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Novel quantitative method may reduce or eliminate need for invasive biopsies

Scientists have identified a quantitative method to measure changes in biomarkers, which may reduce or eliminate the need for invasive biopsies. The method, described in the February 2016 issue of The FASEB Journal uses a novel chimera design of DNA and small DNA with a companion contrast agent to allow antibodies to cross cellular membranes.

8 Feb 2016

Study provides window into the brain changes that link mindfulness meditation with health-related benefits

Over the past decade, mindfulness meditation has been shown to improve a broad range of health and disease outcomes, such as slowing HIV progression and improving healthy aging. Yet, little is known about the brain changes that produce these beneficial health effects.

5 Feb 2016

Study examines links between spending on social services and AIDS deaths in U.S.

Despite considerable advances in the prevention and treatment of HIV/AIDS over the past 30 years, HIV infection rates have remained stagnant in the United States for the past decade. A study by researchers at the Yale Global Health Leadership Institute examines links between spending on social services and public health and AIDS deaths in the United States.

4 Feb 2016

Innate lymphoid cells get destroyed in patients infected with HIV

A research project headed by Henrik Kloeverpris, a postdoc at the Department of Immunology and Microbiology at the University of Copenhagen, shows that the so-called ILCs (innate lymphoid cells) - a component of the immune system crucial to maintaining immune system balance - are destroyed in patients infected with HIV.

4 Feb 2016

Cistus extracts attack HIV and Ebola viruses

Scientists at the Helmholtz Zentrum München discover that extracts of the medicinal plant Cistus incanus (Ci) prevent human immunodeficiency viruses from infecting cells. Active antiviral ingredients in the extracts inhibit docking of viral proteins to cells. Antiviral activity of Cistus extracts also targets Ebola- and Marburg viruses.

3 Feb 2016

Research: Adenosine deaminase may help activate immune system against HIV

New research findings published in the February 2016 issue of the Journal of Leukocyte Biology, suggest that a new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug.

3 Feb 2016

Study shows several Envigo rat models susceptible to genital HSV-2 infection

A scientific collaboration between Envigo and the Department of Infectious Disease at the University of Gothenburg, Sweden has unveiled study findings into rat models and their susceptibility to intra-vaginal herpes simplex virus-2 (HSV-2) infection.

2 Feb 2016

LSTM-led researchers publish findings from lung health study in international respiratory journal

A team of investigators led from LSTM has published findings from a lung health study to determine the prevalence of lung disease among adults in Malawi, in the leading international respiratory journal, the American Journal of Respiratory and Critical Care Medicine.

2 Feb 2016

Alternative splicing: a new approach to drug development? An interview with Lucy Donaldson

RNA is becoming an interesting drug target as it takes possible intervention back one step to the synthesis of a target protein, instead of trying to block or inhibit a process.

1 Feb 2016

HIV protein alters activity of networked neurons

Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin that continues to be produced despite treatment with antiretroviral therapy.

31 Jan 2016

EC approves expanded use of Daklinza (daclatasvir) for patients with chronic HCV and HIV co-infection

Bristol-Myers Squibb today announced that the European Commission has approved the expanded use of Daklinza, a first-in-class oral, once-a-day pill used in combination with other treatments as an option for adult patients with chronic hepatitis C virus infection who are co-infected with HIV or who have had a prior liver transplant.

30 Jan 2016

HIV persists in the body despite effective antiretroviral therapy

A team of international scientists led by Northwestern University found that HIV is still replicating in lymphoid tissue, even when it is undetectable in the blood of patients on antiretroviral drugs.

28 Jan 2016

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

Flow Cytometry, the measurement of various cellular characteristics as they flow through a measuring apparatus, has so many applications.

From Beckman Coulter Life Sciences - Centrifugation 27 Jan 2016

Ageing 2016 summit to explore various aspects of processes, research on ageing and senescence

Ageing 2016 will be held from February 9 to 11, 2016 at Cineworld: The O2 Peninsula Square London SE10 0DX United Kingdom. The annual international summit will look at the various aspects of processes and research involved in ageing and senescence.

25 Jan 2016

Scientists demonstrate effectiveness of ART in HIV-infected infants

Recent clinical trials conducted in South Africa have established that babies born with HIV should be treated with antiretroviral therapy (ART) as early as possible, since earlier treatment significantly decreases their mortality and morbidity rates.

25 Jan 2016

Opt-out HIV testing could substantially increase patient acceptance of HIV testing

How you offer patients an HIV test has a significant impact on the likelihood of them accepting tests, finds a study published by The BMJ today.

21 Jan 2016

Johnson & Johnson joins industry-wide call to address growing problem of antimicrobial resistance

Johnson & Johnson today announced it has joined more than 80 companies and organizations in signing the Declaration on Combating Antimicrobial Resistance (AMR), an industry-wide call to action announced at the World Economic Forum in Davos, Switzerland.

21 Jan 2016

Estrogen helps women fight flu virus better than men

Estrogen dramatically reduced the amount of flu virus that replicated in infected cells from women but not from men, a new study by researchers at the Johns Hopkins Bloomberg School of Public Health shows.

20 Jan 2016

New technique may accelerate development of novel vaccines

An interdisciplinary team of Oxford University researchers has devised a new technique to speed up the development of novel vaccines.