Iron Deficiency News and Research

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A deficiency of iron can result from a number of different causes. Inadequate iron in the diet, impaired absorption of iron, and excessive bleeding are all examples of conditions that can lead to iron deficiency.

Delayed umbilical cord clamping is effective even when newborn is placed on mother's abdomen

A recent study has shown that a newborn benefits from delayed cord clamping even when placed immediately on the mother's abdomen.

17 Apr 2014

Baxter reports topline results from BAX 111 Phase 3 trial for treatment of von Willebrand disease

Baxter International Inc. today announced topline results from a Phase 3 clinical trial evaluating the safety, efficacy and pharmacokinetics (PK) of BAX 111. BAX 111 is a recombinant von Willebrand factor (rVWF) under investigation for the treatment of bleeding episodes in patients with von Willebrand disease, the most common type of inherited bleeding disorder.

From Baxter International Inc. 16 Apr 2014

People with low and very high levels of transferrin saturation ratio are at increased risk of death

A new study led by researchers at the Graduate Entry Medical School, University of Limerick has found that people with low levels and very high levels of a commonly measured laboratory test, the “transferrin saturation ratio” are at an increased risk of death. The test is a measure of the amount of available iron in the bloodstream with low levels generally reflecting a state of iron deficiency and high levels suggesting a relative excess.

1 Apr 2014

Iron deficiency predicts lower IQ scores in children adopted from institutional settings

Iron deficiency predicts lower IQ scores and poor higher-order thinking skills in children adopted from institutional settings like orphanages, according to a new longitudinal study.

6 Mar 2014

Proper good night's sleep promotes both mental and physical health

Getting a good night's sleep means more than you probably think. "I would say the importance of sleep is definitely underestimated by the general public," said Dr. Sandhya Kumar, assistant professor of neurology at Wake Forest Baptist Medical Center and medical director of its Sleep Center.

23 Jan 2014

Shield Therapeutics reports positive top-line data from pivotal Phase 3 programme of ST10

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces strongly positive top-line data from the pivotal Phase 3 programme of ST10 for the treatment of iron deficiency anaemia in inflammatory bowel disease.

7 Jan 2014

FDA accepts Shield Therapeutics' IND application to begin ST10 Phase 3 pivotal study for IDA treatment

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that the US Food and Drug Administration has accepted its Investigational New Drug application to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease. The Company plans to initiate the Phase 3 study in the US in H1 2014 and positive data would be the cornerstone of a subsequent NDA submission.

16 Dec 2013

NOXXON Pharma reports interim data from two phase IIa studies of anti-CXCL12/SDF-1 Spiegelmer NOX-A12

NOXXON Pharma disclosed interim data from two independent clinical phase IIa studies of the anti-CXCL12/SDF-1 Spiegelmer olaptesed pegol (NOX-A12) at the 55th annual meeting of the American Society of Hematology in New Orleans, LA, USA from 7-10 December 2013.

9 Dec 2013

New report on global prevalence of anemia

Despite increasing efforts to diagnose and treat anemia worldwide, there remains a surprisingly large global burden of the disease, particularly among young children and women, according to a new report on trends in anemia between 1990 and 2010.

3 Dec 2013

U-M study explores exercise-induced iron-deficiency anemia in female runners

When Kaitlyn Patterson's fatigue progressed to hyperventilating even during slow runs, and then forced her to quit high school distance running for the season, she knew something was very wrong. Patterson had exercise-induced iron-deficiency anemia, a common, perplexing problem among elite female athletes, especially endurance runners. Later, as a University of Michigan sophomore, she was so interested in the topic that she applied for an undergraduate research position in the lab of Peter Bodary, U-M clinical assistant professor of movement science and health & fitness.

22 Nov 2013

New paper highlights correlations between changes in natural systems and potential health outcomes

A new paper from members of the HEAL (Health & Ecosystems: Analysis of Linkages) consortium delineates a new branch of environmental health that focuses on the public health risks of human-caused changes to Earth's natural systems.

20 Nov 2013

Shield Therapeutics files IND application with FDA to initiate ST10 Phase 3 study

Shield Therapeutics, an independent specialty pharmaceutical company focused on the development of mineral-derived hospital pharmaceuticals, today announces that it has filed an investigational new drug application with the US Food and Drug Administration to initiate a Phase 3 pivotal study of ST10, its novel oral iron-replacement therapy, for the treatment of iron deficiency anaemia in pre-dialysis patients with chronic kidney disease.

12 Nov 2013

Triferic drug is effective in preventing iron deficiency in patients with chronic kidney disease

Doctors at the North Shore-LIJ Health System on Saturday will present late-breaking data showing that an investigational drug Triferic is well tolerated and effective in treating iron deficiency in patients with chronic kidney disease undergoing dialysis.

11 Nov 2013

WHO: Iron deficiency causes loss of 48,225 disability-adjusted life-years worldwide

Data supporting the need for better recognition of iron deficiency will be presented this week at the United European Gastroenterology Week Congress in Berlin. Iron deficiency is frequently under-diagnosed, resulting in increased hospitalisation, reduced quality of life and higher death rates in patients with comorbid conditions. The WHO has estimated that iron deficiency causes the loss of 48,225 disability-adjusted life-years worldwide, more than is seen with lung cancer.

12 Oct 2013

HOOKVAC consortium awarded grant to develop, test vaccine for human hookworm

The HOOKVAC consortium, led by the Academic Medical Center at the University of Amsterdam, today announced it has been awarded a grant of six million Euros from the European Commission FP7 programme to expand the Sabin Vaccine Institute Product Development Partnership’s (Sabin PDP) work to develop and test a vaccine for human hookworm, a disease that infects 600-700 million of the world’s poorest people.

27 Sep 2013

HOOKVAC consortium to begin first clinical testing of human hookworm vaccine in West Africa

The HOOKVAC consortium, led by the Academic Medical Center (AMC) at the University of Amsterdam, today announced it has been awarded a grant of six million Euros from the European Commission FP7 programme to expand the Sabin Vaccine Institute Product Development Partnership's (Sabin PDP) work to develop and test a vaccine for human hookworm, a disease that infects 600-700 million of the world's poorest people.

27 Sep 2013

Phobias, anxiety are typical reasons why many decline to donate blood

As few as 3 percent of Americans eligible to donate blood do, and fear and anxiety are common reasons why many decline to give. U.S. hospitals are always in need of new donors; at Mayo Clinic, that need is heightened by concern about iron deficiency in frequent givers.

11 Sep 2013

Iron deficiency anemia may offer protection against malaria infection

Children in a malaria-endemic community in Ghana who received a micronutrient powder with iron did not have an increased incidence of malaria, according to a study in the September 4 issue of JAMA. Previous research has suggested that iron supplementation for children with iron deficiency in malaria-endemic areas may increase the risk of malaria.

4 Sep 2013

Celiac disease patients with persistent intestine damage are at higher risk of lymphoma

Patients with celiac disease who had persistent intestine damage (identified with repeat biopsy) had a higher risk of lymphoma than patients whose intestines healed, according to findings published in the August 6, 2013, issue of Annals of Internal Medicine.

6 Aug 2013

Research: Vegetarian athletes can stay competitive with balanced plant-base diets

A balanced plant-based diet provides the same quality of fuel for athletes as a meat-based diet, provided vegetarians seek out other sources of certain nutrients that are more commonly found in animal products, according to a presentation at the 2013 Institute of Food Technologists Annual Meeting & Expo.

18 Jul 2013