Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 7, one copy inherited from each parent, form one of the pairs. Chromosome 7 spans about 159 million DNA building blocks (base pairs) and represents more than 5 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 7 likely contains about 1,150 genes.
Genes on chromosome 7 are among the estimated 20,000 to 25,000 total genes in the human genome.
Giving girls with Turner syndrome low doses of estrogen, as well as growth hormone, years before the onset of puberty, increases their height and offers a wealth of other benefits, say a team of researchers led by Thomas Jefferson University.
Heart transplant recipients and their physicians are likely more concerned with the function of the donated organ than with the donor's DNA sequences that tag along in the new, healthy tissue.
Johns Hopkins scientists, reporting in the journal Molecular Psychiatry, have identified a small region on chromosome 2 that is associated with increased risk for attempted suicide. This small region contains four genes, including the ACP1 gene, and the researchers found more than normal levels of the ACP1 protein in the brains of people who had committed suicide. This protein is thought to influence the same biological pathway as lithium, a medication known to reduce the rate of suicidal behavior.
Clinical studies of Resveratrol--recognized for its proven role in activating the longevity gene to inhibit age-related diseases--have shown that its antioxidant power provides resistance before and after exposure to hazardous radiation.
Looking at the dark stripes on the tiny zebrafish you might not expect that they hold a potentially important clue for discovering a treatment for the deadly skin disease melanoma. Yet melanocytes, the same cells that are are responsible for the pigmentation of zebrafish stripes and for human skin color, are also where melanoma originates.
A new UK study will provide better diagnoses for children with developmental disorders caused by changes in their genetic makeup. Scientists and clinicians will build a new national resource of genetic information and symptoms, based on data from 12,000 children who have a serious delay in their physical or mental development or are born with multiple malformations.
"Exceptional, Unconventional Research Enabling Knowledge Acceleration" - is the name of a rare and competitive grant that Reenan recently won from the National Institutes of Health. Beginning April 1, Reenan will use the four-year, $1.3-million award to look for genes that can suppress seizures in fruit flies that he has cleverly engineered to mimic human epilepsy.
Scientists at the European Molecular Biology Laboratory in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT.
Primary care doctors are less likely to refer short girls than short boys for diagnostic testing that can reveal underlying medical reasons for their short stature, according to a new study of an urban pediatric population in Philadelphia. Girls with medical conditions causing their short stature may go undiagnosed, or may be diagnosed later than boys, limiting timely treatment.
If a big bunch of your brain cells suddenly went rogue and decided to become fat cells, it could cloud your decision-making capacity a bit. Fortunately, early in an organism's development, cells make firm and more-or-less permanent decisions about whether they will live their lives as, say, skin cells, brain cells or, well, fat cells.
Life Technologies Corporation today announced that it is the first life science tools provider entering clinical trials to prove the safety and effectiveness of their DNA sequence-based typing (SBT) platform for analysis of the Human Leukocyte Antigen (HLA) system. Submission for 510(k) clearance of this SBT platform will follow completion of the clinical trials, which is anticipated this summer.
RainDance Technologies, Inc., today announced the commercial availability of the ASDSeq™ and XSeq™ Research Screening Panels. Developed in collaboration with Emory University and Greenwood Genetic Center, the two comprehensive panels enable researchers to simultaneously interrogate key genes known to be linked to X-chromosome disorders and syndromic forms of Autism Spectrum Disorder (ASD) using next-generation sequencing.
Celera Corporation today reported net revenues of $34.9 million for the fourth quarter of 2010 that ended December 25, 2010, compared to $39.2 million for the prior year quarter.
A world-renowned fragile X syndrome researcher, who was the first to identify the long-sought genetic abnormality responsible for this disorder, will be honored by the March of Dimes.
AbCheck s.r.o., the multi antibody discovery platforms company, announced today the company has licensed a proven antibody yeast display technology from CELEXION LLC (Cambridge, MA, USA). The addition of this platform to AbCheck's current phage display platform places the company as the World's only antibody discovery specialist leveraging the advantage of working with both phage and yeast display technologies.
Norwegian researchers have discovered genes that increase not only one's risk of lung cancer, but perhaps one's urge to smoke as well. Now these researchers are working on developing a blood test for lung cancer.
Despite dramatically improved survival rates for childhood acute lymphoblastic leukemia, relapse remains a leading cause of death from the disease. Work led by St. Jude Children's Research Hospital investigators identified mutations in a gene named CREBBP that may help the cancer resist steroid treatment and fuel ALL's return.
Burkitt's lymphoma is one of the most aggressive tumors affecting humans. Multiple alterations in genes that regulate cell proliferation rate explain its aggressive behavior.
European researchers have devised a blood test that could help pregnant women avoid the invasive procedures now used to diagnose Down syndrome prenatally and make the diagnosis with 100% accuracy. The study report was published this Sunday in Nature Medicine.
Gene therapy that boosts the ability of brain cells to gobble up toxic proteins prevents development of Alzheimer's disease in mice that are predestined to develop it, report researchers at Georgetown University Medical Center. They say the treatment - which is given just once - could potentially do the same in people at the beginning stages of the disease.
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