Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

In this analysis we brought together the few European studies that have looked, within geographical areas, at the prevalence or incidence of dementia in the population aged 65 and over.

7 Dec 2015

The Importance of Flexibility in Spectrophotometry

News-Medical speaks to Jessica Geisler about the need for flexible spectrophotometers that can handle a range of measurement types.

From Eppendorf 1 Dec 2015

Novel class of antimicrobials could be effective in fighting drug-resistant MRSA infection

A novel class of antimicrobials that inhibits the function of a key disease-causing component of bacteria could be effective in fighting methicillin-resistant Staphylococcus aureus (MRSA), one of the major drug-resistant bacterial pathogens, according to researchers at Georgia State University.

1 Dec 2015

Heptares announces strategic drug discovery collaboration with Pfizer

Heptares Therapeutics, the clinical-stage GPCR structure-guided drug discovery and development company and wholly-owned subsidiary of Sosei Group Corporation, announces that it has entered into a strategic drug discovery collaboration with Pfizer Inc. to research and develop potential new medicines directed at up to 10 G protein-coupled receptor (GPCR) targets across multiple therapeutic areas.

30 Nov 2015

Interaction between two brain proteins has substantial effect on memory formation

In a new study that could have implications for future drug discovery efforts for a number of neurodegenerative diseases, scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that the interaction between a pair of brain proteins has a substantial and previously unrecognized effect on memory formation.

20 Nov 2015

Med Data Quest collaborates with WuXi AppTec to tackle oncology informatics challenges

Med Data Quest, a pioneering medical informatics total solution provider, today celebrates its successful collaboration with the Oncology Business Unit of the CRO giant WuXi AppTec, delivering the world's first mobile App OncoWuXi that was launched in October for customers to access WuXi oncology tumor models and capabilities more quickly and easily for cancer drug discovery and translational research.

18 Nov 2015

Corning signs agreement to become global distributor for popular BioCision products

Corning Incorporated and BioCision, LLC today announced an agreement that will enable laboratories around the world to further standardize and simplify key steps in their cell culture workflow.

17 Nov 2015

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Salk Institute researchers have found that an experimental drug candidate aimed at combating Alzheimer's disease has a host of unexpected anti-aging effects in animals.

13 Nov 2015

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

A University of South Florida Center for Global Health & Infectious Diseases Research team has demonstrated a new screening model to classify antimalarial drugs and to identify drug targets for the most lethal strain of malaria, Plasmodium falciparum.

12 Nov 2015

Mike and Alice Jackson announce $1 million pledge to support NSU's cancer research

For Mike and Alice Jackson, cancer is personal; so much so that they are joining with Nova Southeastern University researchers in the fight against one of the nation's deadliest diseases. The Jacksons announced today a $1 million personal pledge to support NSU's cancer research.

12 Nov 2015

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease.

11 Nov 2015

Florida Institute finalizes funding agreement with Genetic Networks

The Florida Institute for the Commercialization of Public Research (the Institute) announced today that it has finalized a funding agreement with Genetic Networks, a Miami based company with technology developed at the University of Miami.

11 Nov 2015

Understanding how schizophrenia affects workings of the brain

Stem cells from adult schizophrenia patients form new proteins more slowly than those from healthy people, according to new research.

10 Nov 2015

St. Jude and Scripps Research Institute scientists help launch Human Dark Proteome Initiative

Scientists at St. Jude Children’s Research Hospital, The Scripps Research Institute (TSRI) and other institutions today announced the launch of the Human Dark Proteome Initiative (HDPI). The initiative aims to accelerate research into biology’s “invisible mass” to provide novel insights into cell function and a new frontier in drug discovery.

9 Nov 2015

Scientists discover small molecule that can block growth of BRCA-deficient cancer cells

Cancer cells with mutations in BRCA1 or BRCA2 genes, which serve a vital role in preserving the integrity of the genetic code, are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient in BRCA, and none can do so without the risk of inducing drug resistance.

6 Nov 2015

Denator forms a new Scientific Advisory Board

Denator AB has announced that a new external expert advisory board has been formed. Karsten Fjärstedt, recently appointed as CEO comments, “It is a great honor for me to be entrusted to lead Denator forward in this new phase of development. With a pipeline of new exciting business opportunities and a strong Scientific Advisory Board (SAB) I am looking forward to realizing the full potential of the company technology”.

3 Nov 2015

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Alnylam Pharmaceuticals, Inc. has announced new results from its ongoing Phase 2 open-label extension (OLE) studies with patisiran and revusiran, investigational RNAi therapeutics targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR amyloidosis).

3 Nov 2015

Researchers develop biochemical trick that can extend lifespan of peptides

Researchers at University of the Pacific have developed a biochemical trick that can significantly extend the lifespan of peptides, smaller cousins of proteins. The finding opens up new possibilities for creating peptides to treat cancer, infertility and other conditions.

3 Nov 2015

Griffith University uncovers first 3-D image of protein linked to cancer spread

Griffith University's Institute for Glycomics has made scientific history by determining the first three-dimensional image of a protein linked to the spread of cancer.

3 Nov 2015

Love hormone may enhance pleasure of social interactions, UCI study finds

The hormone oxytocin, which has been associated with interpersonal bonding, may enhance the pleasure of social interactions by stimulating production of marijuana-like neurotransmitters in the brain, according to a University of California, Irvine study.

27 Oct 2015

Drug Discovery News and Research

Further Reading

Risk of dementia decreasing? An interview with Professor Carol Brayne, University of Cambridge

The Importance of Flexibility in Spectrophotometry

Novel class of antimicrobials could be effective in fighting drug-resistant MRSA infection

Heptares announces strategic drug discovery collaboration with Pfizer

Interaction between two brain proteins has substantial effect on memory formation

Med Data Quest collaborates with WuXi AppTec to tackle oncology informatics challenges

Corning signs agreement to become global distributor for popular BioCision products

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Researchers demonstrate new screening model to identify drug targets for the most lethal strain of malaria

Mike and Alice Jackson announce $1 million pledge to support NSU's cancer research

New progenitor cells differentiate into mature cell types, prevent risk of unwanted tumors

Florida Institute finalizes funding agreement with Genetic Networks

Understanding how schizophrenia affects workings of the brain

St. Jude and Scripps Research Institute scientists help launch Human Dark Proteome Initiative

Scientists discover small molecule that can block growth of BRCA-deficient cancer cells

Denator forms a new Scientific Advisory Board

Alnylam presents positive ongoing phase 2 open-label extension data for Patisiran and Revusiran

Researchers develop biochemical trick that can extend lifespan of peptides

Griffith University uncovers first 3-D image of protein linked to cancer spread

Love hormone may enhance pleasure of social interactions, UCI study finds

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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