Research News and Research

RSS

Twins, triplets have greater chance of birth defects

Twins, triplets and other multiples have a nearly 50 percent greater chance of being born with birth defects, and boys tend to be more at risk than girls, according to two population-based studies conducted at the University of Florida.

5 Dec 2005

Unexpected link between muscular dystrophy and muscle wasting associated with cancer

A new study provides important insight into the mechanisms of a muscle wasting disorder that interferes with treatment for cancer and has a negative impact on patient survival.

5 Dec 2005

HRAS mutation analysis in Costello Syndrome

Gene mutations in the HRAS sequence are present in most patients affected with Costello syndrome, according to a new study in the American Journal of Medical Genetics. The mutations occurred de novo in patients, meaning, they were not observed in their parents' genes.

5 Dec 2005

CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD

Gene is associated with increased risk of precursor of macular degeneration A variant in a gene called Complement Factor H (CFH) appears to contribute to the increased risk of advanced age-related macular degeneration (AMD) largely or entirely through its impact on the development of a precursor of advanced AMD called soft drusen (small yellowish, extracellular deposits of lipid, protein and cellular debris in the back of the eye), according to a multinational team of researchers.

2 Dec 2005

Discovery of genetic mechanism that causes new arteries to grow in response to blocked arteries

Researchers at the San Francisco VA Medical Center have uncovered part of the genetic mechanism that causes new arteries to grow in response to blocked arteries.

2 Dec 2005

Fast-tracked screening for Chlamydia in UK

Young women asking for the morning-after pill at pharmacies will be offered fast-tracked screening for Chlamydia, the UK's most common sexually transmitted infection, in a University of Manchester study.

From The University of Manchester 2 Dec 2005

Findings may help in development of new anti-inflammatory compounds

Virginia Commonwealth University researchers studying the enzyme that triggers inflammation have found that it may be a target for a new class of anti-inflammatory drugs to treat arthritis, asthma, multiple sclerosis, lung and colon cancers and Alzheimer's disease.

2 Dec 2005

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Disruption of normal gene interaction linked to schizophrenia

Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a group of investigators that includes a scientist now at St. Jude Children's Research Hospital.

2 Dec 2005

Depressed heart patients skip medications

Recent studies conducted at the San Francisco VA Medical Center suggest two possible mechanisms for the widely recognized link between depression and adverse outcomes in patients with coronary heart disease: lack of adherence to medication regimens and increased levels of norepinephrine, a stress hormone.

2 Dec 2005

Schizotypy, creativity and mating success in humans

The more creative a person is, the more sexual partners they are likely to have, according to a pioneering study which could explain the behaviour of notorious womanisers such as poets Lord Byron and Dylan Thomas.

2 Dec 2005

Mycophenolate mofetil helps treat lupus patients

Treating lupus patients suffering from kidney inflammation with a medicine known as mycophenolate mofetil may be more effective in inducing remission than treating them with the standard regimen of intravenous cyclophosphamide (Cytoxan), a new clinical trial indicates.

2 Dec 2005

Childcare helps reduce stress levels for mums and children

Low job satisfaction in working mothers increases the stress levels of their children, but spending longer in childcare can help overcome these effects, new research has shown.

2 Dec 2005

Childbirth not linked to urinary incontinence

Postmenopausal women who have given birth vaginally do not appear to suffer from urinary incontinence at higher rates than their sisters who have never given birth, according to a University of Rochester Medical Center study published in the December Obstetrics and Gynecology journal.

2 Dec 2005

Bisphenol A (BPA) has been linked to damage in developing brain tissue

The chemical bisphenol A (BPA), widely used in products such as food cans, milk container linings, water pipes and even dental sealants, has now been found to disrupt important effects of estrogen in the developing brain.

2 Dec 2005

Carvedilol, a cardiovascular drug, may improve heart failure and help prevent sudden death

Research shows that Carvedilol, a cardiovascular drug, could be useful in reducing cardiac death in high risk patients with prior myocardial infarction and/or heart failure and also in reducing the incidence and/or preventing the occurrence of atrial fibrillation in a number of clinical situations.

2 Dec 2005

Herceptin - can healthcare afford this expensive drug?

New research into the cost of using the breast cancer drug Herceptin warns that healthcare authorities and the organisations advising them should not rush to prescribe it for early breast cancer without working out extremely carefully the budget implications and cost-effectiveness of the drug.

2 Dec 2005

Breast CT may be better than mammography at detecting breast lesions

Breast CT, an investigational technology for early breast cancer detection, may be better than mammography at detecting breast lesions and is much more comfortable for women, researchers from the University of California, Davis reported at the annual meeting of the Radiological Society of North America in Chicago.

2 Dec 2005

Cellular and molecular mechanisms that accelerate the development and progression of atherosclerosis

A McMaster University study on atherosclerosis will be featured on the cover of the December issue of the high impact American Heart Association scientific journal, Arteriosclerosis, Thrombosis and Vascular Biology.

2 Dec 2005

New alcohol biomarker test lowers the cost of caring for patients with chronic illnesses

Adding a new alcohol biomarker test to patients' revelations about their drinking habits could lower the cost of caring for patients with chronic illnesses like diabetes and high blood pressure, a health economics analysis finds.

2 Dec 2005