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Methotrexate reduces joint damage in hand osteoarthritis

A new study presented at the 2019 ACR/ARP meeting shows that methotrexate stopped further damage to the hand joints and even perhaps improved bone remodeling in patients with osteoarthritis (OA) of the hand, when they were assessed at 3 and 12 months.

11 Nov 2019

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis.

11 Nov 2019

Opioids do not improve quality of life or depression in OA patients

New research presented at the 2019 ACR/ARP Annual Meeting suggests that opioids contribute no measurable benefit to quality of life or depression for patients with osteoarthritis (OA).

11 Nov 2019

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

According to new research findings presented at the 2019 ACR/ARP Annual Meeting, methotrexate did not demonstrate superior efficacy over placebo for pain relief and function evolution at three and 12 months in patients with erosive hand osteoarthritis.

11 Nov 2019

Dengue vaccine from Takeda shows promise

Officials have confirmed the initial success with trials of Dengue vaccine. Dengue, a viral disease borne by mosquitoes is considered to be one of the top ten health threats says the world Health Organization (WHO). Since the beginning of the outbreaks and the hundreds of deaths due to this infection, researchers have been on the lookout for vaccines to prevent this infection.

10 Nov 2019

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Diabetic kidney disease remains one of the most intractable complications of diabetes. Progress has been made using glycemic and blood pressure control, but the search continues for improved treatments for the estimated one in four adults with diabetes who has some level of nephropathy and continues at risk for eventual kidney failure.

10 Nov 2019

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Supplements of vitamin D and omega-3 fatty acids (often sold as fish oil) do not help people with type 2 diabetes stave off chronic kidney disease, according to findings from the largest clinical study to date of the supplements in this patient population.

10 Nov 2019

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

According to new research findings presented this week at the 2019 ACR/ARP Annual Meeting, the live zoster virus vaccine is safe for people who are currently receiving tumor necrosis factor inhibitor (TNFi) biologic therapies for various indications.

10 Nov 2019

Big data provide opportunity for research, drive learning at the healthcare system level

ISPOR, the professional society for health economics and outcomes research-;held its third plenary session at ISPOR Europe 2019, "Big Data Healthcare: Endless Opportunities for Research and Learning," this morning in Copenhagen, Denmark.

7 Nov 2019

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Vitamin D and marine omega-3 fatty acids -- also known as fish oil -- are purported to have many health benefits, including reducing systemic inflammation.

7 Nov 2019

Advice to pull a drug used to prevent premature birth sparks controversy

It has been recommended that a drug currently used to prevent preterm birth should be removed from the market.

6 Nov 2019

Implanted nerve stimulation devices provide sustained pain relief in 60 days

Patients who have chosen to treat chronic pain with implanted peripheral nerve stimulation no longer need to be tethered permanently to the device.

6 Nov 2019

Single vaping episode of cannabis could yield positive results in urine drug tests

In a study of six adults, Johns Hopkins Medicine researchers report evidence that a single vaping episode of cannabis that is similar in chemical composition to that found in legal hemp products could possibly result in positive results on urine drug screening tests commonly used by many employers and criminal justice or school systems.

From Johns Hopkins Medicine 4 Nov 2019

Three-drug combination improves lung function, reduces symptoms in CF patients

A phase three clinical trial that UT Southwestern participated in determined that a three-drug combination improved lung function and reduced symptoms in cystic fibrosis patients who have a single copy of the most common genetic mutation for the disease.

31 Oct 2019

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

November is National Pancreatic Cancer Awareness month. This year alone, more than 56,000 Americans will be diagnosed with pancreatic cancer. Pancreatic tumors are particularly aggressive and hard to treat "due to a mutational profile that makes it resistant to therapies that work better for other tumor types," explains Angela Alistar, MD, medical director of GI Oncology at Morristown Medical Center.

30 Oct 2019

New TB vaccine: mid-phase trials confirm safety, long-term prevention

A new study published on October 29, 2019, in the New England Journal of Medicine, reports a new vaccine which could change the face of tuberculosis prevention. The disease kills 1.5 million people worldwide each year.

30 Oct 2019

IU researcher receives NIH grant to perform clinical trial on cirrhosis

An Indiana University School of Medicine researcher has been awarded a five-year, $1.8 million grant from the National Institutes of Health for a clinical trial, aimed at providing new avenues to improve liver function for patients with alcoholic cirrhosis.

30 Oct 2019

Homeopathy quackery - NHS leaders urge caution

A new controversy is ripe, what with the head of the UK National Health Service (NHS), Simon Stevens, publicly expressing his “serious concerns” about the “fundamentally flawed” practice of homeopathy.

29 Oct 2019

Anti-inflammatory agents can safely, effectively reduce symptoms of major depression

Anti-inflammatory agents, such as aspirin/paracetamol, statins, and antibiotics, can safely and effectively curb the symptoms of major depression, finds a pooled analysis of the available evidence, published online in the Journal of Neurology Neurosurgery & Psychiatry.

29 Oct 2019

Mindfulness meditation can boost positive long-term effects of psilocybin

Recent years have seen a renewed interest in the clinical application of classic psychedelics in the treatment of depression and anxiety disorders.

24 Oct 2019

Placebo News and Research

Methotrexate reduces joint damage in hand osteoarthritis

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Opioids do not improve quality of life or depression in OA patients

Methotrexate appears to facilitate bone remodeling in patients with osteoarthritis

Dengue vaccine from Takeda shows promise

PERL study: Reducing uric acid levels does not benefit type 1 diabetes patients with kidney disease

Vitamin D, fish oil supplements do not help preserve kidney health in people with type 2 diabetes

Study reveals safety, efficacy of live zoster vaccine for people taking TNF inhibitors

Big data provide opportunity for research, drive learning at the healthcare system level

Vitamin D and omega-3 fatty acids are not effective at reducing systemic inflammation

Advice to pull a drug used to prevent premature birth sparks controversy

Implanted nerve stimulation devices provide sustained pain relief in 60 days

Single vaping episode of cannabis could yield positive results in urine drug tests

Three-drug combination improves lung function, reduces symptoms in CF patients

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

New TB vaccine: mid-phase trials confirm safety, long-term prevention

IU researcher receives NIH grant to perform clinical trial on cirrhosis

Homeopathy quackery - NHS leaders urge caution

Anti-inflammatory agents can safely, effectively reduce symptoms of major depression

Mindfulness meditation can boost positive long-term effects of psilocybin

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