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Experimental imaging technique reveals ‘tell tale’ brain plaques in Alzheimer's

Researchers at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have demonstrated a new, highly detailed x-ray imaging technique that could be developed into a method for early diagnosis of Alzheimer's disease.

15 Jun 2009

Research leads to advanced trials of new cancer treatment

Prof. Hochberg was successful in isolating the H19 gene in humans and determining that it is significantly expressed in over 33 different forms of cancer, including superficial bladder carcinoma and pancreatic, ovarian and metastatic liver cancer, while laying dormant and non-expressed in non-cancerous cells.

15 Jun 2009

New optical colon cancer screening technique shows promise

Recent clinical trials show that a new colon cancer screening technique created by Northwestern University researchers has a high enough sensitivity that it could potentially be as or more successful than a colonoscopy in screening for colon cancer.

10 Jun 2009

Novel approach for treating cognitive impairments

Researchers have been seeking a safe and effective way to treat cognitive impairments associated with schizophrenia by enhancing N-methyl-D-aspartate (NMDA) glutamate receptors. Functional deficits in NMDA receptors may contribute to the underlying neurobiology of this disorder.

9 Jun 2009

Novel diabetes treatment Syncria (albiglutide) improves glucose control and reduces weight

New Phase II data presented today at the American Diabetes Association 69th Scientific Sessions in New Orleans show that the investigational type 2 diabetes treatment Syncria (albiglutide) significantly reduced blood glucose levels and provided weight loss across weekly, biweekly and monthly dosing. Reducing blood sugar is a key part of managing type 2 diabetes, a disease that affects over 250 million people worldwide.

9 Jun 2009

Do omega-3 fatty acids prevent depression in coronary heart disease?

Depression is an established risk factor for the development of coronary heart disease (CHD) in healthy patients and for adverse cardiovascular outcomes in patients with existing CHD. Dietary factors resulting in lower levels of omega-3 fatty acids not only increase CHD risk, but may also be involved in the pathophysiology of depression.

9 Jun 2009

WHO to incorporate disease severity into pandemic alert scale

A meeting of the WHO's emergency committee held Friday to discuss the H1N1 (swine) flu ended without a pandemic declaration, but experts concluded that declarations would now be based upon the severity and transmission pattern of a virus, Reuters reports (Nebehay, Reuters, 6/5). "The Emergency Committee is composed of international experts and its task is to give advice to the WHO chief on influenza outbreak responses," according to Xinhua writes (Xinhua, 6/6).

9 Jun 2009

Prevalence and predictors of antioxidant supplement use during breast cancer treatment

A new study finds that many women with breast cancer take antioxidant supplements while undergoing cancer treatment, even though the consequences of doing so are unknown.

9 Jun 2009

WHO recommends worldwide use of rotavirus vaccine for children

To reduce an estimated half million deaths and two million hospitalizations from diarrhea caused by rotavirus each year, the WHO on Friday recommended that oral rotavirus vaccines be added to national childhood immunization programs, broadening access to the vaccine in the developing world, Reuters reports.

5 Jun 2009

Tuberculosis booster vaccine trials to begin next month In South Africa

A new two-year trial to test a tuberculosis vaccine aimed at boosting the efficacy of the BCG vaccine is scheduled to begin soon in South Africa, IRIN reports (IRIN, 6/4).

5 Jun 2009

WHO recommends global use of rotavirus vaccines - can protect millions of children from diarrhoeal diseaseas

The World Health Organization (WHO) has recommended that rotavirus vaccination be included in all national immunization programmes to provide protection against a virus that is responsible for more than 500,000 diarrhoeal deaths and 2 million hospitalizations every year among children. More than 85% of these deaths occur in developing countries in Africa and Asia. This new policy will help ensure access to rotavirus vaccines in the world's poorest countries.

5 Jun 2009

Cancer vaccine efficacy enhanced using anti-diabetic drug Metformin

After a vaccination or an infection, the human immune system remembers to keep protecting against invaders it has already encountered, with the aid of specialized B-cells and T-cells. Immunological memory has long been the subject of intense study, but the underlying cellular mechanisms regulating the generation and persistence of long-lived memory T cells remain largely undefined. Now, University of Pennsylvania School of Medicine researchers have found that a common anti-diabetic drug might enhance the effectiveness of vaccines. The findings are described this week in an advanced online publication of Nature.

4 Jun 2009

Discovery of critical marker of response to gemcitabine in pancreatic cancer

A protein related to aggressive cancers can actually improve the efficacy of gemcitabine at treating pancreatic cancer, according to a Priority Report in Cancer Research, published by researchers at Thomas Jefferson University.

4 Jun 2009

Prophylactic cranial irradiation prevents early lung cancer metastases to the brain

A national Radiation Therapy Oncology Group (RTOG) study led by a Medical College of Wisconsin Cancer Center physician at Froedtert Hospital in Milwaukee has found that a course of radiation therapy to the brain after treatment for locally advanced non-small cell lung cancer reduced the risk of metastases to the brain within the first year after treatment. The study was presented at the American Society of Clinical Oncology annual meeting in Orlando, June 1.

3 Jun 2009

SmartPill capsule for ulcerative colitis patients

An electronic diagnostic tool called the SmartPill is swallowed by patients in order to take measurements as it travels through the gastrointestinal tract.

3 Jun 2009

Benefit to women not enough to sway men to get HPV vaccine

Informing men that a new vaccine to prevent human papillomavirus (HPV) would also help protect their female partners against developing cervical cancer from the sexually transmitted infection did not increase their interest in getting the vaccine, according to a new Florida State University study.

2 Jun 2009

Study to evaluate ‘Active Hexose Correlated Compound’ and the swine flu virus

A study evaluating the effect of AHCC (Active Hexose Correlated Compound) on supporting the immune system in response to the swine flu virus will be conducted at the Southern China Agricultural University, one of the few research centers in China that have been approved to conduct studies on highly infectious diseases such as the swine flu. This controlled study will examine the effects of AHCC when supplemented to a group of mice infected with the virus.

1 Jun 2009

Vandetanib shows clinical benefit when combined with docetaxel for lung cancer

When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according to research from The University of Texas M. D. Anderson Cancer Center.

1 Jun 2009

Drug combo improves outcome for advanced non-small cell lung cancer

A new, international study found that the combination of two drugs delays disease progression for patients with advanced non-small cell lung cancer (NSCLC).

1 Jun 2009

FDA approves Reclast (zoledronic acid) for osteoporosis in postmenopausal women

Reclast (zoledronic acid) Injection has been approved by the US Food and Drug Administration (FDA) as the first and only therapy to prevent postmenopausal osteoporosis for two years with a single dose. Reclast is already approved as a once-yearly infusion for the treatment of postmenopausal osteoporosis.

1 Jun 2009