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Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD

Alexion Pharmaceuticals, Inc. today announced positive topline results from the Phase 3 PREVENT study of Soliris in patients with anti-aquaporin-4 auto antibody-positive neuromyelitis optica spectrum disorder.

24 Sep 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI

Biogen and Eisai Co., Ltd. announced results from a recent analysis of the ongoing long-term extension Phase 1b study of aducanumab, an investigational treatment for mild cognitive impairment due to Alzheimer's disease and mild AD dementia.

24 Sep 2018

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

Ipsen announced today that the Committee for Medicinal Products for Human Use, the scientific committee of the European Medicines Agency, provided a positive opinion for Cabometyx (cabozantinib) as a monotherapy for the treatment of hepatocellular carcinoma in adults who have been previously treated with sorafenib.

21 Sep 2018

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

A clinical trial testing infusions of combination antibodies in people living with HIV has begun at the National Institutes of Health.

20 Sep 2018

AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

AmpliPhi Biosciences Corporation, a clinical-stage biotechnology company focused on precisely targeted bacteriophage therapeutics for antibiotic-resistant infections, today announced that the company has received positive feedback, via written response, from the U.S. Food and Drug Administration regarding its development plans for AB-PA01, without the need for a Type B Pre-IND meeting.

19 Sep 2018

Novel clinical trial to examine cannabis as potential treatment for essential tremor

Researchers at University of California School of Medicine are preparing to launch a novel clinical trial to examine the safety, efficacy and pharmacological properties of cannabis as a potential treatment for adults with essential tremor.

18 Sep 2018

Resveratrol decreases pain severity and levels of inflammatory biomarkers in osteoarthritis patients

In what researchers state is the first pilot clinical trial to assess the effects of resveratrol on pain severity and levels of inflammatory biomarkers in patients with mild to moderate knee osteoarthritis, the scientists compared treatment with a nonsteroidal anti-inflammatory drug combined with either resveratrol or placebo over 90 days.

18 Sep 2018

ASPREE trial explores whether low dose aspirin can prolong good health in elderly people

The ASPREE trial of more than 19,000 participants in Australia and the US is the largest and most comprehensive study to look at whether the many millions of older people around the world who take (100mg) low dose aspirin to preserve good health are deriving any benefit by doing so.

18 Sep 2018

Investigational nasal influenza vaccine tested in children and teens

An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit site at Saint Louis University, St. Louis, Missouri.

17 Sep 2018

Probiotic supplementation may reduce use of antibiotics, scientific analysis shows

Global demand exists for new ways to reduce antibiotic use, given the urgent public health threat of antibiotic resistance.

17 Sep 2018

Study reveals long-term safety, efficacy of Ofev in patients with idiopathic pulmonary fibrosis

Results from INPULSIS-ON, published today in Lancet Respiratory Medicine, provide insights into the long-term safety, efficacy, and tolerability of Ofev (nintedanib) in patients with idiopathic pulmonary fibrosis (IPF).

17 Sep 2018

FDA approves Teva’s AJOVY injection for preventive treatment of migraine in adults

Teva Pharmaceutical Industries Ltd. today announced that the U.S. Food and Drug Administration has approved AJOVY injection for the preventive treatment of migraine in adults.

17 Sep 2018

Daily low-dose aspirin does not prolong healthy life in older people, study finds

In a large clinical trial to determine the risks and benefits of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living (life free of dementia or persistent physical disability).

17 Sep 2018

FDA-approved 'safe' daily BPA exposure may contribute to insulin resistance

In a first study of its kind study, researchers have found that a common chemical consumers are exposed to several times a day may be altering insulin release.

17 Sep 2018

The use of aspirin in elderly now questioned

A large study led by Australian researchers has found that taking Aspirin tablets regularly to does not really prolong life or reduce the risk of a first heart attack or stroke.

16 Sep 2018

Sugar pills may help treat certain chronic pain patients

Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce their pain as effectively as any powerful drug on the market, according to new research.

12 Sep 2018

New evidence does not support use of invasive procedures for patients with chronic pain

An extensive review of 25 randomized clinical trials found "little evidence" that invasive surgery was more effective than sham or placebo procedures in reducing chronic pain. The study was published in the journal Pain Medicine.

12 Sep 2018

New malaria drug starts clinical trials

After decades a new drug against malaria has been developed and first clinical trials of this new investigational drug is soon to begin. Enrolment for the same has already started. This study is to be sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institutes of Health (NIH). It is to take place at the Duke University School of Medicine in Durham, North Carolina.

11 Sep 2018

EC approves update of INVOKANA and VOKANAMET labeling to include changes to indication statement

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the European Commission has granted approval to update the INVOKANA® and VOKANAMET® labeling to include changes to the indication statement for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise.

7 Sep 2018

Placebo News and Research

Alexion announces positive results from Phase 3 PREVENT study of Soliris in patients with NMOSD

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

Biogen and Eisai announce results of LTE Phase 1b study of aducanumab for treating MCI

CHMP provides positive opinion to Cabometyx for previously-treated patients with hepatocellular carcinoma

NIH launches clinical trial to test infusions of combination antibodies in people with HIV

AmpliPhi receives positive feedback from FDA for its AB-PA01 product targeting P.aeruginosa infections

Novel clinical trial to examine cannabis as potential treatment for essential tremor

Resveratrol decreases pain severity and levels of inflammatory biomarkers in osteoarthritis patients

ASPREE trial explores whether low dose aspirin can prolong good health in elderly people

Investigational nasal influenza vaccine tested in children and teens

Probiotic supplementation may reduce use of antibiotics, scientific analysis shows

Study reveals long-term safety, efficacy of Ofev in patients with idiopathic pulmonary fibrosis

FDA approves Teva’s AJOVY injection for preventive treatment of migraine in adults

Daily low-dose aspirin does not prolong healthy life in older people, study finds

FDA-approved 'safe' daily BPA exposure may contribute to insulin resistance

The use of aspirin in elderly now questioned

Sugar pills may help treat certain chronic pain patients

New evidence does not support use of invasive procedures for patients with chronic pain

New malaria drug starts clinical trials

EC approves update of INVOKANA and VOKANAMET labeling to include changes to indication statement

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