One in six prescriptions may carry a medication error: GMC survey finds

A new study has found that more than one in six patients who are put on medication after seeing their GP are given a prescription containing an error. The study comes from the General Medical Council.

The GMC regulates doctors. It found that over the course of a year, one in 20 prescription items had some sort of error or monitoring of the patient taking the drug was not good enough – this usually involved drugs where regular blood tests were needed to ensure the drug was not causing other problems. Thus, they note that of the 900 million prescriptions in England every year, this amount to 45 million errors. There were also more errors among people over 75, who are often on more drugs.

The study adds that most of the errors fell into the category of oversights rather than mistakes, such as the GP failing to write down how often the patient should take their pills or the correct dose. But in one in 550 items – equating to 1.6 million prescription items across England – the error was considered severe. “Two were errors where patients had a previous record of an allergy to a drug and were prescribed that drug,” said Professor Tony Avery of the University of Nottingham's medical school, who led the research. One was penicillin and the other was an antiviral drug, he said. The allergy should have been flagged up by the practice's computer system. Further it was found that often there was no monitoring. For example those taking blood-thinning drug warfarin need such monitoring.

Only one serious adverse reaction was detected among the 15 GP practices from three areas of England selected as representative of the country, which had 1,777 patients among them. An older patient, who was prescribed non-steroidal anti-inflammatory drugs (NSAIDs), which include ibuprofen) was admitted to hospital with stomach bleeding – a known issue with the drugs.

GMC did the a similar survey of hospitals. There they noted a prescribing error rate of around 8%. The error rate in GP surgeries is lower, at 5% of items prescribed, and the causes appear to have far more to do with GP-patient interaction. “It is quite clear GPs take their prescribing very seriously,” said Avery. But one of the problems is distraction. Prescribing takes place at the end of the consultation, when time is running out and sometimes the patient has started to talk about another complaint or problem.

Professor Sir Peter Rubin, chair of the GMC, said he will be talking to the department of health, the Royal College of GPs and the Care Quality Commission about ways of improving prescribing. “GPs are typically very busy, so we have to ensure they can give prescribing the priority it needs,” he said. Effective computer systems could help pick up errors and ensure monitoring and pharmacists could give valuable support and oversight, he added.

Human error and not a lack of understanding or knowledge was behind most mistakes, the study said. Extending the average GP consultation from 13 minutes to 15 and better training in safety would help, lead author, Prof Tony Avery, of Nottingham University, said. Pharmacists and GP receptionists can also help by carrying out medicine reviews and checking monitoring arrangements.

Dr John Holden of the Medical and Dental Defence Union of Scotland said, “MDDUS has dealt with a number of cases where doctors have faced fitness to practise proceedings regarding prescribing errors, many of which could have been easily avoided. In one case a doctor prescribed methotrexate daily instead of weekly to an arthritis patient who became seriously unwell and required hospital treatment.” He added, “Other complaints relate to drugs that require close monitoring such as anti-depressants being issued as repeat prescriptions without sufficient patient follow-up and monitoring. These errors could have been avoided if robust prescribing systems had been in place to monitor patients and ensure dosage information is accurate.”

Martin Astbury, president of the Royal Pharmaceutical Society, said, “Prescribing errors are common but the number of mistakes could be reduced by up to 50 per cent if GPs introduced an in-house pharmacist-led support scheme. We are calling for every GP practice to have a pharmacist on the premises dedicated to patient safety.”

Dr Clare Gerada, chairman of council at the Royal College of GPs, said, “There are over one million patient consultations in general practice every day across the UK, and this report demonstrates that in 95 per cent of cases GPs prescribe safely and effectively in the best interests of their patients.”

The health secretary, Andrew Lansley, said, “Patient safety is paramount. The vast majority of prescriptions are checked by community pharmacists, who spot and put right any errors when they are dispensed. Patients can be confident that the medicines they receive are safe and appropriate. We have worked to improve and increase the training medical students receive in prescribing skills, and we are working with GPs to see how we can best support them to work with pharmacists and improve the safety and effectiveness of prescribing. We will continue to work with pharmacists and GPs to reduce prescribing errors and make the best use of medicines.”

Dr. Ananya Mandal

Written by

Dr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.

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