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New mRNA-based malaria vaccine shows promise in preclinical trials

Trans-Tasman research collaborators from Te Herenga Waka-; Victoria University of Wellington's Ferrier Research Institute and the Malaghan Institute of Medical Research in New Zealand, and the Peter Doherty Institute for Infection and Immunity in Australia have developed an mRNA-based vaccine that can effectively target and stimulate protective immune cell responses against the malaria-causing parasite Plasmodium in preclinical models.

20 Jul 2023

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

People who contract COVID-19 but never develop symptoms – the so-called super dodgers – may have a genetic ace up their sleeve.

20 Jul 2023

Targeting the "don't eat me" signal may improve immunotherapy for glioblastoma

"Don't eat me!" That's how one might translate the signal that the cancer cells in a glioblastoma send to the macrophages (white blood cells specialized in removing dead and dying cellular matter) in the brain.

19 Jul 2023

Study shows how NSAIDs exacerbate C. difficile infections

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide?

19 Jul 2023

New biosensor could quickly and inexpensively identify people at risk for osteoporosis

As life expectancy increases worldwide, age-associated diseases such as osteoporosis are having an increasing impact.

19 Jul 2023

Espresso compounds inhibit tau protein aggregation in preliminary in vitro tests

Whether enjoyed on its own or mixed into a latte, Americano or even a martini, espresso provides an ultra-concentrated jolt of caffeine to coffee lovers.

19 Jul 2023

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

Researchers have identified a potential immune biomarker associated with pulmonary TB in active patients compared to controls.

19 Jul 2023

Study reveals molecular mechanisms of H. pylori-induced gastric carcinogenesis

Helicobacter pylori (H. pylori) infections are commonly associated with abdominal pain, bloating, and acidity. Clinical evidence suggests that infection with H. pylori cagA+ strains dramatically increases the risk of developing gastric cancer.

18 Jul 2023

Study finds link between DHX9 gene mutations and neurodevelopmental disorders

A group of 20 patients with undiagnosed neurodevelopmental disorders ranging from severe to mild has now received a genetic diagnosis thanks to an international team of researchers at the GREGoR Research Center at Baylor College of Medicine, the Chinese University of Hong Kong, the German Mouse Clinic and collaborating institutions.

18 Jul 2023

CEPI and HMRI partner to accelerate development of pandemic vaccines

CEPI, the Coalition for Epidemic Preparedness Innovations, and the Houston Methodist Research Institute (HMRI), have today announced a partnership to combine cutting-edge artificial intelligence (AI) technology with established laboratory techniques to speed up development of future vaccines against novel viral threats (also known as Disease X).

18 Jul 2023

Immunomodulatory effects of PFAS can impair health

Because they are persistant, per- and polyfluoroalkyl substances (PFAS) are also known as "chemicals for eternety".

18 Jul 2023

IU researchers present groundbreaking findings at Alzheimer's conference

Researchers from Indiana University School of Medicine had a large presence and leadership role at the 2023 Alzheimer's Association International Conference in Amsterdam, Netherlands, with involvement in more than 150 presentations at the four-day meeting.

18 Jul 2023

Tight junctions between cells may play a critical role in gastrulation in human embryos

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo.

18 Jul 2023

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

17 Jul 2023

American Heart Association calls for more research on e-cigarettes

Research increasingly reveals health risks of e-cigarette use, and more studies are needed about the long-term impact e-cigarettes may have on the heart and lungs, according to a new scientific statement from the American Heart Association published today in the Association's flagship journal Circulation.

17 Jul 2023

Machine learning's potential for rapid LRTI diagnosis

A team of researchers evaluated the use of prediction models in LRTI diagnosis.

17 Jul 2023

MGI Empowers Life Sciences Industry with Revolutionary What If Campaign at XXIIIrd International Congress of Genetics

MGI Tech Co. Ltd. (MGI), a company committed to building core tools and technology to lead life science, today announced the launch of a global brand campaign titled “What If?” at the XXIII International Congress of Genetics (ICG), a five-yearly conference to bring together the international genetics community from around the world.

From MGI 17 Jul 2023

Wondfo training center is jointly launched in the University of Nairobi

In early July, Wondfo, collaborating with the University of Nairobi in Kenya, officially launched a laboratory training center.

17 Jul 2023

Stable nanoparticles train the immune system to fight cancer

Over the past decade, researchers have sought more effective and enduring cancer treatments. Among the wide variety of immunotherapies, Stimulator of Interfron Genes activation (STING agonism) has emerged as a particularly promising approach that harnesses a patient’s immune system to combat tumors throughout the body.

17 Jul 2023

BU professor receives NIH grant to study impact of PFAS toxicants on the vascular system

Noyan Gokce, MD, professor of medicine at Boston University Chobanian & Avedisian School of Medicine, has been awarded a $453,750 National Institutes of Health (NIH) R-21 grant for his research study "Impact of Per/Polyfluoroalkyl (PFAS) pollutants on vascular disease mechanisms."

14 Jul 2023

Laboratory News and Research

New mRNA-based malaria vaccine shows promise in preclinical trials

Study reveals a genetic basis for asymptomatic SARS-CoV-2 infection

Targeting the "don't eat me" signal may improve immunotherapy for glioblastoma

Study shows how NSAIDs exacerbate C. difficile infections

New biosensor could quickly and inexpensively identify people at risk for osteoporosis

Espresso compounds inhibit tau protein aggregation in preliminary in vitro tests

Study identifies potential immune biomarker for pulmonary tuberculosis: a step towards early detection

Study reveals molecular mechanisms of H. pylori-induced gastric carcinogenesis

Study finds link between DHX9 gene mutations and neurodevelopmental disorders

CEPI and HMRI partner to accelerate development of pandemic vaccines

Immunomodulatory effects of PFAS can impair health

IU researchers present groundbreaking findings at Alzheimer's conference

Tight junctions between cells may play a critical role in gastrulation in human embryos

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

American Heart Association calls for more research on e-cigarettes

Machine learning's potential for rapid LRTI diagnosis

MGI Empowers Life Sciences Industry with Revolutionary What If Campaign at XXIIIrd International Congress of Genetics

Wondfo training center is jointly launched in the University of Nairobi

Stable nanoparticles train the immune system to fight cancer

BU professor receives NIH grant to study impact of PFAS toxicants on the vascular system

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