Aug 5 2008
According to U.S. researchers, during a given week, one in ten children uses one or more cough and cold medications.
The researchers say in view of concerns regarding the potential harmful effects and lack of evidence proving that these medications are effective in young children, the numbers are a concern.
Lead author Dr. Louis Vernacchio, an assistant professor of epidemiology and pediatrics at Boston University School of Medicine says the common use of cough and cold medications among young children is especially noteworthy and the number of children using such medications is striking.
The researchers from the Slone Epidemiology Center say though pediatric cough and cold medications are widely marketed in the U.S. surprisingly little is known about just how often they are used in children.
They say their information is especially important in light of recent revelations that cough and cold medications are responsible for serious adverse events and even deaths among children.
The researchers analysed data between 1999 and 2006 from the Slone Survey, a national telephone survey of medication use in a representative sample of the U.S. population, in order to define the frequency and patterns of use.
They considered all oral medicines that are approved by the FDA to treat children's coughs and colds and found that in a given week, at least one cough and cold medication was used by 10.1 percent of U.S. children.
In terms of active ingredients contained in these medications, exposure was highest to decongestants and antihistamines (6.3 percent each), followed by anti-cough ingredients (4.1 percent) and expectorants (1.5 percent).
Exposures to cough and cold medications was highest among 2 to 5 year olds and children under 2 years of age.
Among all the products used, 64.2 percent contained more than one active ingredient. The most commonly used product types were single-ingredient antihistamines, antihistamine/decongestant combinations and antihistamine/decongestant/anti-cough combinations.
The researchers also found the use of cough and cold medications declined from 12.3 percent in 1999-2000 to 8.4 percent in 2005-2006.
The research appears in the August issue of the journal Pediatrics.