New data for BMS747158 to be featured in oral presentation at ACC Annual Scientific Session 2010

Mar 10 2010

Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic imaging, today announced that new data for BMS747158, the company’s novel drug candidate in clinical development as a Positron Emission Tomography (PET) perfusion imaging agent, will be featured in an oral presentation at the American College of Cardiology 59^th Annual Scientific Session taking place March 14-16, 2010 in Atlanta. BMS747158 is now known by the generic name flurpiridaz F 18. In addition, new data on LMI1195, the company’s innovative PET imaging agent in clinical studies for heart failure, will be highlighted in a poster presentation.

“Lantheus Medical Imaging is committed to developing a new generation of diagnostic products that cardiologists can use to advance patient care.”

The oral presentation will feature new data from a single center comparing flurpiridaz F 18, currently in Phase 2 clinical trials, with rest-stress SPECT imaging for the detection and evaluation of coronary artery disease (CAD). Jamshid Maddahi, M.D., F.A.C.C., Professor of Molecular and Medical Pharmacology (Nuclear Medicine) and Medicine (Cardiology) at the David Geffen School of Medicine at UCLA and the Lead Principal Investigator of the study, will present these findings from his center. Preclinical data for LMI1195, a novel F-18 small molecule tracer for heart failure imaging currently in Phase 1 clinical trials, will be presented by Ming Yu, M.D., Ph.D., Sr. Research Investigator, Lantheus Medical Imaging, Inc.

“We are pleased that the American College of Cardiology has chosen to feature two of our pipeline products at its upcoming annual meeting. These agents have the potential to improve the evaluation of coronary artery disease and heart failure, both areas of significant unmet medical need. We believe that PET technology, combined with our F-18 labeled tracers, could provide significant advancements in diagnostic imaging for better disease detection and management in patients with cardiovascular disease,” said Don Kiepert, President and Chief Executive Officer, Lantheus Medical Imaging, Inc. “Lantheus Medical Imaging is committed to developing a new generation of diagnostic products that cardiologists can use to advance patient care.”

Details for the oral and poster presentations are as follows:

Presentation Date/Time: Tuesday, March 16, 8:00-8:15 a.m. (ET)

Abstract Title: Comparison of F-18 Labeled BMS747158 PET and Tc-99m Labeled SPECT Myocardial Perfusion Imaging for Detection and Evaluation of Coronary Artery Disease (Presentation # 0917-03)

Topic: Positron Emission Tomography: Ischemia and Microvascular Function

Presenter: Jamshid Maddahi, M.D., F.A.C.C., Professor of Molecular and Medical Pharmacology (Nuclear Medicine) and Medicine (Cardiology) at the David Geffen School of Medicine at UCLA

Session/Location: ACC Oral Contributions, Georgia World Congress Center, Room B403

Presentation Date/Time: Monday, March 15, 3:30-4:30 p.m. (ET)

Abstract Title: LMI1195: A New 18F Benzylguanidine Analog for PET Cardiac Sympathetic Neuronal Imaging (Presentation # 1202-226)

Topic: SPECT: Risk Stratification and New Agents

Presenter: Ming Yu, M.D., Ph.D., Sr. Research Investigator, Lantheus Medical Imaging, Inc.

Session/Location: ACC Poster Contributions, Georgia World Congress Center, Hall B5

SOURCE Lantheus Medical Imaging, Inc.