3 percent) to 470,000 (0.2 percent).

4 Nov 2004

Discovery of internal molecular clock that governs the metabolism of sugars and fats within the body

Researchers at the University of Pennsylvania School of Medicine have discovered that components of the internal molecular clock of mammals have an important role in governing the metabolism of sugars and fats within the body.

4 Nov 2004

Pfizer licenses drug from University of Rochester for treatment of hot flashes

The University of Rochester has signed a license agreement with Pfizer which will allow Pfizer to market a specific class of non-hormonal drugs for the treatment of hot flashes associated with menopause.

4 Nov 2004

Quitting smoking can be made easier with long-term comprehensive drug and psychological interventions

People who want to quit smoking have an improved chance of success if they receive long-term comprehensive drug and psychological interventions, according to a new study by UCSF researchers.

4 Nov 2004

Crystal structure of protein AIRs kinase uncovered

Cornell University researchers, who are trying to understand how proteins evolve and function by looking at their structural features, have uncovered the crystal structure of a protein involved in making the building blocks of DNA correctly.

4 Nov 2004

Sensor protein that identifies DNA breaks and activates the p53 cell-death program has been identified

DNA breaks from radiation, toxic chemicals, or other environmental causes occur routinely in cells and, unless promptly and properly repaired, can lead to cancer-causing mutations.

4 Nov 2004

Treatment to control gastroesophageal reflux disease in children found to be ineffective

According to a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, more than 60 percent of the children who received surgical fundoplication to control gastroesophageal reflux disease (GERD) had recurring symptoms of the disease months following surgery.

4 Nov 2004

STAT3 protein could lead to new ways to prevent skin cancer

Scientists at The University of Texas M. D. Anderson Cancer Center have identified a protein that serves as a master regulator of skin cancer - a finding that could lead to new ways to prevent skin cancer before it starts.

4 Nov 2004

Sperm cells grown in laboratory culture

A team of researchers working with cells from mice has overcome a technical barrier and succeeded in growing sperm progenitor cells in laboratory culture.

4 Nov 2004

Gene mutations responsible for causing cataracts in children, identified

Gene mutations responsible for causing cataracts in children have been identified by a team of University of Utah vision researchers. The discovery was reported in a recent issue of The Journal of Medical Genetics.

4 Nov 2004

Researchers identify biomarkers that could lead to more accurate diagnosis of systemic lupus erythematosus

University of Pittsburgh researchers have identified biomarkers that could result in earlier and more accurate diagnosis of systemic lupus erythematosus (SLE), a devastating disease that affects as many as 1.5 million Americans, and occurs 10 to 15 times more frequently in women.

4 Nov 2004

Cyclooxygenase (COX) inhibitors tested in both prevention and treatment clinical trials

Numerous compounds are examined by the National Cancer Institute (NCI) for their potential to prevent or treat cancer. One class of compounds, cyclooxygenase (COX) inhibitors, is currently being tested in both prevention and treatment clinical trials.

4 Nov 2004

Study of infection prevention therapy for premature babies

Whether donated human antibodies can protect premature babies from a common and potentially dangerous bacterial infection is under study at the Medical College of Georgia Children’s Medical Center.

4 Nov 2004