New data from Bayer's investigational oncology compounds to be presented at ECCO-ESMO congress

Bayer HealthCareSep 13 2011

Bayer HealthCare announced today that the company will present data on several of its investigational compounds at the 2011 European Multidisciplinary Cancer Congress (ECCO-ESMO), September 23-27, 2011, in Stockholm, Sweden. These presentations, including the pivotal Phase III ALSYMPCA (ALpharadin in SYMptomatic Prostate CAncer) data evaluating radium-223 chloride in patients with castration-resistant prostate cancer (CRPC), will highlight the potential of Bayer's growing oncology pipeline.

"We look forward to presenting the complete Phase III data on radium-223 chloride for the first time following the positive results from the ALSYMPCA interim analysis released earlier this year," said Kemal Malik, MD, Head of Global Development and member of the Bayer HealthCare Executive Committee. "These data, along with other presentations from our oncology pipeline, serve to demonstrate Bayer's commitment in cancer."

Studies evaluating Bayer's investigational oncology compounds being presented at ECCO-ESMO include:

Radium-223 Chloride

• LATE BREAKING ABSTRACT: Overall Survival Benefit of Radium-223 Chloride (Alpharadin™) in the Treatment of Patients with Symptomatic Bone Metastases in Castration-resistant Prostate Cancer (CRPC): a Phase III Randomized Trial (ALSYMPCA)
  • Presidential Session I: Best and Late Breaking Abstracts
  • Saturday, September 24, 2011, 2:35pm CEST, Hall A1

A separate 24-month safety analysis from Phase II studies of radium-223 chloride will be presented at the meeting as a poster discussion (Abstract #7008, Poster Discussion Session: Genitourinary Malignancies – Prostate Cancer, Monday, September 26, 2011, 11:00am-12:00pm CEST, Hall A8).

Regorafenib (BAY 73-4506)

• Phase II Trial of the Oral Multikinase Inhibitor Regorafenib (BAY 73-4506) as First-line Therapy in Patients With Metastatic or Unresectable Renal Cell Carcinoma (RCC)       
• Abstract # 7141, Poster Session: Genitourinary Malignancies - Other
• Sunday, September 25, 2011, 2:00-4:30pm CEST, Poster Area  
• Phase II Safety Study of the Oral Multikinase Inhibitor Regorafenib (BAY 73-4506) as Second-line Therapy in Patients With Hepatocellular Carcinoma
• Abstract # 6576, Poster Session: Gastrointestinal Malignancies - Non-colorectal Cancer
• Monday, September 26, 2011, 9:30am-12:00pm CEST, Poster Area