Threshold Pharmaceuticals commences TH-302 Phase 1 clinical trial in patients with advanced leukemias

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Jun 29 2010

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Threshold Pharmaceuticals, Inc. (Nasdaq:THLD), today announced that it has initiated a Phase 1 clinical trial of TH-302 in patients with advanced leukemias. TH-302 is a proprietary Hypoxia-Activated Prodrug (HAP) that specifically targets tumor hypoxia.

"There is an enduring unmet need for effective new treatments for patients with refractory hematological malignancies," said Dr. Deborah Thomas, M.D., Associate Professor in the Department of Leukemia at MD Anderson Cancer Center. "There is a strong preclinical rationale to evaluate TH-302 in this patient population and we are excited to be leading this innovative clinical trial."

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Threshold Pharmaceuticals

Posted in: Drug Trial News | Medical Condition News

Tags: Acute Lymphoblastic Leukemia, Biotechnology, Bone, Bone Marrow, Cancer, Cell, Chronic Lymphocytic Leukemia, Clinical Trial, Doxorubicin, Gemcitabine, Hypoxia, Leukemia, Lung Cancer, Lymphoma, Multiple Myeloma, Non-Small Cell Lung Cancer, Pancreatic Cancer, Pharmaceuticals, Preclinical, Prostate Cancer, Small Cell Lung Cancer, Soft Tissue Sarcoma, Tumor

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