Lexicon Pharmaceuticals to present Phase 2 study results of LX1031 for non-constipating IBS at DDW 2010

Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that the company will be giving poster and oral presentations on results from its Phase 2 clinical study with LX1031 in patients with non-constipating irritable bowel syndrome (IBS) at Digestive Disease Week (DDW) 2010 in New Orleans, Louisiana. Results from the study, in which LX1031 produced improvements in IBS symptoms, will be presented during the poster session on Sunday, May 2, 2010 from 12 p.m. to 2 p.m. Central Time and the oral presentation on Wednesday, May 5, 2010 at 9:30 a.m. CT (session start time is 8:30 a.m. CT).

DDW is the world's largest gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Every year it attracts approximately 16,000 physicians, researchers and academics from around the world.

Clinical development of LX1031 is being funded through a product development collaboration with Symphony Capital Partners, L.P. and its co-investors.

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