Human Leukocyte Antigen News and Research

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Genetic risk for autoimmunity may be linked to differences in gut microbiome

Children with increased genetic risk of type 1 diabetes have different gut microbiomes than those with low risk, a new study found.

20 Aug 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Long-awaited structure offers new insights into rejection of transplanted organs

Rejection of any kind is always hard to deal with, but when one's body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital and Professor of Medicine, shared that between 30% to 40% of kidney transplants are lost over time to rejection.

15 Mar 2019

Researchers identify gene that increases risk of antibiotic reaction

Researchers at Vanderbilt University Medical Center and colleagues have identified a gene that increases the risk for a severe and potentially life-threatening reaction to the commonly prescribed antibiotic vancomycin.

11 Mar 2019

Using TGS technology to make the perfect match even better for stem cell transplant recipients

At Anthony Nolan we save the lives of people with blood cancers and blood disorders that need a stem cell transplant.

4 Mar 2019

Powerful immune molecule silences barrel to protect transplanted organs from rejection

A powerful immune molecule helps protect transplanted organs from rejection by putting a silencer on two other immune molecules that converge to take a direct shot at the organ, scientists report.

5 Feb 2019

Researchers harness immune system to reveal new clues to produce HIV vaccine

The immune system is the body's best defense in fighting diseases like HIV and cancer. Now, an international team of researchers is harnessing the immune system to reveal new clues that may help in efforts to produce an HIV vaccine.

4 Feb 2019

Big data opens door for characterizing immunity-related genome in Japanese population

Although different genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6, in a segment called the major histocompatibility complex (MHC) region.

29 Jan 2019

Acutely injured deceased-donor kidneys are suitable for transplant, study suggests

Organ procurement teams are sometimes leery of accepting kidneys from deceased donors with acute kidney injury, fearing they will harm the recipients. However, a national study chaired by a Johns Hopkins kidney specialist suggests these fears may be unfounded.

7 Dec 2018

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Researchers at the University of Maryland School of Medicine's Maryland Psychiatric Center and Institute for Genome Sciences, along with researchers at the University of Maryland School of Pharmacy, have been awarded a collaborative five-year $1.78 million grant to study the brain-to-gut connection in schizophrenia.

5 Dec 2018

Monash researchers provide insight into intricate peptide changes affecting immune system

Human leukocyte antigen molecules are a group of proteins that help the immune system identify foreign invaders such as viruses and bacteria and which impact a wide variety of clinical outcomes including infection and cancer.

8 Nov 2018

New clinical trial initiated on experimental vaccine to stop the spread of glioblastoma

Rush University Medical Center is part of a new clinical trial testing whether an experimental vaccine can help patients' immune systems stop the spread of glioblastoma -- an aggressive form of brain cancer with veryhttps://www.rush.edu/news/press-releases/rush-testing-new-brain-cancer-vaccine few current treatment options.

14 Sep 2018

New study provides important clues to developing more effective Ebola vaccines

Scientists conducting the first comprehensive study of key immune system cells-;collected from West African Ebola survivors that kill Ebola infected cells have made a surprising discovery that provides important clues to developing effective vaccines against the infection.

24 Jul 2018

People with exposure to paint or other solvents more likely to develop MS

People who have been exposed to paint, varnish and other solvents and who also carry genes that make them more susceptible to developing multiple sclerosis may be at much greater risk of developing the disease than people who have only the exposure to solvents or the MS genes, according to a study published in the July 3, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Jul 2018

Study provides insights into genetics underlying debilitating pediatric kidney disease

New research provides insights into the genetics underlying a debilitating kidney disease in children. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology, could lead to new diagnostics and, ultimately, treatments.

14 Jun 2018

Human Leukocyte Antigen News and Research

Genetic risk for autoimmunity may be linked to differences in gut microbiome

Genetic variations linked with persistence of immunity after routine childhood vaccination

Long-awaited structure offers new insights into rejection of transplanted organs

Researchers identify gene that increases risk of antibiotic reaction

Using TGS technology to make the perfect match even better for stem cell transplant recipients

Powerful immune molecule silences barrel to protect transplanted organs from rejection

Researchers harness immune system to reveal new clues to produce HIV vaccine

Big data opens door for characterizing immunity-related genome in Japanese population

Acutely injured deceased-donor kidneys are suitable for transplant, study suggests

Maryland researchers receive grant to study the brain-to-gut connection in schizophrenia

Monash researchers provide insight into intricate peptide changes affecting immune system

New clinical trial initiated on experimental vaccine to stop the spread of glioblastoma

New study provides important clues to developing more effective Ebola vaccines

People with exposure to paint or other solvents more likely to develop MS

Study provides insights into genetics underlying debilitating pediatric kidney disease

Doctors cure sickle cell patients using allogeneic stem cells

Interaction between dioxin and HLA gene variant activates events associated with rheumatoid arthritis

Environmental pollutants found to worsen rheumatoid arthritis

Research identifies link between rare gene variants and survival after blood and marrow transplant

Researchers develop improved method for calculating type 1 diabetes risk

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