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Researchers uncover metabolic blockade that impedes cancer treatment response

The immune system is a major target for cancer treatments. Immune checkpoint inhibitors and CAR-T cell therapy can dramatically improve outcomes for many cancers. But for about 70% of patients, these therapies don't work.

8 Nov 2024

Thrombotic thrombocytopenic purpura cases after CoronaVac raise concerns over vaccine safety

The COVID-19 pandemic has prompted the rapid development and administration of various vaccines worldwide, with some reports linking these vaccines to immune thrombotic thrombocytopenic purpura (TTP).

8 Nov 2024

SARS-CoV-2 hijacks host proteins to escape immune clearance

Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity.

8 Nov 2024

AI-READI consortium launches groundbreaking diabetes data study

Researchers today (Nov. 8, 2024) are releasing the flagship dataset from an ambitious study of biomarkers and environmental factors that might influence the development of type 2 diabetes.

8 Nov 2024

How physical activity before and after cancer treatment improves outcomes

Physical activity is beneficial before, during and after chemotherapy treatment. New doctoral research has taken a closer look at those who opt out.

8 Nov 2024

Mediterranean diet may reduce type-2 diabetes risk in fatty liver patients

Researchers investigate how Mediterranean diet adherence reduces risk of type-2 diabetes in adults with metabolic dysfunction-associated fatty liver disease.

8 Nov 2024

Advancements in liquid biopsy for detecting pancreatic incidentalomas

In recent research published in eGastroenterology, Dr. J-Matthias Löhr and colleagues provide an in-depth review of diagnostic methods for pancreatic incidentaloma-;incidental findings often detected during imaging scans intended for other conditions.

8 Nov 2024

Circulating tumor cells as a tool for early detection of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a significant global health concern, particularly in regions like the Asia-Pacific, where chronic viral hepatitis and liver diseases contribute to its high incidence and mortality.

8 Nov 2024

Public trust in COVID-19 vaccine science influences vaccine uptake in the US

Researchers investigate how public trust in the science of COVID-19 vaccines has changed in the United States.

8 Nov 2024

Targeting ferroptosis for overcoming chemoresistance in digestive tract tumors

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant tumors worldwide.

8 Nov 2024

Advances in the surgical management of gastroschisis

Gastroschisis, a congenital abdominal wall defect, has transformed from a uniformly fatal condition to one with a 95% survival rate through surgical advancements over the past six decades.

8 Nov 2024

New study links genetic mosaicism to lower Alzheimer’s risk in adults with Down syndrome

Study finds mosaicism in Down syndrome reduces Alzheimer's risk, providing new insights into genetic influences on cognitive decline and dementia progression.

8 Nov 2024

Exploring mouse models for studying liver fibrosis regression

Liver fibrosis is a progressive and potentially reversible condition that results from chronic liver damage, which can be caused by a variety of factors, including metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol abuse, and viral hepatitis.

8 Nov 2024