Forest, Nycomed to present data from six roflumilast posters at ATS International Conference

May 10 2010

Forest Laboratories, Inc. (NYSE: FRX) and Nycomed today announced that they will present data from six roflumilast posters during the American Thoracic Society (ATS) International Conference being held in New Orleans, LA, May 14 through May 19, 2010. Roflumilast is an investigational anti-inflammatory, oral medication for the treatment of Chronic Obstructive Pulmonary Disease (COPD) associated with chronic bronchitis in patients at risk of exacerbations. Included in the poster presentations are additional results from the 12-month and 6-month roflumilast studies previously published in The Lancet.

The scheduled times and titles of presentations are:

• Roflumilast and its active metabolite inhibit LPS-induced cytokine production from human lung macrophages by a PGE2-dependent mechanism: poster (D7) available on Sunday, May 16, 8:15 am - 4:00 pm CDT, with presentation by A. Buenestado, PhD, 10:45 am - 12:30 pm
• Efficacy of roflumilast in patients receiving concomitant treatments for chronic obstructive pulmonary disease over 12 months: poster (F72) available on Tuesday, May 18, 8:15 am - 4:00 pm CDT, with presentation by N.A. Hanania, MD, MS, 10:45 am - 12:30 pm
• Time course and reversibility of weight decrease with roflumilast, a PDE4 inhibitor: poster (F78) available on Tuesday, May 18, 8:15 am - 4:00 pm CDT, with presentation by F.J. Martinez, MD, MS, 10:45 am - 12:30 pm
• Effects of roflumilast, a PDE4 inhibitor, on body composition in chronic obstructive pulmonary disease: poster (B64) available on Tuesday, May 18, 8:15 am - 4:00 pm CDT, with presentation by E.F.M. Wouters, MD, PhD, 10:45 am - 12:30 pm
• Effects of roflumilast, a PDE4 inhibitor, on glucose homeostasis in patients with treatment-naïve diabetes: poster (B62) available on Tuesday, May 18, 8:15 am - 4:00 pm CDT, with presentation by E.F.M. Wouters, MD, PhD, 10:45 am - 12:30 pm
• Roflumilast N-oxide partially prevents the loss of ciliated human airway epithelial cells secondary to incubation with cigarette smoke extracts in vitro: poster (B68) available on Tuesday, May 18, 8:15 am - 4:00 pm CDT, with presentation by J. Milara, PhD, 10:45 am - 12:30 pm