Jun 4 2013
Debiopharm Group™ (Debiopharm), a Swiss-based global biopharmaceutical group of companies with a focus on the development of prescription drugs that target unmet medical needs, including oncology and companion diagnostics, today announced it treated its first patients in a phase I study of Debio 1143 combined with Carboplatin and Paclitaxel in patients with squamous non-small cell lung cancer (NSCLC), platinum-refractory ovarian cancer, and basal-like/claudin low triple negative breast cancer.
The aim of this study is to evaluate the safety and tolerability of Debio 1143, a small molecule neutralizing inhibitors of Apoptosis Protein (IAP), in combination with Carboplatin and Paclitaxel, to determine the maximum tolerated dose (MTD) and to establish dosing for further expansion phase.
"There are numerous cancers that are or become relatively insensitive to chemotherapy and other current treatments," said Rolland-Yves Mauvernay, President and founder of Debiopharm Group™. "We are happy about the initiation of this trial and hope to deliver a new tool that will bridge the gap in the treatment of these types of cancers."
SOURCE The Debiopharm Group
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