Tumor News and Research

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Broken bones may reduce risk of ovarian cancer

The pain and suffering of a broken bone may yield an unexpected benefit – a reduced risk of ovarian cancer.

10 May 2005

Breast CT may improve on mammography - more gentler, more accurate

A new breast screening technology that may be able to detect tumors earlier than mammography -- without the need for uncomfortable breast compression -- is being tested in patients at the University of California, Davis, Medical Center.

10 May 2005

New laser technology for more precise cancer treatments

Tom Cowan’s team is thinking smaller, but with big impact. Particle accelerators are a key research tool in a high energy physicist’s arsenal, but they take up a lot of space - miles and miles of it. But at the University of Nevada, Reno, smaller is better.

10 May 2005

Research offers new molecular approaches to therapies for the most deadly cancers

Researchers at Wake Forest University Baptist Medical Center have found promising new molecular targets and treatment approaches for some of the most malignant brain tumors.

10 May 2005

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists at St. Jude Children’s Research Hospital have joined with colleagues at several other institutions to develop a laboratory model of the human immune system. This model will allow scientists to study ways for improving the results of hematopoietic stem cell (HSC) transplantation without putting patients at risk.

10 May 2005

Scientists inhibit tumor formation

By studying mice with skin cancer, researchers at the Huntsman Cancer Institute at the University of Utah discovered a way to inhibit a mutant gene found in up to 30 percent of human tumors.

9 May 2005

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

After surgery check colon tumors for signs of syndrome, study suggests

A new study suggests that, after surgery, all colon tumors should be tested to learn if the patient may have an inherited syndrome that carries an extremely high risk of cancer. It also suggests that this prescreening can be done using a relatively inexpensive microscopy test already used in hospital pathology laboratories.

5 May 2005

Cancer hijacks normal wound-healing processes

Scientists have known for the last decade that a link exists between wound healing and cancer. For instance, in a 1994 experiment at the Lawrence Berkeley National Laboratory, chickens infected with a cancer virus developed tumors in areas of their body that had undergone wounding or scarring, while no tumors developed in infected areas that had not suffered wounding.

5 May 2005

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Researchers at the University of Pennsylvania School of Medicine have identified in normal cells that a common metabolic enzyme, which acts as a rheostat of cellular conditions, also controls cell replication.

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

pSivida's BrachySil takes first step in regulatory programme leading to product approval

pSivida Limited has announced that current data from its lead cancer product BrachySil will be presented at this year's European Society for Therapeutic and Radiation Oncology Conference in Budapest on May 5, 2005. The conference is an opportunity to share and validate the Company's promising findings with an international scientific, clinical and industrial audience.

3 May 2005

Study identifies possible marker for efficacy of gefitinib in lung cancer patients

Patients with advanced non–small-cell lung cancer (NSCLC) whose tumor cells contain extra copies of the epidermal growth factor receptor (EGFR) gene may be more likely to respond to the drug gefitinib (Iressa), and this high gene copy number may be an effective predictor of gefitinib efficacy, according to a new study in the May 4 issue of the Journal of the National Cancer Institute.

3 May 2005

Scientists use tobacco plants to create antibodies against tumor cells

Scientists at Jefferson Medical College are using tobacco plants to produce monoclonal antibodies – tiny guided protein missiles – that can target and hunt down cancer cells. The plants promise to provide a cheaper, faster method of producing anticancer antibodies, raising hopes that the technology can one day be used in humans.

3 May 2005

Long-term outcomes promising for patients with localized, low-grade prostate cancer

A study that includes 20 years of follow-up does not support aggressive treatment for localized, low-grade prostate cancer, with data indicating a small risk of progression of this grade of cancer, according to a study in the May 4 issue of JAMA.

3 May 2005

Critical lock and key mechanism found for the assembly of tumor blood vessels

A critical lock and key mechanism that allows the final step in the completion of new blood vessel formation has been identified by a University of California, San Diego (UCSD) School of Medicine team in research that promises to lead to a new way to halt tumor growth by cutting off the tumor blood supply.

3 May 2005

Tumors of the pituitary gland are more common than thought

A recent study found that tumors of the pituitary gland are more common than many health care professionals realize, with national prevalence rates averaging 16.7 percent. To neurosurgeon Dr. Gail Rosseau, this isn't surprising.

1 May 2005

Blocking the COX-1 enzyme might prevent and treat the most common and fatal form of ovarian cancer

Blocking the COX-1 enzyme - not COX-2 - might lead to a way to prevent and treat the most common and fatal form of ovarian cancer, researchers at Vanderbilt University Medical Center reported this week.

1 May 2005

Researchers determine mechanism of action of chemotherapy drug motexafin gadolinium

The chemotherapy drug motexafin gadolinium (brand name: Xcytrin, manufactured by Pharmacyclics, Inc.) works to thwart cancer cells by disrupting key enzymes involved in cellular metabolism, according to a team of researchers led by Joseph Hacia, Ph.D., assistant professor of biochemistry and molecular biology at the Keck School of Medicine of the University of Southern California.

1 May 2005

Tumor News and Research

Broken bones may reduce risk of ovarian cancer

Breast CT may improve on mammography - more gentler, more accurate

New laser technology for more precise cancer treatments

Research offers new molecular approaches to therapies for the most deadly cancers

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists inhibit tumor formation

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

After surgery check colon tumors for signs of syndrome, study suggests

Cancer hijacks normal wound-healing processes

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

pSivida's BrachySil takes first step in regulatory programme leading to product approval

Study identifies possible marker for efficacy of gefitinib in lung cancer patients

Scientists use tobacco plants to create antibodies against tumor cells

Long-term outcomes promising for patients with localized, low-grade prostate cancer

Critical lock and key mechanism found for the assembly of tumor blood vessels

Tumors of the pituitary gland are more common than thought

Blocking the COX-1 enzyme might prevent and treat the most common and fatal form of ovarian cancer

Researchers determine mechanism of action of chemotherapy drug motexafin gadolinium

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Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

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