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New study confirms brain's waste-clearance pathways in humans

Scientists have long theorized about a network of pathways in the brain that are believed to clear metabolic proteins that would otherwise build up and potentially lead to Alzheimer's and other forms of dementia. But they had never definitively revealed this network in people -; until now.

7 Oct 2024

Weekly injections of anti-obesity medications cost more than surgery

The cost of taking weekly injections of popular anti-obesity medications liraglutide (Saxenda) or semaglutide (Wegovy) exceeds that of metabolic and bariatric surgery in less than a year, according to a recent analysis published in the journal Surgical Endoscopy.

7 Oct 2024

Less is more in octreotide therapy for esophageal variceal hemorrhage

Researchers at the Medical University of South Carolina revealed the need to clarify current treatment guidelines for octreotide therapy following an esophageal variceal hemorrhage in a recent study from the American Journal of Medical Sciences.

7 Oct 2024

Study reveals diverse lengths of luteal phases in healthy women

The current expectation is that every ovulatory menstrual cycle will have a luteal phase (the time from egg released until the next flow) that lasts approximately 14 days.

7 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Early blood test can predict treatment response and survival prospects in metastatic prostate cancer

A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest.

7 Oct 2024

BU professor recognized for excellence in the field of traumatic stress studies

Denise M. Sloan, PhD, professor of psychiatry at Boston University Chobanian & Avedisian School of Medicine and Senior Clinician Investigator, Behavioral Science Division, National Center for PTSD at VA Boston Healthcare System, has received the Robert Laufer, PhD Award for Outstanding Scientific Achievement from the International Society for Traumatic Stress Studies.

7 Oct 2024

Understanding behavioral changes in early dementia

When most people think of dementia, including Alzheimer's disease, they probably think of memory loss first.

7 Oct 2024

Epigenetic testing opens new doors for multiple myeloma treatment

Multiple myeloma is a type of blood cancer that appears mainly after the age of sixty. Its incidence, therefore, increases with the aging of the population.

7 Oct 2024

New insights into immune mechanisms that prevent cancer metastasis

Metastatic disease-;when cancer spreads from the primary tumor to other parts of the body-;is the cause of most cancer deaths.

7 Oct 2024

US adults face worse midlife health compared to British counterparts

A study reveals poorer cardiometabolic health in middle-aged Americans compared to Brits, highlighting the impact of socioeconomic status on health outcomes.

7 Oct 2024

When CDK12/13 stalls, healthy prostate cells take a malignant turn

CDK12 is established as a tumor suppressor in prostate cancer, with its loss driving aggressive disease and creating vulnerabilities for targeted therapies.

7 Oct 2024

Bruker Introduces Innovative Neuroscience Research Solution with High-Speed OptoVolt Voltage Imaging

New multiphoton microscopy module enables millisecond neural event imaging at single neuron resolution.

From Bruker Nano Surfaces and Metrology 7 Oct 2024

New cell therapy offers effective treatment for patients with T-cell acute lymphoblastic leukemia

A new cell therapy, targeting CD7 on leukaemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukaemia (T-ALL) who have exhausted all standard treatment options.

7 Oct 2024

One-dose HPV vaccination could eliminate cervical cancer in Canada

Canadian vaccination programs could switch to a 1-dose gender-neutral human papillomavirus (HPV) vaccination approach and eliminate cervical cancer, suggests new modeling in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.240787.

7 Oct 2024

New research highlights the impact of stigma on health equity

A new article published in Nature Reviews Disease Primers underscores the profound role that stigma can play in health care -- and how addressing stigma-related barriers can significantly improve health outcomes for individuals and communities around the world.

7 Oct 2024

Antigenic mapping sheds light on SARS-CoV-2 immunity differences

A person's immune response to variants of SARS-CoV-2, the virus that causes COVID-19, depends on their previous exposure - and differences in the focus of immune responses will help scientists understand how to optimise vaccines in the future to provide broad protection.

7 Oct 2024