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ITBCC takes revolutionary step in improving biomarker assessment in colorectal cancer

In colorectal cancer, the presence of invasive tumor cells at the advancing edge of the tumor can provide valuable information on prognosis. Initiated by the Colorectal Cancer Research Group at the Institute of Pathology, University of Bern, a consensus conference was held to determine how this phenomenon should best be put into practice.

31 May 2016

Counsyl expands into oncology market to increase cancer risk screening

Counsyl, a DNA testing and genetic counseling service, today announced its expansion into the oncology market, with a focus on advancing cancer risk screening and helping cancer prevention efforts.

31 May 2016

Zinbryta gets FDA approval for treating adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Zinbryta (daclizumab) for the treatment of adults with relapsing forms of multiple sclerosis (MS). Zinbryta is a long-acting injection that is self- administered by the patient monthly.

28 May 2016

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

For uninsured patients who are at a high risk for colorectal cancer (CRC), performing free screening colonoscopies can identify cancer at an earlier stage and appears to be cost neutral from a hospital system perspective, according to study results published online in the Journal of the American College of Surgeons ahead of print publication.

27 May 2016

Early-life stress may lead to functional dyspepsia in adulthood

Traumatic events early in life can increase levels of norepinephrine—the primary hormone responsible for preparing the body to react to stressful situations—in the gut, increasing the risk of developing chronic indigestion and anxiety during adulthood, a new study in American Journal of Physiology—Gastrointestinal and Liver Physiology reports.

27 May 2016

Researchers find new clue to understanding 'chemo brain' in cancer patients

During and after chemotherapy, many cancer patients describe feeling a mental fog, a condition that has been dubbed "chemo brain." Why this happens is unclear, but researchers have found a new clue to understanding this syndrome.

26 May 2016

$ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients$

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

Data from the 48-week ART trial, presented today at the Digestive Disease Week meeting, showed that remission and response rates were 37.2% and 53.2% respectively at week 12, in patients with moderate-to-severe, steroid-dependent active ulcerative colitis (UC) with insufficient response or intolerance to immunosuppressants and / or biologics when treated with between five and eight sessions with Adacolumn.

26 May 2016

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

A group of researchers at Osaka University elucidated how a gene named Ly6/Plaur domain containing 8 (Lypd8) inhibits bacterial invasion of colonic epithelia, regulating intestinal inflammation. This achievement may lead to the development of drugs for ulcerative colitis.

25 May 2016

Nutrition, safety tips for grilling season

Cooking meat, including beef, pork, fish, or poultry, with high-temperature methods such as pan frying or grilling directly over an open flame can increase exposure to chemicals that can cause changes in DNA that may increase the risk of cancer, according to the National Cancer Institute.

25 May 2016

UofL expands oncology research with addition of 33,000 human tissue samples

The University of Louisville has expanded its oncology research strength through the addition of approximately 33,000 human tissue samples and specimens. The samples were transferred by Catholic Health Initiatives to further the shared commitment and collaboration in advancing research and action in the fight against cancer.

25 May 2016

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list."

24 May 2016

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

The lab of Rice University synthetic organic chemist K.C. Nicolaou has reported the streamlined total synthesis of delta12-prostaglandin J3, a molecule previously claimed to kill leukemic cancer cells.

24 May 2016

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Patients with ulcerative colitis (UC) may improve their symptoms with a transplantation of healthy stool from donors, according to Australian researchers. The findings were presented by Dr Sudarchan Paramsothy MD, a gastroenterologist from the University of New South Wales, Australia at the Digestive Disease Week conference in San Diego, California between the 21st to 24th May.

24 May 2016

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

A team of researchers from Cornell University in Ithaca, New York demonstrated a drug delivery mechanism that utilizes two independent vehicles, allowing for delivery of chemically and physically dis-tinct agents.

23 May 2016

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today.

23 May 2016

Ramizol drug shows promise in treatment of Clostridium difficile infections

A scientific paper released today in the Journal of Antibiotics presents the pre-clinical development of Ramizol, a first generation drug belonging to a new class of styrylbenzene antibiotics with a novel mechanism of action.

19 May 2016

Tecentriq drug gets FDA approval to treat urothelial carcinoma

The U.S. Food and Drug Administration today approved Tecentriq (atezolizumab) to treat the most common type of bladder cancer, called urothelial carcinoma. This is the first product in its class (PD-1/PD-L1 inhibitors) approved to treat this type of cancer.

19 May 2016

Maintaining balance of P1 and P2 isoforms vital for reducing colon cancer, colitis risk

Inflammatory bowel disease (IBD), of which Crohn's disease and ulcerative colitis are the main types, is on the increase in the United States, affecting more than 1.6 million people and explaining perhaps the increase in advertisements offering treatments and cures.

18 May 2016

Rural hospitals may work well for straightforward surgeries in relatively healthy patients

They may be in small towns. They may only have a couple of surgeons. But for common operations, they may be safer and less expensive than their larger cousins, a new study finds.

18 May 2016

Research on immune system sets stage for novel approach to cancer immunotherapy

Basic research into the dual nature of certain immune system cells has set the stage for a new approach to cancer immunotherapy that avoids some of the shortcomings associated with other methods, scientists at Dana-Farber Cancer Institute report in a new study in the Proceedings of the National Academy of Sciences.

17 May 2016

Colon News and Research

ITBCC takes revolutionary step in improving biomarker assessment in colorectal cancer

Counsyl expands into oncology market to increase cancer risk screening

Zinbryta gets FDA approval for treating adults with relapsing forms of MS

Free screening colonoscopies for uninsured, high-risk CRC patients may help in early detection of cancer

Early-life stress may lead to functional dyspepsia in adulthood

Researchers find new clue to understanding 'chemo brain' in cancer patients

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

Researchers discover how specific gene inhibits bacterial invasion of colonic epithelia

Nutrition, safety tips for grilling season

UofL expands oncology research with addition of 33,000 human tissue samples

Purdue researchers find potential way to overcome limitations posed by CAR T-cell therapy

Rice University researchers set stage for large-scale synthesis of cytotoxic agent to treat cancer

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Cornell researchers develop nanoparticle-based drug delivery mechanism for combination cancer therapy

Diet experiments on Lynch syndrome mouse model may help in early detection of colon cancer

Ramizol drug shows promise in treatment of Clostridium difficile infections

Tecentriq drug gets FDA approval to treat urothelial carcinoma

Maintaining balance of P1 and P2 isoforms vital for reducing colon cancer, colitis risk

Rural hospitals may work well for straightforward surgeries in relatively healthy patients

Research on immune system sets stage for novel approach to cancer immunotherapy

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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