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SARS-CoV-2 evolves differently in the brain, revealing critical insights into viral tropism

Study investigates the evolution of SARS-CoV-2 within the central nervous system (CNS) compared to the lungs in mice, revealing higher viral divergence in the CNS and highlighting the critical role of the furin cleavage site (FCS) in viral tropism and compartmentalization.

27 Aug 2024

Improved IVF success with the Mediterranean diet, study shows

Review highlights that adherence to the Mediterranean diet may improve clinical pregnancy and live birth rates in couples undergoing assisted reproduction, though findings are inconsistent, and more research is needed.

27 Aug 2024

High-dose psilocybin shows promise for depression treatment

Researchers compare the effectiveness and acceptability of oral monotherapy with psychedelics for the treatment of depressive symptoms.

27 Aug 2024

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Researchers have identified an endogenous insulin antagonist, INS-7, in Caenorhabditis elegans that modulates fat loss by inhibiting a gut-to-brain signaling pathway involving the neuropeptide FLP-7.

27 Aug 2024

LSHTM receives £2.8m grant to tackle hidden malaria in India

Researchers at the London School of Hygiene & Tropical Medicine (LSHTM) have been awarded £2.8m to study factors sustaining malaria transmission in an area of India where infections are evading detection.

27 Aug 2024

Autofluorescence imaging improves accuracy of wound debridement

Over 6.5 million Americans experience chronic wounds -; wounds that do not heal after a few months.

27 Aug 2024

Green Heart Louisville Project links more trees to lower inflammation levels

The University of Louisville's groundbreaking Green Heart Louisville Project has found that people living in neighborhoods where the number of trees and shrubs was more than doubled showed lower levels of a blood marker of inflammation than those living outside the planted areas.

27 Aug 2024

NIH funds study on psychedelics' potential to treat methamphetamine addiction

John McCorvy, PhD, Assistant Professor in the Department of Cell Biology, Neurobiology, and Anatomy at the Medical College of Wisconsin (MCW); Adam Halberstadt, PhD, Professor of Psychiatry at the University of California San Diego (UCSD) and Director of the UCSD Center for Psychedelic Research; and Kevin Murnane, PhD, Associate Professor of Pharmacology, Toxicology, and Neuroscience and Director of Basic Science Research for the Louisiana Addiction Research Center at LSU Health Shreveport, were recently awarded a five-year, $2.4 million research grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), to uncover critical insights into how psychedelics could be used as a therapeutic to treat methamphetamine addiction.

27 Aug 2024

Study reveals high failure rate for tubal sterilization as birth control

Tubal sterilization is thought to be a permanent form of birth control and is the most common method of contraception nationally.

27 Aug 2024

NIDDK Catalyst Award funds research on mammary gland's role in metabolic diseases

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Catalyst Award program has awarded a $4 million, five-year grant to Prashant Rajbhandari, PhD, Assistant Professor of Medicine (Endocrinology, Diabetes and Bone Disease) at the Mount Sinai Diabetes, Obesity, and Metabolism Institute, to investigate a new frontier in understanding metabolic diseases like obesity and type 2 diabetes.

27 Aug 2024

Innovative AI tool targets missing data to enhance sepsis risk predictions

A proposed artificial intelligence tool to support clinician decision-making about hospital patients at risk for sepsis has an unusual feature: accounting for its lack of certainty and suggesting what demographic data, vital signs and lab test results it needs to improve its predictive performance.

27 Aug 2024

Urban noise pollution found to have significant negative impact on heart health

Research from two studies in different European cities1,2 highlights that urban noise pollution has a significant negative impact on heart health, according to data presented at ESC Congress 2024.

27 Aug 2024

New insights into γδ T cells could improve treatment for colorectal cancer

The most common form of colorectal cancer, microsatellite-stable colorectal cancer (MSS CRC), can currently only be treated to a limited extent with modern immunotherapies.

27 Aug 2024

Study illuminates CDCA7's role in DNA methylation

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism.

27 Aug 2024

Study reveals how different types of love activate the brain

We use the word 'love' in a bewildering range of contexts -; from sexual adoration to parental love or the love of nature.

27 Aug 2024

Menopause transition linked to changes in blood cholesterol and cardiovascular risk

New research presented at the ESC Congress 2024 in London, UK (30 August - 2 September) shows that women in the menopause transition period show changes in their blood cholesterol profiles which could have an adverse impact on their cardiovascular health.

27 Aug 2024

New ESC atlas data highlights disparities in cardiovascular disease mortality

Cardiovascular disease (CVD) remains the most common cause of death across Europe but while CVD mortality rates are generally decreasing, the decline is much less in middle-income than in high-income countries, according to new data from the European Society of Cardiology (ESC) Atlas of Cardiology, published in the European Heart Journal.

27 Aug 2024