In this interview, Jim Reynolds, an experienced professional in advanced environmental solutions, takes us on a journey through the development and industry adoption of ionized hydrogen peroxide (iHP) technology. He highlights its impact across different sectors and provides insights into the future of this revolutionary disinfection method.
What is ionized hydrogen peroxide, and how is it different from regular hydrogen peroxide?
Ionized hydrogen peroxide (iHP) was developed as a more advanced replacement for vaporized hydrogen peroxide (VHP).
Unlike regular hydrogen peroxide, which might come in high concentrations, like 35 %, it uses a much lower concentration (7.8 %). This low-concentration hydrogen peroxide is activated through a cold plasma arc, generating hydroxyl radicals and •OH ions. These radicals are naturally occurring in the Earth’s lower atmosphere and provide a unique, highly effective method for pathogen elimination without relying solely on chemicals. This makes its use safer for both the environment and infrastructure.
Why was ionized hydrogen peroxide developed?
The development of ionized hydrogen peroxide traces back to the anthrax attacks in 2001. At the time, decontamination methods relied on high-concentration hydrogen peroxide and chlorine dioxide, which were effective but extremely destructive. They caused damage to buildings, peeled paint, and destroyed electronics and equipment.
DARPA, the Defense Advanced Research Projects Agency, initiated research to find a better way to combat such biohazards. This led to the creation of iHP, which uses cold plasma to activate low-concentration hydrogen peroxide, providing a powerful yet non-destructive alternative.
What is cold plasma, and how does it enhance hydrogen peroxide?
Cold plasma is a state of matter used to activate low-concentration hydrogen peroxide. When hydrogen peroxide is passed through a cold plasma arc, it generates highly reactive hydroxyl radicals and •OH ions. These components are the active agents that kill pathogens effectively. Cold plasma is not harmful and produces a targeted activation process that enhances disinfection without destructive side effects.
SteraMist iHP Disinfection - Cold Plasma Science
What are the applications of ionized hydrogen peroxide?
Ionized hydrogen peroxide is very versatile and can be used in a wide range of settings. It is effective for eliminating viruses (e.g., H1N1, Norovirus, COVID), allergens, and pathogens in everyday environments like ambulances, daycare centers, and fire stations. It is also beneficial for homeowners and businesses looking for safe and efficient disinfection solutions.
Aside from being adaptable to different applications, this technology can disinfect spaces without high chemical concentrations, making it ideal for delicate environments. This is why pharmaceutical companies are among its primary users, taking full advantage of its unique features.
How is this technology used in cleanroom and pharmaceutical facilities?
Cleanrooms and pharmaceutical facilities benefit greatly from ionized hydrogen peroxide, especially those that focus on maintaining sterile environments. iHP can be integrated into the building management systems within these facilities, helping to eliminate human error in the cleaning process. This ensures consistent, validated decontamination and allows facilities to maintain strict sterility standards without manual oversight.
This integration is particularly useful for companies that require high precision in maintaining sterile environments.
How does iHP compare to traditional decontamination methods like chlorine dioxide?
Compared to traditional methods such as chlorine dioxide or vaporized hydrogen peroxide, iHP is less destructive and uses lower chemical concentrations. Traditional methods were known for their harshness, often damaging infrastructure during decontamination. In contrast, iHP's cold plasma activation ensures effective pathogen elimination while preserving the integrity of buildings and equipment.
How has the technology been received and adopted by the industry?
The technology is still relatively new, having been declassified in 2009 and registered with the EPA in 2015. However, it has quickly gained traction, particularly in the pharmaceutical industry. Major companies like Pfizer and Merck have adopted it and are integrating it into their facilities and high log efficacy against Geobacillus steraphamillius. Its ability to automate and validate decontamination processes has made it a preferred choice for cleanroom maintenance and pathogen control.
What is the future of ionized hydrogen peroxide technology?
Ionized hydrogen peroxide represents a significant step forward in disinfection technology. Its potential for automation, sustainability, and adaptability makes it a critical tool in combating pathogens in various sectors. As industries continue to prioritize health and safety, the adoption of advanced disinfection methods like iHP is likely to grow, setting new standards in pathogen control and environmental responsibility.
About Jim Reynolds 
Jim Reynolds has a Master’s in Business Administration from Loyola College in Maryland and a Bachelor’s degree in Marketing from King’s College. With this strong academic foundation, he has built a career specializing in advanced environmental solutions.
Since 2014, he has served as a Manufacturer's Sales Representative for TOMI Environmental Solutions, Inc., focusing on ionized hydrogen peroxide (iHP™) technology for decontamination and disinfection. Reynolds has extensive experience in delivering innovative solutions for cleanrooms, pharmaceutical settings, and other environments requiring high standards of sterility and pathogen control.