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  • Cell Metabolism Assays
    Life Sciences - 26 Feb 2019
    Many different assays are used to detect and measure cellular metabolism, depending on the metabolite being investigated.
  • Melanin Production Pathway
    Life Sciences - 26 Feb 2019
    Melanin is synthesised in cytoplasmic organelles called melanosomes, which reside in skin cells and hair follicles called melanocytes. This process is known as melanogenesis.
  • Micro-PET Principles, Strengths, and Weaknesses
    Life Sciences - 26 Feb 2019
    Positron emission tomography (PET) is a nuclear imaging tool for molecular and functional imaging of biological processes. While functional imaging is used to monitor parameters such as perfusion and...
  • Validating Biomarkers in Targeted Metabolomics
    Life Sciences - 26 Feb 2019
    Recently, metabolic profiling has attracted interest for the validation of biomarkers which can be used to discover the underlying mechanism of a disease.
  • Applications of the Expanded Genetic Code
    Life Sciences - 26 Feb 2019
    The genetic code consists of 64 triplets of nucleotides called codons. With the exception of three codons, each codon encodes for at least one of the 20 canonical amino acids and most of the amino...
  • MPSS and SAGE Compared
    Life Sciences - 26 Feb 2019
    MPSS and SAGE are commonly used to quantify gene expression. Both can be used without prior sequence information and have similar applications.
  • Sanger Sequencing and Next-Generation Sequencing Compared
    Life Sciences - 26 Feb 2019
    Currently, the two most popular methods of DNA sequencing are Sanger sequencing and next generation sequencing (NGS). View a comparison of each method here.
  • The i-motif in DNA
    Life Sciences - 26 Feb 2019
    Cytosine rich DNA sequences can fold into a structure called an i-motif. These structures typically appear in non-coding or promoter regions on DNA.
  • Role of Transcription Factors
    Life Sciences - 26 Feb 2019
    Transcription refers to the creation of a complimentary strand of RNA copied from a DNA sequence. This results in the formation of messenger RNA (mRNA), which is used to synthesize a protein via...
  • CRISPR Interference (CRISPRi) for Gene Suppression
    Life Sciences - 26 Feb 2019
    CRISPR (cluster of regularly interspaced palindromic repeats) are sequences found in approximately 50% of bacteria and approximately 90% of archaea, providing adaptive immunity against viral...

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