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Black prostate cancer patients respond better to immunotherapy

Black men with advanced prostate cancer have a greater chance of survival after immunotherapy treatment, at least in part, because of ancestral gene variants in immune responses.

17 Oct 2024

High blood pressure found to increase airway resistance and affect lung function

High blood pressure (hypertension) causes thickening of the blood vessels and hardening of the arteries (arteriosclerosis). A study conducted by Brazilian researchers has shown for the first time that a similar phenomenon occurs in the lungs. High blood pressure hardens the bronchi and increases airway resistance, impairing respiratory capacity.

17 Oct 2024

Metformin found safe for men with type 2 diabetes planning for parenthood

Potential fathers with type 2 diabetes can be reassured that taking the drug metformin is not associated with birth defects in their offspring, concludes a large study of more than 3 million pregnancies published by The BMJ today.

17 Oct 2024

Pediatric brain tumor research takes leap forward with CBTN data

The Gabriella Miller Kids First Data Resource Center (Kids First DRC) announces the addition of the full Children's Brain Tumor Network (CBTN) dataset to the Kids First DRC portal. This significant milestone provides researchers worldwide with unprecedented access to a vast repository of pediatric brain tumor data, paving the way for groundbreaking discoveries and accelerating the development of innovative treatments.

17 Oct 2024

Tissue chips help translate respiratory disease research into clinical applications

Scientists are developing advanced tools to understand and treat neurological symptoms such as brain fog associated with respiratory diseases like influenza.

17 Oct 2024

A deeper look at COVID-19 transmission and fetal health

A new Cleveland Clinic-led study published in The EMBO Journal shows that mild and asymptomatic SARS-CoV-2 infections can trigger immune responses in a pregnant individual that may cause serious inflammatory responses in the developing fetus.

17 Oct 2024

Gut bacteria protect against PFAS-induced kidney harm

New research has revealed that the connection between per- and polyfluoroalkyl substances, or PFAS, and kidney damage may be tied to dysregulation of the gut microbiome, which is made up of bacteria and other microorganisms that live in the digestive tract.

17 Oct 2024

Assessing and addressing IP staffing needs in a pediatric setting

A new paper published today in the American Journal of Infection Control (AJIC) describes efforts at a major children's hospital to assess and fulfill its staffing needs for infection prevention and control, highlighting the challenges of allocating sufficient resources to this important role.

17 Oct 2024

Genetic analysis shows smoking and high BMI increase dementia risk, but education and exercise protect

Mendelian randomization of 400,000 participants reveals smoking, high BMI, and high cholesterol as major genetic risk factors for dementia, while longer education and physical activity reduce risks.

17 Oct 2024

FDA strengthens AI regulation to ensure patient safety and innovation in healthcare

The FDA is adapting regulations to manage AI’s rapid development in healthcare, focusing on patient safety and the life cycle of AI tools. This review emphasizes the need for continuous monitoring to ensure AI performs effectively in clinical settings.

16 Oct 2024

Expanding access to GLP-1 weight-loss drugs could save thousands of lives

Researchers estimate that expanding access to weight-loss drugs could save over 50,000 lives annually, reducing obesity rates and addressing health inequities. Current drug uptake levels prevent far fewer deaths.

16 Oct 2024

Bright night light exposure increases mortality risk, while daylight reduces it

Study reveals that brighter night light exposure and circadian rhythm disruption significantly increase the risk of mortality, particularly from cardiometabolic diseases, while brighter daytime light lowers these risks.

16 Oct 2024

Electronic nudges improve flu vaccination rates in non-diabetic patients but fail to increase uptake in diabetics

Electronic nudges had a small impact on flu vaccine uptake in patients without diabetes but showed no significant effect among diabetic patients, suggesting the need for tailored strategies for this group.

16 Oct 2024

Microplastics accelerate aging and inflammation in fat tissue, increasing risk of chronic disease

Researchers investigate the effects of microplastic exposure on the normal aging and function of adipose tissue.

16 Oct 2024

New protein shows potential for treating systolic heart failure

The heart is a muscle like no other, beating 60 to 100 times per minute on average, around the clock. But when it grows weak, it can lead to serious problems: from debilitating shortness of breath and swelling in the legs and feet, to fluid in the lungs and even death.

16 Oct 2024