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Combination therapy shows promising results in treating stage 3 melanoma

Pre-surgery treatment with the novel drug vidutolimod and the PD-1 checkpoint inhibitor nivolumab led to tumor control in 55% of patients with stage 3 cutaneous melanoma, according to the results of a single-arm phase 2 clinical trial led by the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute (NCI).

1 Nov 2024

Enhanced screening protocols for Candida auris improve hospital infection control

Mount Sinai researchers have enhanced hospital screening protocols for Candida auris, an often-drug-resistant fungal pathogen the Centers for Disease Control and Prevention considers an urgent global health threat.

1 Nov 2024

International experts propose revised Alzheimer's disease definitions

Today, Prof. Howard Feldman presented revised diagnostic criteria for Alzheimer's disease at the Clinical Trials on Alzheimer's Disease (CTAD) Conference in Madrid on behalf of the International Working Group (IWG).

1 Nov 2024

NCCN leaders collaborate to enhance cancer care in Vietnam

As part of ongoing work to define and advance high-quality cancer care globally, leaders from the National Comprehensive Cancer Network (NCCN)-;an alliance of leading cancer centers in the United States-;will be in Vietnam today to collaborate on improving cancer care standards throughout the country.

1 Nov 2024

Study delves into the lives of neurodivergent psychiatrists

Groundbreaking research exploring the experiences of autistic psychiatrists has revealed that psychiatrists who are unaware that they themselves are autistic may fail to recognise the condition in their patients.

1 Nov 2024

Research identifies crucial links between dietary choices and progression of multiple sclerosis

Newly published research in the journal Glia has identified crucial links between dietary choices and the progression of multiple sclerosis (MS).

1 Nov 2024

Innovative imaging technique reveals structure of the thymus

The first 3D images of a whole human thymus have been created using a specialized X-ray technique by researchers from UCL and the Francis Crick Institute.

1 Nov 2024

New stent sensor developed to detect blockages early

Stents to treat various blockages in the human body can themselves become blocked, but a new sensor developed at the University of Michigan for stents that are used in the bile duct may one day help doctors detect and treat stent blockages early, helping keep patients healthier.

1 Nov 2024

Elevated cytokines found in the blood of long COVID sufferers explain heart problems

University of Queensland-led research has found inflammatory markers in the blood of long COVID patients which could explain why many experience ongoing cardiovascular issues.

1 Nov 2024

Polypharmacy linked to negative health outcomes in older adults with Alzheimer's

Polypharmacy, commonly defined as taking five or more medications daily, is a significant health care concern impacting over 30% of older adults.

1 Nov 2024

Critical protein linked to spillover potential of animal viruses

Scientists investigating animal viruses with potential to infect humans have identified a critical protein that could enable spillover of a family of organisms called arteriviruses.

1 Nov 2024

Virtual yoga program shows promise for chronic low back pain relief

Cleveland Clinic researchers found that a 12-week therapeutic virtual yoga program for chronic low back pain can be a feasible, safe and effective treatment option. The findings are published in JAMA Network Open.

1 Nov 2024

Study highlights health benefits of insulating homes against winter cold

During winter, cold indoor temperatures can increase blood pressure, leading to hypertension and an increased risk of cardiovascular diseases (CVDs).

1 Nov 2024

AI provides same-day assessments of antimicrobial resistance in ICUs

Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care – critical to preventing life-threatening sepsis.

1 Nov 2024

Research uncovers new mechanism in protein aggregation linked to Parkinson's disease

A team of researchers at Kumamoto University has uncovered a groundbreaking mechanism in the formation of harmful protein aggregates that lead to neurodegenerative diseases such as Parkinson's Disease.

1 Nov 2024

Study links brain proteins to individual differences in functional connectivity

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale.

1 Nov 2024

New imaging method could transform gene expression research

They say a picture is worth a thousand words. A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024