Evaluation of crystal breakage for pharmaceutical processes

Discover the latest in crystalline product handling with Micromeritics. This webinar will address the challenges of handling crystalline products in the pharmaceutical industry and introduce the newly developed scale-down Agitated Filter Bed Dryer (AFBD)—a state-of-the-art tool designed to assess crystal breakage during drying processes.

Additionally, the webinar will examine critical parameters such as impeller speed, clearance, and solvent content, as well as their impact on the integrity of carbamazepine dihydrate crystals. By analyzing these factors, the innovative AFBD tool aids in optimizing drying conditions, reducing crystal breakage, and enhancing product quality in pharmaceutical manufacturing.

Key topics covered

1. Development of a laboratory scale attrition tester for AFBD based on FT4 chassis.
2. Experimental analysis of attrition of carbamazepine dihydrate due to impeller agitation
3. Solid-state transformations of carbamazepine dihydrate crystals due to thermal and mechanical stressing
4. DVS studies of dehydration and rehydration of carbamazepine dihydrate
5. Impact attrition testing by aerodynamic dispersion using the disperser of G3
6. Simulation of AFBD by Discrete Element Method

Who should attend?

This session is essential for professionals seeking to improve product integrity and manufacturing efficiency.