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Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to radiation treatment, and the factors that predict patient outcomes are unclear. Moffitt Cancer Center researchers report that liver metastases have different sensitivities to radiation therapy based on the location of the primary tumor.

13 Apr 2016

Umea University researchers find link between levels of DNA building blocks and colon cancer

When cells divide, the proper balance between the four DNA building blocks is required in order for the DNA to be copied without the introduction of potentially harmful mutations. Researchers at Umea University in Sweden have now shown a connection between levels of DNA building blocks - dNTPs - and colon cancer. This discovery has been published in the Proceedings of the National Academy of Sciences.

13 Apr 2016

Surgeon to perform live-streamed Virtual Reality surgery on colon cancer patient using Mativision technology

An operation on a patient with colon cancer at The Royal London Hospital will be the first in the world to be broadcast live through pioneering virtual reality (VR) technology.

13 Apr 2016

Researchers link higher levels of vitamin D to reduced cancer risk

Researchers at University of California, San Diego School of Medicine report that higher levels of vitamin D - specifically serum 25-hydroxyvitamin D - are associated with a correspondingly reduced risk of cancer. The findings are published in the April 6, online issue of PLOS ONE.

7 Apr 2016

New CWRU study identifies three glycosyltransferases as major mutational targets in colorectal cancer

Little is known about the molecular basis of aberrant protein glycosylation, a complex enzymatic process that is a hallmark of many human cancers including colorectal cancers (CRC), and how it may contribute to tumor progression. In a new study published in Scientific Reports, an online journal of the Nature Publishing Group, scientists at Case Western Reserve University School of Medicine have successfully characterized the mutational landscapes of glycosylation-associated genes in colon cancer, identifying three glycosyltransferases as significant mutational targets in CRC.

4 Apr 2016

USC study finds coffee consumption decreases colorectal cancer risk

Whether you like your coffee black, decaf, half-caff or even instant, feel free to drink up. Researchers at the University of Southern California (USC) Norris Comprehensive Cancer Center of Keck Medicine of USC have found that coffee consumption decreases the risk of colorectal cancer.

2 Apr 2016

U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer.

2 Apr 2016

Study finds that married men over age 55 more likely to get colonoscopy

A national study involving 804 couples found that married men over age 55 were almost 20 percent more likely to have had a screening colonoscopy in the previous five years than men who were not married. Men married to women who are happier with the marital relationship were nearly 30 percent more likely. That rises to more than 40 percent if their wives were highly educated.

2 Apr 2016

Changing one atom in InsP6 inhibitor can increase its ability to neutralize toxins in the gut

Infections with bacterium Clostridium difficile have rapidly become a significant medical problem in hospitals and long-term care facilities. The bacteria cause diarrhea and life-threatening inflammation of the colon by producing toxins that kill the endothelial cells that form the lining of the gut.

26 Mar 2016

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Advances in personalized medicine allow doctors to select the most promising drugs for certain types of malignant tumors.

24 Mar 2016

Blocking Mena protein could help prevent cancer metastasis, says MIT researcher

A new study from MIT reveals how cancer cells take some of their first steps away from their original tumor sites. This spread, known as metastasis, is responsible for 90 percent of cancer deaths.

16 Mar 2016

Prognostic test could help lower cancer recurrence for colorectal patients

Colorectal cancer, one of the most commonly diagnosed cancers in the United States, is not a commonly discussed disease. Often symptomless in early stages, the cancer is more difficult to treat as it progresses, requiring chemotherapy in later stages. Researchers at the University of Notre Dame are working on a way to identify patients who would benefit from chemotherapy before the cancer progresses.

15 Mar 2016

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Researchers on Mayo Clinic's Florida campus have shut down one of the most common and lethal forms of lung cancer by combining the rheumatoid arthritis drug auranofin with an experimental targeted agent.

15 Mar 2016

Research finds new molecular details of facultative stem cells

In a study published this week in PLOS Genetics, scientists Nareg J. Djabrayan and Jordi Casanova from the Institute for Research in Biomedicine and CSIC, have identified two molecular signals and the pathway of events that allows cells in a tissue that are already specialized to regain their behaviour as stem cells.

14 Mar 2016

Researchers uncover antitumoral nature of maslinic acid in colon cancer cells

Researchers from the University of Granada, in collaboration with the universities of Barcelona and Jaen, have brought to light the antitumoral nature of maslinic acid (a compound derived from olives) in Caco-2 p53-deficient colon adenocarcinoma cells in the short term.

11 Mar 2016

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

UNC Lineberger Comprehensive Cancer Center researchers have discovered that a deficiency in a key protein that regulates immune system warning signals could be a new biomarker for colorectal cancer, the second largest cancer killer in the United States. They believe the marker could be used to gauge response to a potential new treatment for the disease.

11 Mar 2016

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).

10 Mar 2016

Valley Hospital, Holy Name Medical Center collaborate to defeat C. difficile

The Valley Hospital in Ridgewood, NJ, and Holy Name Medical Center in Teaneck, NJ, are collaborating to defeat a common foe: a dangerous drug-resistant bacterium called Clostridium difficile, or C. difficile.

9 Mar 2016

Dietary broccoli may protect against liver cancer

Consumption of broccoli has increased in the United States over the last few decades as scientists have reported that eating the vegetable three to five times per week can lower the risk of many types of cancer including breast, prostate, and colon cancers.

4 Mar 2016

High-fat diet may make intestinal stem cells to become cancerous

Over the past decade, studies have found that obesity and eating a high-fat, high-calorie diet are significant risk factors for many types of cancer. Now, a new study from Whitehead Institute and MIT's Koch Institute for Integrative Cancer Research reveals how a high-fat diet makes the cells of the intestinal lining more likely to become cancerous.

3 Mar 2016

Colon News and Research

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Umea University researchers find link between levels of DNA building blocks and colon cancer

Surgeon to perform live-streamed Virtual Reality surgery on colon cancer patient using Mativision technology

Researchers link higher levels of vitamin D to reduced cancer risk

New CWRU study identifies three glycosyltransferases as major mutational targets in colorectal cancer

USC study finds coffee consumption decreases colorectal cancer risk

U of S-led researchers develop novel class of compounds for effective cancer treatment

Study finds that married men over age 55 more likely to get colonoscopy

Changing one atom in InsP6 inhibitor can increase its ability to neutralize toxins in the gut

Researchers develop metastasis-on-a-chip system to advance cancer investigation, drug discovery

Blocking Mena protein could help prevent cancer metastasis, says MIT researcher

Prognostic test could help lower cancer recurrence for colorectal patients

Combination drug therapy may stop KRAS-mediated lung adenocarcinoma

Research finds new molecular details of facultative stem cells

Researchers uncover antitumoral nature of maslinic acid in colon cancer cells

NLRX1 protein could be new biomarker for colorectal cancer, find UNC Lineberger researchers

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

Valley Hospital, Holy Name Medical Center collaborate to defeat C. difficile

Dietary broccoli may protect against liver cancer

High-fat diet may make intestinal stem cells to become cancerous

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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