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Newly diagnosed breast cancer patients who test positive for BRCA1 and BRCA2 gene mutations are twice as likely as non-carriers to opt for a double mastectomy

Newly diagnosed breast cancer patients who test positive for BRCA1 and BRCA2 gene mutations are twice as likely as non-carriers to opt for a double mastectomy to reduce the risk of cancer in the opposite breast, according to the first large-scale study evaluating the impact of genetic counseling and testing on breast cancer treatment decisions.

5 Apr 2004

Collaboration to create a series of small molecule drugs leads against a Takeda target

Array BioPharma Inc. today announced the commencement of a drug discovery collaboration with Takeda Chemical Industries, Ltd. to create a series of small molecule drug leads against a Takeda target. This collaboration is in addition to Array's existing research agreement with Takeda that began in 2001.

5 Apr 2004

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information, enabling it to pass from one generation to the next. The grant will fund structural, biochemical and computer studies designed to reveal how the enzyme, DNA polymerase, makes so few mistakes.

5 Apr 2004

The first human case of avian influenza A(H7) in British Columbia

The first human case of avian influenza A(H7) in British Columbia occurred in a person who was involved in culling of infected birds on 13-14 March. On 13 March, he may have been accidentally exposed in the eye. On 16 March, the individual reported conjunctivitis and nasal discharge. Treatment with oseltamavir, an antiviral drug active against influenza A viruses, began on 18 March. On 30 March, Health Canada concluded that this case was caused by avian influenza A(H7). Health Canada informed WHO of this case on 31 March. The patient's symptoms have fully resolved.

5 Apr 2004

Ohio university to get major expansion cancer program

The Ohio State University Board of Trustees today has authorized the preparation of architectural and engineering plans for a possible major expansion of the university’s cancer program.

5 Apr 2004

Research shows giving Tourette Syndrome patients the drug levodopa normalizes brain activity

Scientists have known for years that abnormal activity involving a brain chemical called dopamine is somehow connected to the movements and vocalizations, or tics, associated with Tourette syndrome. Now neuroscience researchers at Washington University School of Medicine in St. Louis have found brain activity in these patients is abnormal during memory tasks, as well.

5 Apr 2004

More evidence needed to link symptoms like tics or behavioral problems to a strep infection

Cephalosporins three times more effective than penicillin

Pediatricians treating a child who has strep throat should reconsider the role of penicillin given that a newer class of antibiotics called cephalosporins are three times more effective, according to a study being published in the April issue of Pediatrics. The findings will spark widespread debate, because they contradict long-established guidelines from the American Academy of Pediatrics, American Heart Association,and World Health Organization.

5 Apr 2004

ULTRACET® Effective And Well Tolerated For Post-Surgical Pain

A new study published in the latest edition of a leading medical journal has shown that treatment with ULTRACET® (37.5 mg tramadol hydrochloride/325 mg acetaminophen tablets) demonstrates similar efficacy and better tolerability than TYLENOL® with Codeine No. 3 when each is compared to placebo.

5 Apr 2004

NeoRx Corporation acquires worldwide rights to platinum-based anti-cancer agent

NeoRx Corporation today announced that it has acquired from AnorMED Inc. the worldwide exclusive rights, excluding Japan, to develop, manufacture and commercialize AMD473, a platinum-based anti-cancer agent. AMD473 has been administered to more than 500 cancer patients in phase I and phase II clinical trials, demonstrating anti-cancer activity in a wide range of tumors and a manageable safety profile. NeoRx expects to initiate clinical studies of AMD473 in one or more cancer indications in the second half of this year.

5 Apr 2004

Penn State Hershey Medical Center awaits arrival of hospital's first sextuplets

The team of Penn State women's health obstetricians and Penn State Children's Hospital neonatologists at Penn State Milton S. Hershey Medical Center are preparing for the arrival of the first set of sextuplets in the medical center's 34-year history.

5 Apr 2004

A simple urine sample could soon be used to predict the complex toxic effects of new drugs

BlueGnome has pioneered the use of statistical signal modelling in the analysis of high throughput experimental data. Its first product BlueFuse for Microarrays uses statistical modelling techniques to eliminate Œnoise‚ generated in microarray experiments, enabling researchers to automatically identify the presence or absence of genes and proteins with a higher level of confidence than is currently possible.

5 Apr 2004

Implantable defibrillator cuts heart attack risk of sudden death by 31%

Researchers at Loyola University Health System, Maywood, Ill., and the University of Rochester Medical Center, Rochester, N.Y., found that the previously demonstrated survival benefit of ICDs following a heart attack can last up to 15 years.

5 Apr 2004

GE Healthcare is giving surgeons breakthrough digital mobile imaging system

Surgeons need to clearly see their subject. In the case of minimally invasive surgery, that can be especially challenging because of the small incision or body opening through which they must work. To combat this difficulty, GE Healthcare is giving surgeons "eyes inside the body," with the OEC® FluoroTrak 9800 Plus, a breakthrough digital mobile imaging system.

5 Apr 2004

Consumer trust in food is high in the United Kingdom, Denmark, and Norway, but low in Italy and Portugal

Consumer trust in food is high in the United Kingdom, Denmark, and Norway, but low in Italy and Portugal and relatively low in Germany. Research also shows that consumers in these countries are most sceptical about meat products, fast-food outlets and food processors.

5 Apr 2004

Functional food, beyond providing a purely nutritional value, may promote health or reduce the risk of disease

Functional food, beyond providing a purely nutritional value, may promote health or reduce the risk of disease. An example is food meant to lower the cholesterol level. During the past few years, the potential benefits posed by functional foods have led to an increased interest by producers and consumers as well as a broader range of such products on the market worldwide.

5 Apr 2004

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

The so-called "memory drugs" used to treat Alzheimer's disease and other causes of dementia also ease or prevent a barrage of troublesome behaviors that affect the majority of patients, ultimately lightening the burden on caregivers, researchers have found. They report their results in the March issue of the American Journal of Psychiatry.

5 Apr 2004

Missed opportunities for addressing HIV testing remain unacceptably high

The researchers, led by Jeffrey Samet, MD, professor of medicine at BUSM and chief of General Internal Medicine at Boston Medical Center (BMC), performed a 10-year retrospective chart review of patients seen at an HIV intake clinic between January 1994 and June 2001 who: 1) tested positive for HIV during the 12 months prior to their presentation at the intake clinic and 2) had one or more encounters recorded in the medical record prior to their HIV positive status.

5 Apr 2004

Professor Michael Banner to head ESRC Genomics Research Forum

Professor Michael Banner will join the University from King's College London, to be Director of the ESRC Genomics Research Forum. Professor Banner is well known in science and public policy arenas. He is currently Chair of the Home Office Animal Procedures Committee, and formerly chaired the Department of Health's CJD Incidents Panel.

5 Apr 2004

Cordis Cardiology receives warning from the U.S. Food and Drug Administration

Cordis Cardiology, a division of Cordis Corporation, a Johnson & Johnson Company, reported today that it received a warning letter from the U.S. Food and Drug Administration (FDA) regarding FDA's observations concerning the Good Manufacturing Practice (GMP) regulations.

5 Apr 2004

Medical News

Newly diagnosed breast cancer patients who test positive for BRCA1 and BRCA2 gene mutations are twice as likely as non-carriers to opt for a double mastectomy

Collaboration to create a series of small molecule drugs leads against a Takeda target

The National Cancer Institute has awarded USC scientists $3.5 million for a study of the enzyme that faithfully copies our genetic information

The first human case of avian influenza A(H7) in British Columbia

Ohio university to get major expansion cancer program

Research shows giving Tourette Syndrome patients the drug levodopa normalizes brain activity

More evidence needed to link symptoms like tics or behavioral problems to a strep infection

Cephalosporins three times more effective than penicillin

ULTRACET® Effective And Well Tolerated For Post-Surgical Pain

NeoRx Corporation acquires worldwide rights to platinum-based anti-cancer agent

Penn State Hershey Medical Center awaits arrival of hospital's first sextuplets

A simple urine sample could soon be used to predict the complex toxic effects of new drugs

Implantable defibrillator cuts heart attack risk of sudden death by 31%

GE Healthcare is giving surgeons breakthrough digital mobile imaging system

Consumer trust in food is high in the United Kingdom, Denmark, and Norway, but low in Italy and Portugal

Functional food, beyond providing a purely nutritional value, may promote health or reduce the risk of disease

Common cholinesterase inhibitor eases behavioral symptoms like agitation, depression, and psychosis in patients

Missed opportunities for addressing HIV testing remain unacceptably high

Professor Michael Banner to head ESRC Genomics Research Forum

Cordis Cardiology receives warning from the U.S. Food and Drug Administration

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Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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