Array BioPharma Inc. (NASDAQ: ARRY) today announced presentations on encorafenib, binimetinib and selumetinib (licensed to AstraZeneca) at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, which will be held May 29 – June 2, 2015 in Chicago, Illinois. These three products are currently advancing in a total of 6 pivotal trials, with top-line results expected in 2015 from both the NEMO (binimetinib monotherapy in NRAS mutant melanoma patients) and SUMIT (selumetinib with dacarbazine in uveal melanoma patients) Phase 3 trials.
Ron Squarer, Chief Executive Officer of Array, noted, "We are encouraged to see eight ASCO abstracts reporting clinical results from Array-invented BRAF, MEK and HER2 drugs, while we await readouts later this year from two pivotal trials, NEMO and SUMIT."
The following is a summary of the presentations that will be given at ASCO:
ORAL PRESENTATIONS
POSTER PRESENTATIONS
Trials in Progress posters will also showcase the trial designs for the Phase 3 binimetinib trial in low-grade serous ovarian cancer (MILO), two filanesib Phase 2 trials in multiple myeloma (combination with carfilzomib, and single agent (AfFIRM), two ipatasertib (GDC-0068) Phase 2 trials in breast cancer (FAIRLANE and LOTUS) and the LOXO-101 Phase 1 trial in solid tumors.