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Study finds multiple genetic variations can contribute to common childhood obesity

A new study uncovers multiple genetic variations associated with common childhood obesity. The research, published by Cell Press on October 14th in the American Journal of Human Genetics, is likely to guide future studies aimed at characterizing the affected genes and unraveling the complex biology that underlies childhood obesity.

15 Oct 2010

Scientists discover 'switch' mechanism of lymphatic and blood vessel cells

Scientists at the University of East Anglia have made an important breakthrough in the way anti-cancer drugs are tested. A tumour cannot grow to a large size or spread until it has developed its own blood supply and leading research has looked for a way of halting capillary formation to stop tumours taking hold.But new findings published today in the Journal of Cell Science have shown that scientists testing such treatments may not have been studying exactly what they thought they were.

14 Oct 2010

Patient-specific experimental vaccine to prevent recurrence of glioblastoma

Mary Lee's primary care physician is also a family friend. When he walked into the exam room in October 2006 with tears in his eyes, she knew something serious was wrong. But she was shocked to learn she had a brain tumor - and later found out it was the most aggressive malignant type, a glioblastoma multiforme.

14 Oct 2010

Scientists identify root cause of chromosomal errors and gene diversity

A team led by a scientist at the University of Pittsburgh School of Medicine has discovered a regulatory protein that influences where genetic material gets swapped between maternal and paternal chromosomes during the process of creating eggs and sperm. The findings, which shed light on the roots of chromosomal errors and gene diversity, appear in tomorrow's issue of Nature.

14 Oct 2010

NIH awards grant to Bavarian to advance early research in filoviruses

Bavarian Nordic A/S announced today that the company has received funding from the U.S. National Institutes of Health (NIH) to advance its early research in filoviruses (Ebola and Marburg virus).

14 Oct 2010

Dyadic International receives sixth USPTO patent

Dyadic International, Inc. a global biotechnology company focused on the discovery, development, manufacture and sale of enzyme and protein products and solutions for the bioenergy, industrial enzyme and biopharmaceutical industries, announced today that it has been issued U.S. Patent No. 7,794,962 by the United States Patent and Trademark Office.

14 Oct 2010

Research shows honey bees change their circadian rhythms

Unlike humans, honey bees, when thrown into highly time-altered new societal roles, are able to alter their biological rhythms with alacrity, enabling them to make a successful "quick switch" in their daily routines, according to research carried out at the Hebrew University of Jerusalem.

13 Oct 2010

Cancer Research UK launches programme to turn genetic revolution into better treatment for cancer patients

Cancer Research UK has launched a multimillion pound programme, alongside the Technology Strategy Board's Innovation Platform, to help turn the genetic revolution into better treatment for cancer patients.

13 Oct 2010

Scientists identify gene that could predict breast cancer patients' response to tamoxifen

Scientists have identified a gene which could help predict whether a breast cancer patient will respond to taking tamoxifen. The study, published in the British Journal of Cancer today (Wednesday), showed a potential link between the activity of a gene called BCAR4 and the likelihood that a breast cancer tumour will not respond to tamoxifen - widely used to treat women with breast cancer.

13 Oct 2010

Imprime PGG and cetuximab increase overall response rate in metastatic colorectal cancer

A combination of Biothera's Imprime PGG and cetuximab (Erbitux) doubled the overall response rates for second- and third-line metastatic colorectal cancer patients participating in a Phase Ib/IIa clinical trial. The completed trial results were released yesterday at the 35th European Society for Medical Oncology (ESMO) Congress.

13 Oct 2010

Scientists design synthetic molecule to protect liver cancer cells from toxic effects of chemotherapy

Scientists have found that a synthetic molecule they designed can block activation of a gene in liver cancer cells, halting a process that allows some of those cancer cells to survive chemotherapy.

13 Oct 2010

Defect in 21st amino acid leads to progressive brain atrophy: Study

A research team at Ben-Gurion University of the Negev and Soroka University Medical Center in Beer-Sheva, Israel has detected a genetic mutation resulting in a progressive disease of severe mental retardation and epilepsy beginning at infancy. The research was just published in the American Journal of Human Genetics.

13 Oct 2010

HSV1716 clinical trial for childhood cancer receives FDA grant

A clinical trial testing a genetically reprogrammed herpes simplex virus as treatment for deadly forms of childhood cancer has received a U.S. Food and Drug Administration grant to support the research.

13 Oct 2010

Scientists identify mutant protein in type 2 diabetes

University of Michigan scientists have identified events inside insulin-producing pancreatic cells that set the stage for a neonatal form of non-autoimmune type 1 diabetes, and may play a role in type 2 diabetes as well. The results point to a potential target for drugs to protect normally functioning proteins essential for producing insulin.

13 Oct 2010

Engaging in healthy lifestyle can help women with family history control breast cancer risk

Having a family history of breast cancer can lead some women to wonder if the risk is out of their control. However, a study of more than 85,000 postmenopausal women, published in BioMed Central's open access journal Breast Cancer Research, observed that regular physical activity, maintaining a healthy weight, and drinking less alcohol lowers breast cancer risk for those with and without a family history of the disease.

12 Oct 2010

Global study finds new set of genes associated with body fat distribution and obesity

Two major international studies looking at data from a quarter of a million people around the globe have found a new set of genes associated with body fat distribution and obesity. Researchers at 280 institutions worldwide, including Albert Einstein College of Medicine of Yeshiva University, conducted the studies. The research, published in the October 10 online edition of Nature Genetics, sheds light on the biological processes involved in body fat distribution, possibly leading to new ways of treating obesity.

12 Oct 2010

Researchers develop new method to identify chemical histone modifications

Test system on Drosophila should provide the key to histone function. The genetic inherited material DNA was long viewed as the sole bearer of hereditary information. The function of its packaging proteins, the histones, was believed to be exclusively structural. Additional genetic information can be stored, however, and passed on to subsequent generations through chemical changes in the DNA or histones. Scientists from the Max Planck Institute for Biophysical Chemistry in Göttingen have succeeded in creating an experimental system for testing the function of such chemical histone modifications and their influence on the organism.

12 Oct 2010

Healthy lifestyle can reduce breast cancer risk in women with family history

Having a family history of breast cancer can lead some people to wonder if their risk is out of their control. However, a study of more than 85,000 postmenopausal women observed that regular physical activity, maintaining a healthy weight, and drinking less alcohol lowers breast cancer risk for women with, and without a family history of the disease.

12 Oct 2010

Persistent exposure to light at night leads to weight gain

Persistent exposure to light at night may lead to weight gain, even without changing physical activity or eating more food, according to new research in mice.

12 Oct 2010

Biologists recommend virtual institute for RNA research

A Europe-wide network of labs focusing on RNA research is needed to make the most of RNA's high potential for treating a wide range of diseases. The recommendation for this virtual research institute comes from a panel of biologists at the European Science Foundation in a report published today, 'RNA World: a new frontier in biomedical research'.

12 Oct 2010

Genes News and Research

Study finds multiple genetic variations can contribute to common childhood obesity

Scientists discover 'switch' mechanism of lymphatic and blood vessel cells

Patient-specific experimental vaccine to prevent recurrence of glioblastoma

Scientists identify root cause of chromosomal errors and gene diversity

NIH awards grant to Bavarian to advance early research in filoviruses

Dyadic International receives sixth USPTO patent

Research shows honey bees change their circadian rhythms

Cancer Research UK launches programme to turn genetic revolution into better treatment for cancer patients

Scientists identify gene that could predict breast cancer patients' response to tamoxifen

Imprime PGG and cetuximab increase overall response rate in metastatic colorectal cancer

Scientists design synthetic molecule to protect liver cancer cells from toxic effects of chemotherapy

Defect in 21st amino acid leads to progressive brain atrophy: Study

HSV1716 clinical trial for childhood cancer receives FDA grant

Scientists identify mutant protein in type 2 diabetes

Engaging in healthy lifestyle can help women with family history control breast cancer risk

Global study finds new set of genes associated with body fat distribution and obesity

Researchers develop new method to identify chemical histone modifications

Healthy lifestyle can reduce breast cancer risk in women with family history

Persistent exposure to light at night leads to weight gain

Biologists recommend virtual institute for RNA research

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