Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Cone snail venom produces new type of insulin

Diabetes is a global health issue affecting millions. In 2014, there were 422 million diabetics, compared to 108 million in 1989. The condition can be treated with diet, physical activity, medicines like synthetic insulin injections, and regular screening.

3 Jun 2020

Breakthrough discovery could lead to treatment of Fragile X syndrome

Scientists at the Hotchkiss Brain Institute, Alberta Children's Hospital Research Institute, and Owerko Centre at UCalgary's Cumming School of Medicine have made a breakthrough discovery that could lead to treatment of Fragile X syndrome, the leading genetic cause of Autism Spectrum Disorder.

2 Jun 2020

Cone snail insulin research could jumpstart the development of better diabetes treatments

Nearly a century after insulin was discovered, an international team of researchers including University of Utah Health scientists report that they have developed the world's smallest, fully functional version of the hormone, one that combines the potency of human insulin with the fast-acting potential of a venom insulin produced by predatory cone snails.

1 Jun 2020

Out-of-pocket health care costs for patients with type 1 diabetes is $2,500 a year, study reveals

Adults and children with type 1 diabetes will spend an average of $2,500 a year out-of-pocket for health care - but insulin isn't always the biggest expense - new research suggests.

1 Jun 2020

Oral antidiabetics improve outcomes in diabetics with colorectal cancer

Bottom Line: Among patients with both colorectal cancer and diabetes in Korea, those who had a high adherence to their oral diabetes medication had a significantly reduced risk of overall mortality compared with those with lower adherence.

1 Jun 2020

New genetic engineering technique sets the stage for advances in medicine and beyond

From bacteria-made insulin that obviates the use of animal pancreases to a better understanding of infectious diseases and improved treatments, genetic engineering of bacteria has redefined modern medicine. Yet, serious limitations remain that hamper| progress in numerous other areas.

30 May 2020

Researchers identify risk factors for fatty liver disease

Researchers at Massachusetts General Hospital have uncovered an unexpected connection between an imbalance of electrons in liver cells and many metabolic problems that increase the risk for conditions such as cardiovascular disease and fatty liver disease.

29 May 2020

Using electric current to directly control gene expression

A team of researchers led by ETH professor Martin Fussenegger has succeeded in using an electric current to directly control gene expression for the first time.

28 May 2020

KHN’s ‘What the Health?’: Still seeking a federal coronavirus strategy

The Trump administration sent its COVID-19 testing strategy plan to Congress, formalizing its policy that most testing responsibilities should remain with individual states.

28 May 2020

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

For patients with diabetes - especially those with lower incomes - preventive drug lists (PDLs) of essential medications available with no deductible can reduce out-of-pocket costs while increasing use of important treatments, reports a study in a June supplement to Medical Care.

27 May 2020

A new therapeutic approach to improve the health of diabetic patients

Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin.

27 May 2020

New book series brings updated reviews on diabetes and obesity

Frontiers in Clinical Drug Research - Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases - diabetes and obesity.

27 May 2020

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

A new federal grant will allow young scientists to delve into the mechanisms of emotional eating and preeclampsia and other disorders not considered "classic" metabolic diseases.

26 May 2020

Study reveals mechanism involved in the development of diabetes, fatty liver

A research group including Professor OGAWA Wataru (Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine) and Project Associate Professor HOSOOKA Tetsuya (Division of Development of Advanced Therapy for Metabolic Disease, Kobe University Graduate School of Medicine) has clarified the mechanism underlying the development of diabetes and non-alcoholic steatohepatitis (NASH), a severe form of fatty liver.

22 May 2020

Drug combination could eliminate side effects of largely abandoned diabetes treatment

A new UT Southwestern study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side effects.

20 May 2020

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

For years, surgeons have operated on pancreatic cancer patients to remove what they thought was a localized tumor only to discover that the disease had spread to other, inoperable parts of the body. Now, a City of Hope molecular scientist thinks he may have found a way to prevent ineffective surgeries and prolong the lives of these patients.

18 May 2020

Transition to virtual care during COVID-19 does not limit glycemic outcomes of diabetes inpatients

Data collected over a 15-week period showed that using virtual care to manage diabetes patients in the hospital does not have a negative impact on their glycemic outcomes.

15 May 2020

Repurposed drug normalizes body weight, reverses metabolic damage in obese mice

An off-label experiment in mice using disulfiram, which has been used to treat alcohol use disorder for more than 50 years, consistently normalized body weight and reversed metabolic damage in obese middle-aged mice of both sexes.

14 May 2020

A deep look into hormone-producing cells of the gut

Researchers from the Hubrecht Institute and Utrecht University generated an in-depth description of the human hormone-producing cells of the gut, in a large collaborative effort with other research teams. The results are presented in the scientific journal Cell on the 13th of May.

13 May 2020

C-Path, Provention Bio collaborate to improve scientific community's insight into type 1 diabetes

The Critical Path Institute and Provention Bio, Inc. are proud to announce their collaboration to significantly improve the scientific community's insight into type 1 diabetes through Provention's contribution of data from the Phase III Protégé study of teplizumab to the T1D Trial Outcome Measures Initiative integrated database.

13 May 2020

Insulin News and Research

Further Reading

Cone snail venom produces new type of insulin

Breakthrough discovery could lead to treatment of Fragile X syndrome

Cone snail insulin research could jumpstart the development of better diabetes treatments

Out-of-pocket health care costs for patients with type 1 diabetes is $2,500 a year, study reveals

Oral antidiabetics improve outcomes in diabetics with colorectal cancer

New genetic engineering technique sets the stage for advances in medicine and beyond

Researchers identify risk factors for fatty liver disease

Using electric current to directly control gene expression

KHN’s ‘What the Health?’: Still seeking a federal coronavirus strategy

No-deductible preventive drugs can reduce out-of-pocket costs for diabetic patients

A new therapeutic approach to improve the health of diabetic patients

New book series brings updated reviews on diabetes and obesity

New NIH grant will help Pennington Biomedical scientists to study metabolic diseases

Study reveals mechanism involved in the development of diabetes, fatty liver

Drug combination could eliminate side effects of largely abandoned diabetes treatment

Novel microRNA biomarker could help detect lymph node metastases in pancreatic cancer patients

Transition to virtual care during COVID-19 does not limit glycemic outcomes of diabetes inpatients

Repurposed drug normalizes body weight, reverses metabolic damage in obese mice

A deep look into hormone-producing cells of the gut

C-Path, Provention Bio collaborate to improve scientific community's insight into type 1 diabetes

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