Medical Thought Leaders

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News Medical's "Thought Leaders" series is a selection of articles written by national and international experts and trusted advisers in health and medicine. All the articles are written by experts who have been invited as recognised leaders in their fields to provide a "state of the art" contribution.

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Colorectal cancer is a malignant neoplasm affecting the large bowel and the rectum mainly after the 5th decade of life and representing the second cause of death for cancer in western countries (the third in women). In about 15-20% of patients there is an inherited predisposition.

29 Jan 2013

Post-traumatic stress disorder (PTSD) in children: an interview with Donna Gillies

Children with PTSD suffer significant distress or negative impacts on their daily lives. Estimates of the prevalence of PTSD in children and adolescents experiencing trauma are generally very high, at 30% to 40%.

28 Jan 2013

Subsidised antimalarial drugs: an interview with Kara Hanson

Artemisinin-based combination therapies (ACTs) are the currently recommended drugs for treating malaria. However, they are expensive, which limits their affordability. This means that people with malaria are likely to buy cheaper, less effective antimalarials such as chloroquine and sulphadoxine-pyrimethamine; or to simply buy painkillers and antipyretics.

25 Jan 2013

Sex, condoms and lubricants: an interview with Dr Debby Herbenick

Condoms and lubricants are widely used by both women and men and so they are part of many people’s sexual experiences. They are used for both pleasure-related reasons as well as, in the case of lubricants, comfort and making sex easier for people. The use of condoms of course reduces the risk of pregnancy or infection.

23 Jan 2013

Physical activity policies: an interview with Dr Nick Cavill

Our bodies were designed to be active. The human body is not meant to spend long periods of time sitting but that’s what our modern lives have led us to do. The result has been the increase in obesity seen across the world, and up to 20 other conditions including cardiovascular disease and diabetes.

22 Jan 2013

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Itch was actually defined by a German physician more than 350 years ago. His name was Samuel Hafenreffer. He defined itch as an unpleasant sensation that makes people want to scratch. You probably think this is a very simple definition but itch is really a very complex sensory modality.

21 Jan 2013

Miscarriage and molecular signals: an interview with Prof Brosens and Prof Quenby

Miscarriage is defined as the spontaneous loss of pregnancy before the baby reaches viability. Besides the physical trauma, miscarriage causes considerable anxiety, stress, and depression.

17 Jan 2013

Malaria control: an interview with Dr Jo Lines

Malaria is a tropical, mosquito-borne disease. It is found all over the tropics, in every continent but diminished now a great deal in most of Latin America, most of Asia. Still 90% of the world’s deaths due to malaria – are in Africa and most of them are in young children in Africa.

16 Jan 2013

Dementia care services: an interview with Sue McLean

The term 'dementia' is used to describe symptoms that occur when the brain is affected by specific diseases and conditions, such as Alzheimer’s disease, vascular dementia, Lewy Bodies or Korsakoff’s syndrome.

From Community Integrated Care 15 Jan 2013

Bionic devices: an interview with Dr Rylie Green

Bionic devices are implants which replace biological functions which have been lost due to nerve damage. They use electrical signals to stimulate the remaining nerve cells following disease or injury. Although the term bionic was only coined in the late 1950s, the earliest bionic devices were cardiac pacemakers, developed in the early 1900s. However the first commercial implantable units were not available until the 1950s.

14 Jan 2013

Flusurvey: an interview with Dr Alma Adler

Flusurvey is an online system of tracking influenza across the UK. We are linked to other flu surveys across Europe, so there are about 12 flu surveys across Europe in total.

9 Jan 2013

Industry sponsored drug and device studies: an interview with Professor Lisa Bero

Our review included analyses of drug and device studies conducted in humans. The drugs or devices could be compared to placebo or sham treatments, or other effective treatments. The drugs and devices examined for this review are used for a wide variety of clinical conditions, including cardiovascular and psychiatric diseases.

7 Jan 2013

Parkinson’s: an interview with Steve Ford, CEO of Parkinson’s UK

Parkinson’s disease is a neurological condition that is caused when brain cells, that produce the chemical messenger dopamine, start to die.

24 Dec 2012

Exercise and mental health: an interview with Professor Nanette Mutrie

Perhaps we should first of all clear up the definition of exercise. In public health terms it is more common to use the phrase ‘physical activity’ because this phrase encompasses all kinds of movement- indeed anything we do above sitting and resting levels.

21 Dec 2012

Arthritis, rheumatism and total joint arthroplasty: an interview with Dr Ravi and Dr Hawker

Arthritis translates to “joint inflammation.” The most common form of arthritis is osteoarthritis (OA), which affects 12-15% of North Americans over the age of 60, and will increase in prevalence as our population ages.

19 Dec 2012

Jagaricin and antifungal drugs: an interview with Prof Christian Hertweck

Most people have already experienced a fungal infection (mycosis) of the outer layer of the skin, athlete’s foot or ringworm. Whereas such infections may be cumbersome and often difficult to cure, usually they are not dangerous. However, in cases where a fungus causes a systemic infection, this is, it infects internal organs such as lungs or brain, the infection may turn into a life-threatening disease. Of course, only pathogenic fungi cause problems and the degree of virulence varies.

18 Dec 2012

Alcohol and antibiotics: an interview with Dr Randall

Contrary to popular belief, there are only a handful of antibiotics that can interact with alcohol to cause unpleasant effects. The two main antibiotics you should definitely avoid drinking alcohol with are metronidazole (brand names include Flagyl) and tinidazole (brand names include Fasigyn).

18 Dec 2012

Osteoporosis screening: an interview with Professor Cyrus Cooper

Osteoporosis is defined as a reduction in bone mass coupled with micro-architectural deterioration of bone tissue which predisposes to fractures. Osteoporosis manifests through an increased risk of fracture, and age-related fractures are a major public health problem.

17 Dec 2012

Dyslipidaemia: an interview with Prof. Peter Kokkinos

Dyslipidemia is defined as abnormal levels of blood lipids (fats) and cholesterol. The most common dyslipidaemias are high blood cholesterol (Total Cholesterol) and triglyceride levels, high levels of low-density lipoprotein (LDL) cholesterol (‘bad’ cholesterol) and low levels of high-density lipoprotein (HDL) cholesterol (‘good’ cholesterol).

17 Dec 2012

Malaria vaccine trial: an interview with Professor Sir Brian Greenwood

Malaria is an infection caused by a parasite called plasmodium, which is transmitted from person to person by females of some species of mosquito. It is primarily a disease of tropical countries.

14 Dec 2012