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New study finds familial risk and heritability of cancer among twins

A large new study of twins has found that having a twin sibling diagnosed with cancer poses an excess risk for the other twin to develop any form of cancer. Among the 23 different types of cancer studied, an excess familial risk was seen for almost all of the cancers, including common cancers such as breast and prostate cancer, but also more rare cancers such as testicular cancer, head and neck cancer, melanoma, ovarian and stomach cancer.

6 Jan 2016

New study describes STING protein's role in potential suppression of colorectal cancer

A new study published today by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine reports on a key finding about the immune system's response to tumor development following studies on colorectal cancer.

4 Jan 2016

IASLC lauds FDA approval of alectinib for lung cancer treatment

The International Association for the Study of Lung Cancer (IASLC) is once again gratified to see the approval of a new second-generation lung cancer treatment that can help many patients in their battle against the disease.

24 Dec 2015

Shells of plant virus trigger immune system to wipe out tumors, provide protection against metastases

The shells of a common plant virus, inhaled into a lung tumor or injected into ovarian, colon or breast tumors, not only triggered the immune system in mice to wipe out the tumors, but provided systemic protection against metastases, researchers from Case Western Reserve University and Dartmouth University report.

23 Dec 2015

UB study traces how enigmatic molecules help cancer self-destruct

You've probably never heard of "sphingolipids" before. But these curiously named organic compounds play a vital role in one of humanity's most well-known diseases: cancer.

18 Dec 2015

Family members of CUP patients at higher risk of developing CUP themselves

Cancer usually begins in one location and then spreads, but in 3 percent to 5 percent of cancer patients, the tissue where a cancer begins is unknown. In these individuals a cancer diagnosis is made because it has metastasized to other sites. Patients with these so-called "cancers of unknown primary," or CUP, have a very poor prognosis, with a median survival of three months.

18 Dec 2015

ACS, Alliance begin work on second volume of manual for cancer surgery

The American College of Surgeons and the Alliance for Clinical Trials in Oncology announced that they have begun work on the second volume of a comprehensive, evidence-based examination of cancer surgery techniques and recommendations.

17 Dec 2015

Reducing cost for screening does not increase colorectal cancer screening rates

Making colonoscopy available at no cost to eligible Medicare beneficiaries under the Affordable Care Act did not increase the number of people in this target population who regularly undergo the procedure, says a new large scale national study from University Hospitals Case Medical Center Seidman Cancer Center.

17 Dec 2015

Discovery could pave way for targeted therapies to treat penile cancer

Researchers have identified potential genetic alterations in penile cancer that could pave the way for targeted treatments.

15 Dec 2015

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

Considerable racial disparities exist in surgical outcomes for black and Hispanic patients undergoing major cancer and non-cancer surgeries in U.S. hospitals, even among institutions that have already enrolled in a national surgical quality improvement initiative.

9 Dec 2015

RTFCCR grant supports ASCOLT study that evaluates effectiveness of Aspirin in colorectal cancer patients

Rising Tide Foundation for Clinical Cancer Research, an international private foundation based in Switzerland, has awarded a US $800,000 grant to be released over two years for the ASCOLT study conducted by Dr John Chia, Senior Consultant Medical Oncologist at the Division of Medical Oncology, National Cancer Centre Singapore.

9 Dec 2015

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Scientists have shown for the first time why loss of the enzyme CD73 in human cancer promotes tumor progression.

8 Dec 2015

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

In the five decades since camptothecin was first isolated from the bark of a tree used in traditional Chinese medicine and identified as a powerful anticancer agent, several thousand chemicals with similar structures and functions have been investigated. And while two of these analog compounds, irinotecan and topotecan, have been approved in the U.S. as treatments for cancer, both are associated with significant shortcomings.

26 Nov 2015

Opdivo (nivolumab) approved to treat patients with advanced renal cell carcinoma

The U.S. Food and Drug Administration today approved Opdivo (nivolumab) to treat patients with advanced (metastatic) renal cell carcinoma, a form of kidney cancer, who have received a certain type of prior therapy.

23 Nov 2015

NYC’s colorectal cancer screening rates boosted and racial disparities eliminated

A concerted effort to increase colorectal cancer screening rates led to a dramatic increase in NYC screening colonoscopy rates among average-risk men and women and eliminated racial/ethnic disparities in screening

23 Nov 2015

New coalition formed to boost colorectal cancer screening rates in New York City

A coalition formed by the New York City Department of Health and Mental Hygiene which included a team from Mount Sinai to increase colorectal cancer screening rates in New York City resulted in a 40 percent increase in screening rates over four years.

23 Nov 2015

Researchers suggest new way to target cancer protein

For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor -- it performs the crucial task of helping convert DNA into the RNA instructions used to make new proteins.

19 Nov 2015

Identifying new mechanism for aspirin in cancer prevention

Aspirin has been shown to decrease the risk of colorectal cancer and possibly other cancers. However, the risk of side effects, including in some cases severe gastrointestinal bleeding, makes it necessary to better understand the mechanisms by which aspirin acts at low doses before recommending it more generally as a preventative, says Cornelia Ulrich, PhD, Senior Director of Population Sciences at Huntsman Cancer Institute in Salt Lake City.

19 Nov 2015

New approach helps Group Health to increase rates of lifesaving screening for colon cancer

Mailing yearly stool kits--an alternative to the often-dreaded colonoscopy--has helped Group Health to boost rates of lifesaving screening for colon cancer, according to new research from Group Health Research Institute.

17 Nov 2015

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

The International Association for the Study of Lung Cancer commends the U.S. Food and Drug Administration's (FDA) decision to grant accelerated approval for osimertinib (Tagrisso), an oral medication for advanced non-small cell lung cancer (NSCLC) patients with a specific epidermal growth factor receptor (EGFR) mutation (T790M) and following progression after previous EGFR inhibitor therapies.

17 Nov 2015

Colon News and Research

New study finds familial risk and heritability of cancer among twins

New study describes STING protein's role in potential suppression of colorectal cancer

IASLC lauds FDA approval of alectinib for lung cancer treatment

Shells of plant virus trigger immune system to wipe out tumors, provide protection against metastases

UB study traces how enigmatic molecules help cancer self-destruct

Family members of CUP patients at higher risk of developing CUP themselves

ACS, Alliance begin work on second volume of manual for cancer surgery

Reducing cost for screening does not increase colorectal cancer screening rates

Discovery could pave way for targeted therapies to treat penile cancer

Racial disparities exist for black and Hispanic patients undergoing major surgeries in U.S. hospitals

RTFCCR grant supports ASCOLT study that evaluates effectiveness of Aspirin in colorectal cancer patients

Scientists reveal why loss of CD73 enzyme in human cancer promotes tumor progression

Novel anticancer agent appears to have greater potency, longer efficacy than irinotecan and topotecan

Opdivo (nivolumab) approved to treat patients with advanced renal cell carcinoma

NYC’s colorectal cancer screening rates boosted and racial disparities eliminated

New coalition formed to boost colorectal cancer screening rates in New York City

Researchers suggest new way to target cancer protein

Identifying new mechanism for aspirin in cancer prevention

New approach helps Group Health to increase rates of lifesaving screening for colon cancer

IASLC commends FDA's decision to grant accelerated approval for new lung cancer therapy

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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