Glybera gene therapy reduces pancreatitis risk in Lipoprotein Lipase Deficiency patients

Data Presented at the 79^thEuropean Atherosclerosis Society Meeting

Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, today released data showing that its gene therapy Glybera® (alipogene tiparvovec) significantly reduces the risk of pancreatitis in patients with Lipoprotein Lipase Deficiency (LPLD). Pancreatitis, or inflammation of the pancreas, is a major clinical symptom of LPLD. It causes severe abdominal pain and often leads to hospitalization of patients as well as other complications such as diabetes and early atherosclerosis. Data were presented at the 79^th European Atherosclerosis Society Meeting (26-29 June 2011, Gothenburg, Sweden).

"These data demonstrate the dramatic impact Glybera can have in the lives of LPLD patients. Pancreatitis is a debilitating and extremely painful condition. Many patients end up in the hospital emergency room and try to control the pain by any means," explained Janneke de Wal, Director of Global Sales & Marketing at AMT. "By reducing the incidence of pancreatitis episodes, Glybera has the potential to help "normalize" the day to day lives of patients affected by this disease and prevent the often frequent trips to hospital."