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Phase I cancer findings under-reported

Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals - a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out today (Mon., Aug, 22) online in Cancer.

22 Aug 2005

Cancer Research Technology licenses novel cancer diagnostic markers

Cancer Research Technology Limited announced today that they have entered into a worldwide license agreement with TriPath Imaging, Inc.

22 Aug 2005

Children who eat fries raise their risk of breast cancer later in life

According to a new study very young children who eat french fries frequently have a much higher risk of breast cancer as adults.

21 Aug 2005

Losing weight cuts breast cancer risk

An international team of scientists has found that young women who carry a breast cancer gene, can reduce their risk of the disease by up to 65% by attaining a healthy bodyweight.

21 Aug 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

High rate of heart attack amongst ethnic minorities in Scotland

The incidence of heart attack amongst Scots of Indian and Pakistani origin is 60-70% higher when compared with non-South Asians, a new report led by the University of Edinburgh has shown.

18 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Defects in newly discovered pathway may be an overlooked cause of anemia

Researchers studying zebrafish that die from anemia have discovered a new pathway for the synthesis of heme, the deep red, iron-containing molecule that is a component of hemoglobin and myoglobin.

18 Aug 2005

Anxiety disorders can compromise success of alcohol-dependence treatment

Individuals who have an anxiety disorder when starting treatment for alcohol dependence have a significantly greater risk for relapse to drinking within four months, according to researchers at the University of Minnesota.

18 Aug 2005

President Bush's No Child Left Behind act appears to be leaving children behind

The nation's main program for educating the disadvantaged, Title I, is hampered by loopholes that prevent it from fulfilling its mission, according to a new study.

18 Aug 2005

Separate studies produce conflicting results on race and gender disparities in U.S. health system

Two newly released studies in the U.S. have to some extent come to conflicting results. According to one study, by researchers at Emory University, attempts over the last decade to address race and gender disparities in the treatment of U.S. patients hospitalized for heart attacks, still in some respects raise cause for concern.

18 Aug 2005

U.S. beverage industry praised for helping in childhood obesity battle

The American Beverage Association (ABA) has approved a policy aimed at limiting the sale of soft drinks in school vending machines as the nation fights obesity.

17 Aug 2005

First clear evidence that olfaction is uniquely a "dual" sense

In the August 18, 2005, issue of Neuron, researchers report that the smell of chocolate activated different brain regions according to whether the odor was introduced into the olfactory system through the mouth or through the nose.

17 Aug 2005

C. elegans has similar virus-fighting mechanism as humans and can be used in research

Researchers at the University of California, Riverside have discovered that a simple worm, called C. elegans, makes an excellent experimental host for studying some of the most virulent viruses that infect humans.

17 Aug 2005

Treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race

Despite a decade of initiatives to remedy health disparities in cardiovascular medicine, at least some aspects of the treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race, according to a study by researchers at Emory University in collaboration with Yale University and other centers.

17 Aug 2005

Doctors should not shy away from giving 80 year olds heart bypass surgery

...suggests research published ahead of print in Heart. Most of those who received the treatment were still alive five years later and had half the risk of death of their peers in the general population, the research reveals.

17 Aug 2005

Loss of a gene called p63 accelerates aging in mice

Researchers have discovered that the loss of a gene called p63 accelerates aging in mice. Similar versions of the gene are present in many organisms, including humans. Therefore, the p63 gene is likely to play a fundamental biological role in aging-related processes.

17 Aug 2005

Women whose breast cancer is detected by mammography have a significantly better prognosis

Women whose breast cancer was detected by screening mammography had a significantly better prognosis than those whose cancer was found another way - even if the cancer had already spread to their lymph nodes, say researchers at The University of Texas M. D. Anderson Cancer Center who looked at outcomes from randomized screening studies of more than 150,000 women.

17 Aug 2005

Biochemical switch that affects how neurons fire in a part of the brain associated with learning

Researchers at UT Southwestern Medical Center have identified a biochemical switch that affects how neurons fire in a part of the brain associated with learning, findings that may aid in understanding schizophrenia and Alzheimer's disease.

17 Aug 2005

Common non-aspirin painkillers linked to high blood pressure in women

Women who consume higher doses of non-aspirin painkillers are much more likely to develop high blood pressure than women who do not use them, according to research reported in Hypertension: Journal of the American Heart Association.

17 Aug 2005