Shire announces tender offer results

Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announces that shareholders of Movetis NV have tendered 99.18% of the shares of Movetis (Euronext Brussels: MOVE) during the initial acceptance period of the tender offer which closed on September 27, 2010. The shares tendered into the tender offer are expected to be settled on October 12, 2010.

In addition, warrant holders of Movetis have agreed to tender 727,911 new shares to be issued on the settlement date following the conditional exercise of warrants.

Accordingly, Shire Holdings Luxembourg S.a r.l. (a subsidiary of Shire plc) will own 99.21% of the outstanding shares of Movetis on the settlement date of the tender offer.

Squeeze-Out Procedure

Shire has decided to proceed with a squeeze-out of those shares not tendered to the offer in accordance with applicable Belgian legislation. In this regard, an additional tender offer period will open, on the same terms, on October 12, 2010 and close on November 2, 2010 at 4 pm CET.

Shares tendered into the additional tender offer are expected to be settled on November 8, 2010. Shares and warrants not tendered to the additional tender offer shall be deemed transferred to Shire Holdings Luxembourg S.a r.l. by operation of law on November 8, 2010. Payment of the offer price for shares and warrants not tendered to the additional tender offer will be deposited with the Deposito-en Consignatiekas/Caisse des Depots et Consignations in Belgium.

At the close of the reopened tender offer, the shares in Movetis will be delisted from Euronext Brussels. The last trading day will therefore be November 2, 2010.

Shire's offer is EUR19 in cash for each outstanding Movetis share.

The prospectus relating to the tender offer and the squeeze-out is available at no cost at the counters of the Receiving and Paying Agents in Belgium The Royal Bank of Scotland N.V. or by phone (+3120/4643707), KBC Securities NV, KBC Bank NV, CBC Banque SA or by phone 03/283 29 70 (KBC telecenter) or 0800/92 020 (CBC Banque). An electronic version of the prospectus is available on the following websites: http://www.kbcsecurities.be, http://www.kbc.be, http://www.cbcbanque.be and http://www.shire.com.

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