Advion, Inc., a leading systems and consumables developer for the life sciences industry, announced it has released Peak Express software, available with the expression compact mass spectrometer (CMS). The software introduces a patent-pending breakthrough in novel mass spectrum display, available exclusively in the Advion Peak Express software suite: The Delta Spectrum (ΔS), which looks beyond chemical noise and automatically detects even the smallest peaks without the user needing to know the product ion mass in advance.
Advion’s Peak Express software amplifies detection capabilities, allowing a user to find adducts, dimers, fragments, side-reactions and other unexpected compounds at the click of a button, in real-time or with later data processing. Users have the traditional options of full scans, XIC, SIM and and the Delta Spectrum, and can acquire XIC-quality data while scanning the entire mass range, allowing the Peak Express software to indicate the m/z directly. The ΔS compares the ion intensity at each m/z interval across the mass spectrum to a base line level measured at the start of the analysis, then records the differential in intensity.
“There is a need for reaction monitoring, compound identification and purification in environments where high levels of contaminants and chemical noise are present,” said David Patteson, Advion CEO. “Our latest addition to the software suite gives users one-click access to detect compounds or provide mass-directed purification without providing the compound mass. Peak Express is like having the expertise of a dedicated mass spectroscopist, digging deep in to the data to find small, unknown peaks that would otherwise have gone undetected, or reveal the detail that would have otherwise been missed. The chemist can “see more” as peaks are revealed and chemical noise is eliminated from the spectrum.”
Peak Express can be used with any technique that generates a peak, e.g. HPLC/CMS, TLC/CMS, Flash/CMS, and FIA, both in real time and for later data processing. The Peak Express software is available now with the expression CMS.