Tumor News and Research

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Chemical thumbprint can help determine if tumor is returning or dying

Brain tumor survivors live with the constant worry that their cancer might come back. And even if they have a brain scan every few months to check, doctors often can't tell the difference between new cancer growth and tissue changes related to their treatment with radiation or chemotherapy.

3 May 2004

New technique to deliver gene therapy to soft-tissue tumors

Using new research and technology that shows bone marrow-derived mesenchymal stem cells (MSCs) will engraft at the site of a tumor and contribute to the growth of stromal fibroblasts (the healthy tissue surrounding a tumor)

2 May 2004

Protein expression of the tumor suppressing gene could play a vital role in ovarian cancer

Protein expression of the tumor suppressing gene Rb2/p130 could play a vital role in ovarian cancer, according to a study by researchers at the Sbarro Institute for Cancer Research and Molecular Medicine in the Center for Biotechnology at Temple University

1 May 2004

Researchers profile over 6000 genes in the two primary types of normal breast cells

For several years, scientists have attempted to identify gene expression changes, using microarrays or ‘DNA chips’, in order to understand and predict breast cancer onset, progression, and clinical outcome.

1 May 2004

Developing smart drugs

Dana-Farber Cancer Institute Researchers, sensing an opening in the cancer battle, are mounting a quick thrust to flush out suspected molecular cancer triggers in tumor cells.

30 Apr 2004

Combination of real-time PET and CT is a highly sensitive tool for identifying non-small cell lung cancer

The combination of real-time PET and CT is a highly sensitive tool for identifying non-small cell lung cancer (NSCLC) and can assist in identifying patients whose cancer has not yet spread to lymph nodes, according to results of a study by researchers at Johns Hopkins.

30 Apr 2004

Researchers find mucus plays key role in cancer

Investigators at the Dana-Farber/Harvard Cancer Center in Boston became intrigued with the thick, slimy stuff when they learned that breast, lung, colon, and other tumor cells make more than 50 times more of a certain type of it than normal cells.

29 Apr 2004

A new prognostic marker has shown potential to predict recurrence in certain colon cancer patients

In the study, a team of researchers led by Veridex, LLC, a Johnson & Johnson company, used gene expression profiling to identify the new marker – a 23-gene signature – which may predict disease recurrence in patients initially diagnosed with Dukes' B colon cancer.

29 Apr 2004

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Mutation of a gene involved in non-small cell lung cancer (NSCLC) increases the likelihood that the drug gefitinib (Iressa™) will show a beneficial response, researchers at the Dana-Farber Cancer Institute, the National Cancer Institute (NCI) - part of the National Institutes of Health - and two other institutions announced today in the online version of Science.

29 Apr 2004

Pediatric thyroid cancer is most common amongs teenage girls

Thyroid carcinoma is the third most common tumor malignancy in children. This pediatric cancer shares several characteristics with adult thyroid cancer patients including common cellular subtypes that are papillary, follicular and medullary; a female to male ratio is approximately 6:1; and a cervical nodal disease that can be observed at the time of presentation in 30-60 percent in both papillary and follicular malignancies.

29 Apr 2004

Study shows prostate brachytherapy using ‘Radioactive Seeds’ is an effective alterantive to surgery or external radiation

Radiation oncologists and urologists at The Cleveland Clinic have performed their 1,000th prostate brachytherapy, a type of treatment in which radioactive seeds are implanted in the prostate to destroy cancerous cells.

28 Apr 2004

PET imaging has recently been shown to aid in the diagnosis of particular neurological syndromes associated with cancer

PET imaging has been shown to improve detection of a variety of cancers, and earlier tests have suggested this technique may be useful in identifying small tumors in patients with paraneoplastic neurological disorders. But PET imaging is not yet widely available, and clear indicators of clinically meaningful outcomes using PET are essential to warrant use with this patient population.

28 Apr 2004

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

In a paper that will be published on Thursday, April 29, 2004 in the New England Journal of Medicine, a team of scientists from Stanford University and Applied Biosystems, an Applera Corporation business, describe the identification of six genes associated with survival in diffuse large B cell lymphoma (DLBCL), the most common form of non-Hodgkin's lymphoma.

28 Apr 2004

Carbohydrate-binding proteins are becoming extremely useful in curing various illnesses

Researchers are beginning to see the potential for breakthrough in healthcare through glycomics, which studies carbohydrates, proteins and their interactions. In fact, these carbohydrates are moving beyond their regular roles as sugar storage bins.

28 Apr 2004

AGT Biosciences Limited and ChemGenex Therapeutics today announced merger agreement

AGT Biosciences Limited of Melbourne, Australia and privately held ChemGenex Therapeutics, Inc. of Menlo Park, California, today announced that they have signed a merger agreement. The cross-border merger creates a new, genomics-driven pharmaceutical company with leading edge capabilities for drug discovery and development, as well as two drug candidates in Phase II human trials for cancer.

28 Apr 2004

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

Researchers at Duke University have developed a new analytical approach that combines genetic and clinical data to give cancer patients an individualized prognosis of their cancer recurrence. The information could prove critical in deciding how aggressively to treat the disease following surgery.

26 Apr 2004

The April 2004 issue of Otolaryngology focuses on head and neck surgery

The efficacy of a new cancer-fighting virus is tested in the study, “Treatment of Solid Sarcomas in Immunocompetent Mice with Novel Oncolytic Herpes Simplex Viruses.” A team of multi-disciplinary Japanese researchers found that a weakened version of herpes simplex virus (HSV) effectively eradicated neck and flank tumors in mice.

23 Apr 2004

Potential new drug may slow the progression of the Parkinson's disease

An international team of Parkinson's disease researchers has shown that a potential new drug is effective at treating patients in the early stages of Parkinson's and may even slow the progression of the disease. The results from the Parkinson Study Group are in the April 19 issue of the Archives of Neurology.

22 Apr 2004

500,000 patients have now been treated with REMICADE® worldwide

Centocor, Inc., announced today that more than a half million patients worldwide have now been treated with the anti-TNF agent REMICADE® (infliximab) since it was introduced in the United States five years ago.

21 Apr 2004

New drug is effective at treating patients in the early stages of Parkinson’s

An international team of Parkinson’s disease researchers has shown that a potential new drug is effective at treating patients in the early stages of Parkinson’s and may even slow the progression of the disease.

20 Apr 2004

Tumor News and Research

Chemical thumbprint can help determine if tumor is returning or dying

New technique to deliver gene therapy to soft-tissue tumors

Protein expression of the tumor suppressing gene could play a vital role in ovarian cancer

Researchers profile over 6000 genes in the two primary types of normal breast cells

Developing smart drugs

Combination of real-time PET and CT is a highly sensitive tool for identifying non-small cell lung cancer

Researchers find mucus plays key role in cancer

A new prognostic marker has shown potential to predict recurrence in certain colon cancer patients

Mutation of a gene involved in non-small cell lung cancer linked to drug effectiveness

Pediatric thyroid cancer is most common amongs teenage girls

Study shows prostate brachytherapy using ‘Radioactive Seeds’ is an effective alterantive to surgery or external radiation

PET imaging has recently been shown to aid in the diagnosis of particular neurological syndromes associated with cancer

Scientists identify six genes associated with the most common form of non-Hodgkin's lymphoma

Carbohydrate-binding proteins are becoming extremely useful in curing various illnesses

AGT Biosciences Limited and ChemGenex Therapeutics today announced merger agreement

New analytical approach that combines genetic and clinical data to give individualized prognosis of cancer recurrence

The April 2004 issue of Otolaryngology focuses on head and neck surgery

Potential new drug may slow the progression of the Parkinson's disease

500,000 patients have now been treated with REMICADE® worldwide

New drug is effective at treating patients in the early stages of Parkinson’s

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