Immune System News and Research

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All patients with rheumatic disorders recommended to receive pneumococcal vaccine

Patients with rheumatoid arthritis, lupus, and other rheumatic conditions are more at risk for complications and death from pneumonia, meningitis, and other bacterial infections, yet most have not been vaccinated against infection.

29 Dec 2022

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

A clinical trial led by the National Cancer Institute (NCI), part of the National Institutes of Health, has resulted in the first approval of a treatment for advanced alveolar soft part sarcoma (ASPS).

28 Dec 2022

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

Study reveals why some germinal centers persist for months rather than weeks

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities.

23 Dec 2022

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

High levels of ammonia in tumors lead to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed.

23 Dec 2022

Using the gut microbiome to understand and treat respiratory diseases

Researchers review the role of the gut microbiome in certain respiratory diseases.

22 Dec 2022

Research serves as a platform to identify therapeutic drugs for schizophrenia

Inflammation and overactivation of the immune system in the brain can cause loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases.

22 Dec 2022

Extracellular vesicles enhance cancer immunotherapy

Nano-sized membrane bubbles known as extracellular vesicles activate the immune system in mice and seem to render their tumors sensitive to a type of immunotherapy drug called a checkpoint inhibitor.

22 Dec 2022

‘Caged … for no fault of your own’: Detainees dread covid while awaiting immigration hearings

In October, Yibran Ramirez-Cecena didn't alert the staff at Stewart Detention Center to his cough and runny nose.

22 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

UMass Amherst microbiologist receives NIH grant to develop more effective treatments for tuberculosis

A microbiologist at the University of Massachusetts Amherst has received a National Institutes of Health grant to support research aimed ultimately at developing new, more effective treatments for tuberculosis (TB).

21 Dec 2022

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

Study reveals why human lymph nodes lose their function with age

A new study from researchers at Uppsala University presents novel findings on why human lymph nodes lose their function with age and the consequences for the effectiveness of our immune system. The article has been published in The Journal of Pathology.

21 Dec 2022

Immune System News and Research

All patients with rheumatic disorders recommended to receive pneumococcal vaccine

NCI-led clinical trial results in the first approval of a treatment for advanced alveolar soft part sarcoma

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

Study reveals why some germinal centers persist for months rather than weeks

High ammonia levels lead to fewer T cells and immunotherapy resistance in colorectal cancer

Using the gut microbiome to understand and treat respiratory diseases

Research serves as a platform to identify therapeutic drugs for schizophrenia

Extracellular vesicles enhance cancer immunotherapy

‘Caged … for no fault of your own’: Detainees dread covid while awaiting immigration hearings

New methods can advance the development of rapid diagnostics for many infectious diseases

UMass Amherst microbiologist receives NIH grant to develop more effective treatments for tuberculosis

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Study reveals why human lymph nodes lose their function with age

CARxALL clinical trial approved to evaluate CAR-T technology for patients with T-cell leukemia subtype

New method uses artificial DNA to target and kill cancer cells

Huge multi-omic data analysis deciphers colorectal cancer genetics

Researchers devise new biomarker-based strategy to screen for myocarditis caused by cancer treatment

COVID-19 epidemiology can be estimated using blood donation samples

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Immunology eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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