Research News and Research

RSS

DNA free radical damage research

Certain prostate cancer cell lines are unable to repair DNA damage caused by "free radicals," according to scientists at the National Institute of Standards and Technology (NIST) and National Institutes of Health (NIH). This type of damage has been implicated before in the development of prostate cancer, but the new research provides the first solid evidence that the normal repair process is altered in prostate cancer cells, possibly leading to a cascade of events that culminate in further DNA damage and cellular dysfunction.

9 Apr 2004

Magnetic tweezers that can manipulate strands of DNA

An array of magnetic traps designed for manipulating individual biomolecules and measuring the ultrasmall forces that affect their behavior has been demonstrated by scientists at the National Institute of Standards and Technology (NIST).

9 Apr 2004

African summit on treatment of AIDS, tuberculosis and malaria

In Gaborone, Botswana, government officials and representatives of drug regulatory agencies from 23 nations, the research-based and generic pharmaceutical industries, public health leaders, health care providers, advocacy groups (including persons living with HIV/AIDS), academia and members of non-governmental organizations held discussions from March 29-31 on the scientific and technical principles for fixed-dose combination drug products (FDCs) for use in the treatment of AIDS, tuberculosis and malaria, the most serious infectious disease threats facing the world today.

8 Apr 2004

Cell research to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease

Medical Research Council (MRC) scientists have made an important advance in understanding the biological processes involved when cells die. The work may help scientists to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease.

8 Apr 2004

Unique heart arrhythmia drug represents one of the first molecular-based therapies for heart failure

Heart researchers at Columbia University Medical Center have developed and tested a unique heart arrhythmia drug that could prevent the sudden death of millions of people with heart failure as well as people with an inherited heart disorder. The drug represents one of the first molecular-based therapies for heart failure and avoids the toxicity of current treatments.

8 Apr 2004

New process to extract proteins from membranes by using chemicals

Proteins are complex compounds that are essential for the growth and repair of tissue. While scientists understand much about the structure and stability of water-soluble proteins that ‘float’ around in humans, they know very little about the shape and stability of proteins that are embedded, or folded, into the lipid membrane of cells. Such membrane proteins make up about 30 percent of all proteins in the body.

8 Apr 2004

New microgel could potentially recover any enzyme and save manufacturers considerable money

Carnegie Mellon University scientists have employed biological molecules to create a microgel that could recover costly enzymes for repeated use in catalyzing commercially important reactions. The microgel could potentially recover any enzyme and theoretically save manufacturers considerable money.

8 Apr 2004

Cervical cancer screening in Northern Ireland falls short

Only 72 per cent of women within the target age group in the Province had a cervical smear test in the five-year period up to 31 March 2003 – contrasting with higher figures for England, Scotland and Wales. NHS targets for cervical screening call for a minimum of 80 per cent of Northern Ireland women aged between 20 and 65 to be screened every five years.

8 Apr 2004

Breast-feeding may protect against SIDS

Breast-fed babies arouse more readily from deep sleep, Monash researchers have found, in a discovery that could help reduce deaths due to Sudden Infant Death Syndrome (SIDS).

7 Apr 2004

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

The technique, described in the current issue of Molecular Therapy, could eventually lead to a method to correct genetic conditions in humans that cause diaphragm weakness and respiratory failure -- a leading cause of death in tens of thousands of patients with forms of muscular dystrophy, including Pompe’s disease. Thousands of Americans with muscle-weakening diseases are placed on ventilators each year, according to the Muscular Dystrophy Association.

7 Apr 2004

Shunning shoulder pain can cause more damage in the long run

Senator John Kerry is one of the millions of Americans suffering from shoulder pain. Depending on the nature of the problem, conservative nonoperative methods of treatment are often recommended before surgery. However, in some instances such as Kerry’s, surgery is necessary in order to prevent more difficulties later. The American Academy of Orthopaedic Surgeons (AAOS) advises those suffering shoulder pain to consult their doctor instead of ignoring the pain. Early, correct diagnosis and treatment of shoulder problems can make a significant difference in the long run.

7 Apr 2004

Results of Creutzfeldt-Jakob disease research in people who received human growth hormone from cadavers

The largest study of its kind, designed to track the development of Creutzfeldt-Jakob disease in people who received human growth hormone from cadavers, has found that the vast majority of those who received the hormone did not contract the fatal condition. However, some recipients (26 out of approximately 7,700) did develop the disease.

7 Apr 2004

The Cambridge-MIT Institute has launched a project to tackle the bottlenecks that slow development of new drugs

The Next-Generation Drug Discovery Community will unite researchers at Cambridge University and MIT with partners from the information technology, pharmaceutical and biotechnology industries to find ways to speed up development of the next generation of drugs--particularly those that treat diseases with complex causes such as cancers, arthritis, multiple sclerosis and diabetes.

7 Apr 2004

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Continuing studies about an important regulatory protein kinase complex called I-kappa-B kinase (or IKK) have now shown that a subunit of IKK – IKK alpha – influences the outer layer of skin in developing mice to control the eventual shape of the full-grown skeleton and skull.

7 Apr 2004

Genetic trick makes gene therapy vectors more versatile

A genetic trick used by viruses to replicate themselves has been adapted for laboratory use to build complex protein structures required by immune system cells, according to investigators at St. Jude Children’s Research Hospital.

7 Apr 2004

Molecular analyses of leukemia patients suggest strategies for better treatments

The cure rate for pediatric acute lymphoblastic leukemia (ALL) might continue to rise with improved use of conventional therapies. But even more effective and less toxic therapies based on genetic and pharmacogenetic studies might one day push the success rate close to 100 percent, according to an article published by investigators at St. Jude Children’s Research Hospital in the April 8 issue of the New England Journal of Medicine.

7 Apr 2004

Pharmacopeia announces that proposed spin-off of Pharmacopeia Drug Discovery, Inc. unit is expected to occur by the end of April 2004

Pharmacopeia, Inc. today announced that the proposed spin-off of its Pharmacopeia Drug Discovery, Inc. (PDD) unit is expected to occur by the end of April 2004. The Pharmacopeia Board of Directors intends to meet next week to consider final approval of the pro rata distribution to stockholders of 100% of the common stock of PDD.

7 Apr 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

If you want to increase your chances of living longer, taking cholesterol drugs is an easy way to do it. That's the message from a Harvard study of 4,162 people hospitalized in 350 places in eight countries. It is the first research to show that intense lowering of cholesterol results in a major reduction in deaths and severe heart attacks.

7 Apr 2004

A protein involved in the release of neurotransmitters in the brain is essential to learning and memory

A study published today in Neuron offers the first evidence that lack of this protein - known as RIM1 alpha - causes profound deficits in the learning process. The discovery is a major step in understanding the molecular events that underlie learning and memory - complex processes that can be impaired in human neuropsychiatric disorders such as Alzheimer's disease, mental retardation and schizophrenia.

7 Apr 2004

Time-reversal acoustics research promises medical breakthroughs

Scientists have not yet found a way to actually make time run backward, but in the cutting-edge world of recent acoustics research, they have shown a way to make sound waves run backward in a kind of ultra-focused reverse echo. By the technology known as time-reversal acoustics, sound waves - in exact reverse order from the original sound - echo directly and very precisely back to their source point.

7 Apr 2004

Research News and Research

DNA free radical damage research

Magnetic tweezers that can manipulate strands of DNA

African summit on treatment of AIDS, tuberculosis and malaria

Cell research to eventually develop new treatments for cancer and disorders such as Parkinson’s and Huntington’s disease

Unique heart arrhythmia drug represents one of the first molecular-based therapies for heart failure

New process to extract proteins from membranes by using chemicals

New microgel could potentially recover any enzyme and save manufacturers considerable money

Cervical cancer screening in Northern Ireland falls short

Breast-feeding may protect against SIDS

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

Shunning shoulder pain can cause more damage in the long run

Results of Creutzfeldt-Jakob disease research in people who received human growth hormone from cadavers

The Cambridge-MIT Institute has launched a project to tackle the bottlenecks that slow development of new drugs

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Genetic trick makes gene therapy vectors more versatile

Molecular analyses of leukemia patients suggest strategies for better treatments

Pharmacopeia announces that proposed spin-off of Pharmacopeia Drug Discovery, Inc. unit is expected to occur by the end of April 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

A protein involved in the release of neurotransmitters in the brain is essential to learning and memory

Time-reversal acoustics research promises medical breakthroughs

A guide to advancing biotherapeutic research eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Latest Life Science News