Axela introduces dotLab Amine Reactive Sensor

Mar 4 2009

Axela Inc has introduced the dotLab Amine Reactive Sensor for stable covalent coupling of affinity reagents such as antibodies for use with the Axela dotLab System.

Now researchers in the basic and clinical sciences and protein production have additional tools for immunoassay design and interaction experiments to complement the original dotLab Avidin Sensors. The newly released Amine Reactive Sensor directly links capture species covalently, thereby eliminating the need for offline conjugation and reducing capture protein requirements 50-fold. This is especially advantageous when only small quantities of reagent are available or when screening a number of candidates prior to undertaking biotinylation. In addition, Amine Reactive Sensors are compatible with regeneration for increased throughput or rapid comparative experiments. The sensor’s lidless format even makes sample recovery possible for offline Mass Spectrometry analysis.

Customers have a choice of ordering from different Amine Reactive Sensor formats:

Sensor Kit – 12 sensors and a tubing set
Starter Kit – 12 sensors, tubing set, model assay test reagents and buffers
Activation Kit - activation reagents and buffers for amine directed coupling

The dotLab System employs a novel technology for performing immunoassays and the real-time study of protein interactions. The instrument automatically delivers samples and reagents to an inexpensive, disposable dotLab Sensor where binding events are quantitatively measured in real time. The system expands the utility of traditional immunoassays and makes unique categories of diagnostic markers accessible for study.