Three key questions should be considered when selecting a liposome extrusion option. This article answers those questions in relation to Genizer’s range of tools.

Image Credit: Genizer LLC
What pore size is required?
The choice of homogenizer will likely be dictated by the desired pore size. For example, a solo homogenizer can achieve a liposome size of 20–30 nm, but any tool with extrusion capabilities allows for a greater choice of pore size.

Image Credit: Genizer LLC
What types of power are available?
The choice of homogenizer will also depend on the types of power available. For example, jacketed liposome extruders allow gas power to be used, while an electric option is also available if a high-pressure homogenizer with or without an extruder is ideal.
Genizer also offers manual options, including the HandExtruder and HandGenizer.

Image Credit: Genizer LLC
What scale of sample is being processed?
It is also important to consider the scale of the sample or samples being processed. Genizer offers extrusion options from 1 mL to manufacturing scale, with a wide range of size options available.

Image Credit: Genizer LLC
Each Genizer instrument offers specific advantages depending on the application, and the company’s team is available to provide selection advice where required.

Image Credit: Genizer LLC
Acknowledgments
Produced from materials originally authored by Genizer LLC.
About Genizer
Genizer™, located in Technology Link in Greater Los Angeles, is dedicated to advancing homogenizer nanotechnology.
The company provides high-pressure homogenizers, liposome extruders, sanitary heat exchangers, diamond interaction chambers, and high-pressure gauges compatible with other brands of high-pressure homogenizers, pumps, and microfluidizers.
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