Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Experts advise new measures to combat antimicrobial resistance

An expert panel was formed in the United States to advise the government on how to deal with the problem of antimicrobial resistance (AMR), a growing menace. This panel has now come up with a set of recommendations that could help reduce AMR in humans and animals. Recommendations include development of new vaccines against infections, development of better diagnostic tools to detect the infections early and also new therapies to handle the infections.

22 Sep 2017

Antidepressants used for chronic pain relief come with significant side effects

Chronic pain negatively impacts a person's quality of life. Often, over the counter pain medication, such as ibuprofen or aspirin, are ineffective in alleviating chronic pain. In these instances, a surprising choice is often a drug used to treat an entirely different condition - depression.

5 Sep 2017

Long-term use of anti-inflammatory drugs can slow muscle growth in young people

The long-term use of over-the-counter (OTC) anti-inflammatory drugs can inhibit muscle growth in young, healthy individuals engaging in weight training, according to a new study from Karolinska Institutet, reporting on the effects of ibuprofen on the skeletal muscles and published in Acta Physiologica.

28 Aug 2017

NSAIDs may not be safe for arthritis patients with cardiovascular risk, study shows

Ibuprofen is associated with increased blood pressure and hypertension compared to celecoxib in patients with osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease, according to late-breaking results from the PRECISION-ABPM study presented today in a Hot Line Session at ESC Congress and published in EHJ.

28 Aug 2017

Postoperative patients use fewer opioid medications than prescribed after hernia surgery

A study by investigators from Massachusetts General Hospital and Newton-Wellesley Hospital found that patients prescribed opioid medications after inguinal (groin) hernia surgery used significantly fewer tablets than prescribed, even though they had received fewer than typically administered for such surgery.

9 Aug 2017

When high deductibles hurt: Even insured patients postpone care

In November 2015, Tina Heck was in her garage lifting 40-pound bags of wood pellets to fuel her heating stove, when something went very wrong with her back.

28 Jul 2017

Researchers find new way to protect stem cells from inflammation during wound repair

Scientists have found a new way to protect stem cells from harsh inflammation during wound repair. In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.

20 Jul 2017

Acetaminophen may be effective treatment option for acute mountain sickness

Trekking and mountain climbing are quickly growing in popularity, but.one of the challenges that climbers face is acute mountain sickness (AMS). Previous studies have shown that ibuprofen is an effective way to reduce the risk of AMS.

19 Jun 2017

NSAIDs linked to longer survival for certain colorectal cancer patients

Among long-term colorectal cancer survivors, use of nonsteroidal anti-inflammatory drugs, or NSAIDs, is associated with about a 25 percent reduction in all-cause mortality, according to new research from Fred Hutchinson Cancer Research Center published online in the Journal of Clinical Oncology.

16 Jun 2017

Fever during pregnancy linked to autism risk

According to a new study children born to mothers who have had any kind of fever during pregnancy are at a slightly higher risk of developing and autism spectrum disorder (ASD).

14 Jun 2017

Cesarean patients prescribed more opioid pain medications than needed, study shows

Most women who undergo a cesarean childbirth are prescribed more opioid (narcotic) pain medications than needed upon release from the hospital, a Vanderbilt University Medical Center study shows.

9 Jun 2017

Opioid use gradually increases few years after bariatric surgery, study shows

While the proportion of adults with severe obesity using prescription opioids initially declines in the months after bariatric surgery, it increases within a matter of years, eventually surpassing pre-surgery rates of patients using the potentially addictive pain medications, according to new research from a National Institutes of Health -funded multicenter study led by the University of Pittsburgh Graduate School of Public Health.

6 Jun 2017

Older people with persistent pain more likely to develop dementia

Researchers at UC San Francisco have found that older people with persistent pain show quicker declines in memory as they age and are more likely to have dementia years later, an indication that chronic pain could somehow be related to changes in the brain that contribute to dementia.

5 Jun 2017

Summer perils and ways to avoid, treat them

Summer can bite. It can burn or itch. It can make you extremely sick…or worse.

27 May 2017

New electrochemical method can remove extremely low levels of pollutants from water

When it comes to removing very dilute concentrations of pollutants from water, existing separation methods tend to be energy- and chemical-intensive. Now, a new method developed at MIT could provide a selective alternative for removing even extremely low levels of unwanted compounds.

10 May 2017

Regular use of common painkillers increases risk of heart attack, study reports

A study published in the British Medical Journal suggests that when people use commonly prescribed non-steroidal anti-inflammatory drugs (NSAIDs) for treating pain and inflammation, the risk of heart attack increases as early as in the first week of consumption and particularly within the first month of using such medication in high doses.

10 May 2017

Aspirin used in “baby” doses may prevent breast cancer, study suggests

A new study led by City of Hope researchers has found that regular use of low-dose aspirin (81mg) reduces breast cancer risk in women. Led by Leslie Bernstein, the team found that women who took the low-dose aspirin, also known as “baby” aspirin, at least three times per week had an overall 16% reduced risk of developing breast cancer.

2 May 2017

New chiral molecular sieves may lead to production of better drugs

An international team of researchers, led by Mark E. Davis at Caltech, has succeeded in making the first chiral molecular sieves. This discovery opens new areas of investigation in both chemistry and biology, and has broad implications for pharmaceutical companies and other specialized chemical manufacturers.

2 May 2017

Scientists find way to provide longer-lasting pain relief using MOFs

To treat headaches, back pain or fever, most of us have reached for ibuprofen at one point or another. But we often have to take doses every four to six hours if the pain warrants it.

26 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017