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Anti-inflammatory cytokine linked to capillary obstruction and cognitive decline in diabetes

Elevated IL-10 in diabetes causes capillary obstruction, linked to cognitive deficits. Blocking IL-10 receptors shows promise for improving brain function.

7 Nov 2024

Research reveals how caterpillar fungus chemical may treat cancer

New research into a chemical produced by a caterpillar fungus that has shown promise as a possible cancer treatment has revealed how it interacts with genes to interrupt cell growth signals.

7 Nov 2024

Hypertension treatment hurts quality of life, especially for women

This research uncovers the complex relationship between blood pressure treatment and mental health, advocating for personalized care to enhance quality of life.

7 Nov 2024

UCD leads major EU project on extracellular vesicles for biomedical research

A major EU project coordinated from UCD is set to push the frontiers of biomedical research by exploring the transformative potential of extracellular vesicles (EVs).

7 Nov 2024

New device improves robot-assisted heart surgery

Robot-assisted heart surgery usually requires an assistant at the operating table to help the surgeon insert the robot arm through a small incision.

7 Nov 2024

Epigenetic silencing of BEND4 unveils new path for PDAC treatment

A novel discovery in the field of pancreatic cancer treatment has been unveiled, revealing the epigenetic silencing of BEND4 as a potential synthetic lethal marker for enhancing the efficacy of ATM inhibitors in pancreatic cancer treatment.

7 Nov 2024

New SCLC biomarkers enable advances in precision medicine approaches

A new research paper was published in Oncotarget's Volume 15 on October 11, 2024, entitled "Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC"

6 Nov 2024

Leritrelvir shows high efficacy against SARS-CoV-2 protease mutations

Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the original wild-type strains to the highly transmissible Omicron variant.

6 Nov 2024

Emerging therapies transform autoimmune hepatitis treatment approaches

Autoimmune hepatitis (AIH) is a chronic, progressive liver disease caused by immune system dysregulation that targets the liver. If untreated, AIH can lead to severe complications, including cirrhosis and liver failure.

6 Nov 2024

New guidelines emphasize non-surgical treatments for uterine fibroids

Uterine fibroids are a common condition that affects up to 80% of women in their lifetime. Nearly half of those women will experience symptoms that affect their quality of life and fertility, including severe pain and anemia.

6 Nov 2024

Electric fans ease heart strain for older adults in humid heat

New collaborative research from the University of Sydney and the Montreal Heart Institute has shown that using a fan in hot and humid weather reduces cardiac strain in older people, contradicting recommendations from the Centers of Disease Control and Prevention in the US.

6 Nov 2024

Five minutes of extra exercise a day could lower blood pressure, study finds

Adding small amounts of exercise into daily routine, such as climbing stairs or cycling to the shops, could help to reduce blood pressure, with just five additional minutes a day estimated to yield improvements, finds a new study from researchers at UCL and the University of Sydney.

6 Nov 2024

Assessing recurrence risk with ctDNA-based MRD detection in NSCLC patients

In operable non-small cell lung cancer (NSCLC), molecular residual disease (MRD) detection via circulating tumor DNA (ctDNA) has emerged as a promising approach to identify individuals at high risk of disease recurrence and potentially guide adjuvant therapy decisions.

6 Nov 2024

The global challenge of weight-related issues in kidney disease

A new nationwide study from Japan spanning a 14 year study period has revealed an increasing trend of overweight and obesity in patients with the incident end-stage kidney disease (ESKD).

6 Nov 2024

Unraveling the psychological impact of COVID-19 on young minds

The COVID-19 pandemic, which began in late 2019, brought immense disruption to individuals and societies worldwide, including children and adolescents. Alongside its immediate physical health impacts, the pandemic had a profound effect on mental health.

6 Nov 2024

Study highlights gaps in measuring sexual orientation and mental health risks

Sexual orientation-;dictated by factors like sexual identity, attraction and behavior-;is challenging to measure comprehensively.

6 Nov 2024

Healthy lifestyle choices can offset genetic risk for brain diseases

Christopher D. Anderson, MD, MSc, chief of the Division of Stroke and Cerebrovascular Diseases at Brigham and Women's Hospital and associate neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is the corresponding author and Jonathan Rosand, MD, MSc, co-founder of the McCance Center for Brain Health and neurologist in the Department of Neurology and Center for Genomic Medicine at Massachusetts General Hospital, is an author of a paper published on November 6, 2024, in Neurology, the medical journal of the American Academy of Neurology, "Health-related behaviors and risk of common age-related brain diseases across severities of genetic risk."

6 Nov 2024

Mount Sinai researchers uncover key process in memory integration

Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience.

6 Nov 2024

Understanding the role of neuroimmune cells in brain health and disease

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

6 Nov 2024

Gaza completes second round of polio vaccination campaign despite conflict barriers

The second round of the polio vaccination campaign in the Gaza Strip was completed yesterday, with an overall 556 774 children under the age of 10 being vaccinated with a second dose of polio vaccine, and 448 425 children between 2- to 10-years-old receiving vitamin A, following the three phases conducted in the last weeks.

6 Nov 2024